Protein Alignment Ugt49C1 and UGT8

DIOPT Version :9

• Sequence 1: NP_001036565.1
• Gene: Ugt49C1 / 37421
• FlyBaseID: FBgn0034605
• Length: 530
• Species: Drosophila melanogaster
• Sequence 2: NP_001121646.2
• Gene: UGT8 / 7368
• HGNCID: 12555
• Length: 541
• Species: Homo sapiens
• Alignment Length: 509
• Identity: 151/509 - (29%)
• Similarity: 255/509 - (50%)
• Gaps: 51/509 - (10%)

  Fly    15 LYSQLELAEGSKILAVYAFPGKSHFMMHTALIRELVESGHQVTMVTA----------FSLEKEQL 69
            |:|.:.:|:.:||:.|.....:||..:...|...|.|.||....:.:          :||::
Human    11 LWSAVGIAKAAKIIIVPPIMFESHMYIFKTLASALHERGHHTVFLLSEGRDIAPSNHYSLQR--- 72

  Fly    70 GSNYTEILIEPVYDFWHDVKLNFGAQHLF--ELTRMTNYDFL-KMLEIIGLKTTEHALRQPKVRS 131
               |..|......|.:...|:    :::|  .||.:..:|.| ...:...|....|||    ::.
Human    73 ---YPGIFNSTTSDAFLQSKM----RNIFSGRLTAIELFDILDHYTKNCDLMVGNHAL----IQG 126

  Fly   132 LIHAEQKEGVFDLLLAEQFYQEAFLALAHLYKIPVVTTST-LGYENHMSQMMGLITPWSFVPHGF 195
            |     |:..|||||.:......|: :|||..:.....|| |.|...    :|...|.::||...
Human   127 L-----KKEKFDLLLVDPNDMCGFV-IAHLLGVKYAVFSTGLWYPAE----VGAPAPLAYVPEFN 181

  Fly   196 MPFTDRMSFLERVKNSYASFYEDMDRLLNYFPKMDAVAREFFGPVLTEVPKVKHMERQI---SVM 257
            ...||||:.|:|:||:.......:.......||.:.:.:::  .:|.|    |.|...:   |:.
Human   182 SLLTDRMNLLQRMKNTGVYLISRLGVSFLVLPKYERIMQKY--NLLPE----KSMYDLVHGSSLW 240

  Fly   258 LLNSHAPLTTARPTVDAMVPVGGMHIYPPKPLPADMQALLDGATE-GAIFFSLGSNVQSKDMPVE 321
            :|.:...|...|||:..:|.|||:...|..|||.|:|..::||.| |.:..|.|:.|  |.:..:
Human   241 MLCTDVALEFPRPTLPNVVYVGGILTKPASPLPEDLQRWVNGANEHGFVLVSFGAGV--KYLSED 303

  Fly   322 MLRLFLQVFGSLKQRVLWKFEDESISQLPDNVMVRKWLPQADILAHRHVKVFITHGGLFGTQEGV 386
            :........|.|.|:|:|:|.......|.:|..:.:||||.|:|.|..:|.|::||||....|.:
Human   304 IANKLAGALGRLPQKVIWRFSGPKPKNLGNNTKLIEWLPQNDLLGHSKIKAFLSHGGLNSIFETI 368

  Fly   387 HYAVPMLGIPFYCDQHLNMNKAVLGGYAISLHFQSITEEILRHSLDQLIHNVTYKENVQRVSDIF 451
            ::.||::|||.:.|.:..|.:....|..|.|.::::||:.|..:|.::|:|.:|::..|::|:|.
Human   369 YHGVPVVGIPLFGDHYDTMTRVQAKGMGILLEWKTVTEKELYEALVKVINNPSYRQRAQKLSEIH 433

  Fly   452 RDRPLEPRKSAVYWIEYVIRHRGASHMRSAGLDLNWFQFYLLDVIAFVAIIALA 505
            :|:|..|....:|||:|:|||.||.|:|:|...:::.|::||| ||||.::..|
Human   434 KDQPGHPVNRTIYWIDYIIRHNGAHHLRAAVHQISFCQYFLLD-IAFVLLLGAA 486

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt49C1	NP_001036565.1	egt	22..504	CDD:223071	148/499 (30%)
		UDPGT	37..498	CDD:278624	141/478 (29%)
UGT8	NP_001121646.2	Glycosyltransferase_GTB-type	21..502	CDD:415824	148/499 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165150737
Domainoid	1	1.000	260	1.000	Domainoid score	I1978
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		mtm8543
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	8	7.740