Protein Alignment Ugt49C1 and UGT2B7

DIOPT Version :9

• Sequence 1: NP_001036565.1
• Gene: Ugt49C1 / 37421
• FlyBaseID: FBgn0034605
• Length: 530
• Species: Drosophila melanogaster
• Sequence 2: NP_001065.2
• Gene: UGT2B7 / 7364
• HGNCID: 12554
• Length: 529
• Species: Homo sapiens
• Alignment Length: 520
• Identity: 160/520 - (30%)
• Similarity: 252/520 - (48%)
• Gaps: 96/520 - (18%)

  Fly    37 SHFMMHTALIRELVESGHQVTMVTA--------------------FSLEKEQLGSNYTEILIE-- 79
            ||:|....::.||::.||:||::.:                    .||.|.:| .|:....|:
Human    34 SHWMNIKTILDELIQRGHEVTVLASSASILFDPNNSSALKIEIYPTSLTKTEL-ENFIMQQIKRW 97

  Fly    80 ---PVYDFW------HDVKLNFGAQHLFELTR------MTNYDFLKMLEIIGLKTTEHALRQPKV 129
               |...||      .::...||     ::||      ::|..|:|.::
Human    98 SDLPKDTFWLYFSQVQEIMSIFG-----DITRKFCKDVVSNKKFMKKVQ---------------- 141

  Fly   130 RSLIHAEQKEGVFDLLLAEQFYQEAFLALAHLYKIPVVTTSTL--GY--ENHMSQMMGLITPWSF 190
                     |..||::.|:..:..:.| ||.|:.||.|.:.:.  ||  |.|..   |.|.|.|:
Human   142 ---------ESRFDVIFADAIFPCSEL-LAELFNIPFVYSLSFSPGYTFEKHSG---GFIFPPSY 193

  Fly   191 VPHGFMPFTDRMSFLERVKNSYASFYEDMDRLLNYFPKMDAVAREFFGPVLTEVPKVKHMERQIS 255
            ||......||:|:|:|||||.....|.|....:....|.|    :|:..||.....:.....:..
Human   194 VPVVMSELTDQMTFMERVKNMIYVLYFDFWFEIFDMKKWD----QFYSEVLGRPTTLSETMGKAD 254

  Fly   256 VMLLNSH------APLTTARPTVDAMVPVGGMHIYPPKPLPADMQALLDGATE-GAIFFSLGSNV 313
            |.|:.:.      .||.   |.||.   |||:|..|.||||.:|:..:..:.| |.:.|||||.|
Human   255 VWLIRNSWNFQFPYPLL---PNVDF---VGGLHCKPAKPLPKEMEDFVQSSGENGVVVFSLGSMV 313

  Fly   314 QSKDMPVEMLRLFLQVFGSLKQRVLWKFEDESISQLPDNVMVRKWLPQADILAHRHVKVFITHGG 378
              .:|..|...:.......:.|:|||:|:......|..|..:.||:||.|:|.|...:.||||||
Human   314 --SNMTEERANVIASALAQIPQKVLWRFDGNKPDTLGLNTRLYKWIPQNDLLGHPKTRAFITHGG 376

  Fly   379 LFGTQEGVHYAVPMLGIPFYCDQHLNMNKAVLGGYAISLHFQSITEEILRHSLDQLIHNVTYKEN 443
            ..|..|.:::.:||:|||.:.||..|:......|.|:.:.|.:::...|.::|.::|::.:||||
Human   377 ANGIYEAIYHGIPMVGIPLFADQPDNIAHMKARGAAVRVDFNTMSSTDLLNALKRVINDPSYKEN 441

  Fly   444 VQRVSDIFRDRPLEPRKSAVYWIEYVIRHRGASHMRSAGLDLNWFQFYLLDVIAFVAIIALAGVM 508
            |.::|.|..|:|::|...||:|||:|:||:||.|:|.|..||.|||::.||||.|: ::.:|.|:
Human   442 VMKLSRIQHDQPVKPLDRAVFWIEFVMRHKGAKHLRVAAHDLTWFQYHSLDVIGFL-LVCVATVI 505

  Fly   509  508
            Human   506  505

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt49C1	NP_001036565.1	egt	22..504	CDD:223071	158/514 (31%)
		UDPGT	37..498	CDD:278624	157/508 (31%)
UGT2B7	NP_001065.2	UDPGT	24..525	CDD:278624	160/520 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165150707
Domainoid	1	1.000	260	1.000	Domainoid score	I1978
eggNOG	1	0.900	-	-		E33208_3BDT1
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	267	1.000	Inparanoid score	I3041
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		mtm8543
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	10	9.690