DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt49C1 and UGT76B1

DIOPT Version :9

Sequence 1:	NP_001036565.1	Gene:	Ugt49C1 / 37421	FlyBaseID:	FBgn0034605	Length:	530	Species:	Drosophila melanogaster
Sequence 2:	NP_187742.1	Gene:	UGT76B1 / 820307	AraportID:	AT3G11340	Length:	447	Species:	Arabidopsis thaliana

Alignment Length:	529	Identity:	120/529 - (22%)
Similarity:	184/529 - (34%)	Gaps:	167/529 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 LELAEGSKILAVYAFPGKSHFMMHTALIRELVESGHQVTMV-TAFSLEKEQLGSNYT-----EIL 77
            :|..|...::.::.||.:.|......|.......|..:|:: |.|:........::|     :.|
plant     1 METRETKPVIFLFPFPLQGHLNPMFQLANIFFNRGFSITVIHTEFNSPNSSNFPHFTFVSIPDSL 65

  Fly    78 IEP-----VYDFWHDVKLN----FGAQHLFELTRMTNYDFLKMLEIIGLKTTEHALRQPKVRSLI 133
            .||     |.:..||:...    ||             |.||.|          ...:|....:|
plant    66 SEPESYPDVIEILHDLNSKCVAPFG-------------DCLKKL----------ISEEPTAACVI 107

  Fly   134 HAEQKEGVFDLL------LAEQFYQEAFLALAHLYKIPVVTTSTLGYENHMSQMMGLITPWSFVP 192
                    .|.|      |.|:|            ..|.:...|:...
plant   108 --------VDALWYFTHDLTEKF------------NFPRIVLRTVNLS----------------- 135

  Fly   193 HGFMPFTDRMSFLERVKNSYASFYEDMDRLLNYFPKMDAVAREFFGPVL---------TEVPKVK 248
             .|:.|:   .|....:..|.|..|         .|.|:...|.  |.|         ||.|: .
plant   136 -AFVAFS---KFHVLREKGYLSLQE---------TKADSPVPEL--PYLRMKDLPWFQTEDPR-S 184

  Fly   249 HMERQISVM---------LLNSHAPLTT-----ARPTVDAMVP---VGGMHIY----PPKPLPAD 292
            ..:.||.||         :.|:...|.|     ||  ::..||   :|..|.|    ....|..|
plant   185 GDKLQIGVMKSLKSSSGIIFNAIEDLETDQLDEAR--IEFPVPLFCIGPFHRYVSASSSSLLAHD 247

  Fly   293 MQAL--LD-GATEGAIFFSLGSNVQSKDMPVEMLRLFLQVFGSLK---QRVLWKFE------DES 345
            |..|  || .||...|:.|||| :.|.|...     ||::...|:   |..||...      .|.
plant   248 MTCLSWLDKQATNSVIYASLGS-IASIDESE-----FLEIAWGLRNSNQPFLWVVRPGLIHGKEW 306

  Fly   346 ISQLP----DNVMVR----KWLPQADILAHRHVKVFITHGGLFGTQEGVHYAVPMLGIPFYCDQH 402
            |..||    :|:..|    ||.||.::||||....|:||.|...|.||:..|:||:..|.:.||.
plant   307 IEILPKGFIENLEGRGKIVKWAPQPEVLAHRATGGFLTHCGWNSTLEGICEAIPMICRPSFGDQR 371

  Fly   403 LNMNKAVLGGYAISLHFQSITEEILRHSLDQLIHNVTYKENVQRVSDIFRDRPLEPRKSAVYWIE 467
            :|. :.:...:.|.||.::..|.::..:..:.:...:..|.::        :.:.|.|..|   |
plant   372 VNA-RYINDVWKIGLHLENKVERLVIENAVRTLMTSSEGEEIR--------KRIMPMKETV---E 424

  Fly   468 YVIRHRGAS 476
            ..::..|:|
plant   425 QCLKLGGSS 433

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt49C1	NP_001036565.1	egt	22..504	CDD:223071	119/526 (23%)
Ugt49C1	NP_001036565.1	UDPGT	37..498	CDD:278624	116/511 (23%)
UGT76B1	NP_187742.1	Glycosyltransferase_GTB-type	1..444	CDD:415824	120/529 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	76	1.000	Domainoid score	I3136
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	89	1.000	Inparanoid score	I2281
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.050