Protein Alignment Ugt49C1 and ugt1ab

DIOPT Version :9

• Sequence 1: NP_001036565.1
• Gene: Ugt49C1 / 37421
• FlyBaseID: FBgn0034605
• Length: 530
• Species: Drosophila melanogaster
• Sequence 2: NP_998587.2
• Gene: ugt1ab / 406731
• ZFINID: ZDB-GENE-040426-2762
• Length: 536
• Species: Danio rerio
• Alignment Length: 552
• Identity: 166/552 - (30%)
• Similarity: 262/552 - (47%)
• Gaps: 68/552 - (12%)

  Fly     8 GLLLTGTLYSQLELAEGSKILAVYAFPGKSHFMMHTALIRELVESGHQVTMV---TAFSLEKEQL 69
            ||.....|:|. |..:..|:| |....| ||::....|:.|:...||::.::   |:..:.|
Zfish    21 GLFAFLCLFSS-ESVQAGKVL-VMPVDG-SHWLSMKILVEEMSSRGHEMVVLVPETSILIGK--- 79

  Fly    70 GSNYTEILIEPVYDFWHDVKLNFGAQHLFELTRMTNYDFL-KMLEIIG------------LKTTE 121
            ..|:|.......|.|   .:||....|:    |.|..:.. :.::|:|            :|..|
Zfish    80 SGNFTTKSFRVPYSF---DELNAHVDHI----RKTAIEKAPRFIDIVGALGNLIQFTNMQVKACE 137

  Fly   122 HAL-RQPKVRSLIHAEQKEGVFDLLLAEQFYQEAFLALAHLYKIPVVTTSTLGYENHMSQMMGLI 185
            ..| .:|.::||     ::..||.||.:.|. .....:|..:.||.| ....|....:.:.....
Zfish   138 GLLYDEPLMKSL-----RDMKFDALLTDPFL-PCGSVIADYFSIPAV-YFLRGIPCRLDEAAAQC 195

  Fly   186 -TPWSFVPHGFMPFTDRMSFLERVKNSYASFYE---------DMDRLLNYFPKMDAVAREFFGPV 240
             :|.||:|..|..:||:|:|.:|:.|::.:.:|         ..|.|...:.|.|....|..|
Zfish   196 PSPPSFIPRFFTGYTDKMTFPQRMINTFMTVFEKYLCHQLFASFDELATRYLKKDTSYAELLG-- 258

  Fly   241 LTEVPKVKHMERQISVMLLNSHAPLTTARPTVDAMVPVGGMHIYPPKPLPADMQALLDGATE-GA 304
                        ..:|.||.........:|.:..||.:||::.....||..:::..::|:.| |.
Zfish   259 ------------HGAVWLLRYDFSFEYPKPQMPNMVQIGGINCAKRAPLTKELEEFVNGSGEHGF 311

  Fly   305 IFFSLGSNVQSKDMPVEMLRLFLQVFGSLKQRVLWKFEDESISQLPDNVMVRKWLPQADILAHRH 369
            :.|:|||.|  ..:|....|.|.:.|..:.|||||::........|.||.:.|||||.|:|.|..
Zfish   312 VVFTLGSMV--SQLPEAKAREFFEAFRQIPQRVLWRYTGPVPENAPKNVKLMKWLPQNDLLGHPK 374

  Fly   370 VKVFITHGGLFGTQEGVHYAVPMLGIPFYCDQHLNMNKAVLGGYAISLHFQSITEEILRHSLDQL 434
            |:.|:||||..|..||:...|||:.:|.:.||..|..:.|..|.|.||....:|.|.|..:|.::
Zfish   375 VRAFVTHGGSHGIYEGICNGVPMVMLPLFGDQGDNAQRLVSRGVAESLTIYDVTSEKLLVALKKV 439

  Fly   435 IHNVTYKENVQRVSDIFRDRPLEPRKSAVYWIEYVIRHRGASHMRSAGLDLNWFQFYLLDVIAFV 499
            |::.:|||.:.::|.|.||||:||...||:|.|:|:||:||.|:|.|..||||.|::.||||.|:
Zfish   440 INDKSYKEKMMKLSAIHRDRPIEPLDLAVFWTEFVMRHKGAEHLRPAAHDLNWIQYHSLDVIGFL 504

  Fly   500 AIIAL----AGVMALSLAIRLLMGSNKKHRKA 527
            .:|.|    ..|.:.....|.....::|.:||
Zfish   505 LLILLTVIFVTVKSCMFCFRKCFKKSQKKKKA 536

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt49C1	NP_001036565.1	egt	22..504	CDD:223071	155/509 (30%)
		UDPGT	37..498	CDD:278624	149/488 (31%)
ugt1ab	NP_998587.2	UDPGT	37..524	CDD:278624	157/521 (30%)
		egt	<279..513	CDD:223071	95/235 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	252	1.000	Domainoid score	I2043
eggNOG	1	0.900	-	-		E33208_3BDT1
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	252	1.000	Inparanoid score	I3189
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		mtm6444
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	9	8.760