Protein Alignment Ugt49C1 and ugt1a1

DIOPT Version :9

• Sequence 1: NP_001036565.1
• Gene: Ugt49C1 / 37421
• FlyBaseID: FBgn0034605
• Length: 530
• Species: Drosophila melanogaster
• Sequence 2: NP_001032505.2
• Gene: ugt1a1 / 641488
• -ID: -
• Length: 525
• Species: Danio rerio
• Alignment Length: 560
• Identity: 174/560 - (31%)
• Similarity: 269/560 - (48%)
• Gaps: 84/560 - (15%)

  Fly     8 GLLLTGTLYSQLELAEGSKILAVYAFPGKSHFMMHTALIRELVESGHQ-VTMVTAFSLEKEQLGS 71
            |||....|:| .|..:..|:| |....| ||::....|:.||...||: |.:|...|:..::.|.
Zfish    10 GLLALLCLFS-FESVQAGKVL-VLPVDG-SHWLSMKILVEELSNRGHEMVVLVPETSILIKKSGK 71

  Fly    72 NYTEILIEPVYDFWHDVKLNFGAQHLFEL--------TRMTN--YDFLKMLEIIGL--KTTEHAL 124
            ..|:..  || .|.||..    |::|.|:        .::|:  .:|..:|:.:.:  ||.|..|
Zfish    72 YSTKTY--PV-SFTHDDL----AENLKEIQNSALEKAPKLTDIVVNFRNLLQFLTMQSKTCEGLL 129

  Fly   125 -RQPKVRSLIHAEQKEGVFDLLLAEQFYQEAFLALAHLYKIPVVTTSTLGYENHMSQMMGLI--- 185
             .:|.::||     :|..||.:|.:.|.....: :|..:.||.|            ..:.||
Zfish   130 YNEPLMKSL-----REMGFDAMLTDPFLPCGTI-IADSFSIPAV------------YFLRLIPCR 176

  Fly   186 ---------TPWSFVPHGFMPFTDRMSFLERVKNSY---------ASFYEDMDRLLNYFPKMDAV 232
                     :|.||:|.....|||:|:|.:|:.|:.         .|.||..|.|.:.:.:.:..
Zfish   177 LDEAAAQCPSPPSFMPRYSSGFTDKMTFPQRLVNTLLTVVEGFLCRSMYESADELASKYLQKETT 241

  Fly   233 AREFFGPVLTEVPKVKHMERQISVMLLNSHAPLTTARPTVDAMVPVGGMHIYPPKPLPADMQALL 297
            ..|..|              ..:|.||.........||.:..||.:||::.....||..:::..:
Zfish   242 YAELLG--------------HGAVWLLRYDFAFEFPRPQMPNMVQIGGINCVKRAPLTKELEEFV 292

  Fly   298 DGATE-GAIFFSLGSNVQSKDMPVEMLRLFLQVFGSLKQRVLWKFEDESISQLPDNVMVRKWLPQ 361
            :|:.| |.:.|:|||.|  ..:|....|.|.:.|..:.|||||::........|.||.:.|||||
Zfish   293 NGSGEHGFVVFTLGSMV--SQLPEAKAREFFEAFRQIPQRVLWRYTGPVPENAPKNVKLMKWLPQ 355

  Fly   362 ADILAHRHVKVFITHGGLFGTQEGVHYAVPMLGIPFYCDQHLNMNKAVLGGYAISLHFQSITEEI 426
            .|:|.|..|:.|:||||..|..||:...|||:.:|.:.||..|..:.|..|.|.||....:|.|.
Zfish   356 NDLLGHPKVRAFVTHGGSHGIYEGICNGVPMVMLPLFGDQGDNAQRLVSRGVAESLTIYDVTSEK 420

  Fly   427 LRHSLDQLIHNVTYKENVQRVSDIFRDRPLEPRKSAVYWIEYVIRHRGASHMRSAGLDLNWFQFY 491
            |..:|.::|::.:|||.:.::|.|.||||:||...||:|.|:|:||:||.|:|.|..||||.|::
Zfish   421 LLVALKKVINDKSYKEKMMKLSAIHRDRPIEPLDLAVFWTEFVMRHKGAEHLRPAAHDLNWIQYH 485

  Fly   492 LLDVIAFVAIIAL----AGVMALSLAIRLLMGSNKKHRKA 527
            .||||.|:.:|.|    ..|.:.....|.....::|.:||
Zfish   486 SLDVIGFLLLILLTVIFVTVKSCMFCFRKCFKKSQKKKKA 525

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt49C1	NP_001036565.1	egt	22..504	CDD:223071	162/517 (31%)
		UDPGT	37..498	CDD:278624	156/496 (31%)
ugt1a1	NP_001032505.2	UDPGT	26..513	CDD:278624	164/529 (31%)
		egt	<264..502	CDD:223071	97/239 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R8488
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.030