Protein Alignment Ugt49C1 and Ugt1a2

DIOPT Version :10

• Sequence 1: NP_611564.2
• Gene: Ugt49C1 / 37421
• FlyBaseID: FBgn0034605
• Length: 530
• Species: Drosophila melanogaster
• Sequence 2: NP_958826.1
• Gene: Ugt1a2 / 396527
• RGDID: 1549741
• Length: 533
• Species: Rattus norvegicus
• Alignment Length: 570
• Identity: 170/570 - (29%)
• Similarity: 261/570 - (45%)
• Gaps: 91/570 - (15%)

  Fly     4 PL--LFGLLLTGTLYSQLELAEGSKILAVYAFPGKSHFMMHTALIRELVESGHQVTMVT------ 60
            ||  |.||||   |...|..|||.|:| |:...| ||::....::|||...|||..::.
  Rat     8 PLRGLSGLLL---LLCALPWAEGGKVL-VFPMEG-SHWLSMRDVVRELHARGHQAVVLAPEVTVH 67

  Fly    61 ------------AFSLEKEQLGSNYTEILIEPVYDFWHDVKLNFGAQHLFELTRMTNYDFLKMLE 113
                        ||...||:.   ..|||        .:.|..|..||..:....|.....|..:
  Rat    68 MKGEDFFTLQTYAFPYTKEEY---QREIL--------GNAKKGFEPQHFVKTFFETMASIKKFFD 121

  Fly   114 IIGLKTTEHALRQPKVRSLIH-----AEQKEGVFDLLLAEQFYQEAFLALAHLYKIPVV---TTS 170
                      |......:|:|     .:.....||::|.:..:....| ||...:||.|   .:.
  Rat   122 ----------LYANSCAALLHNKTLIQQLNSSSFDVVLTDPVFPCGAL-LAKYLQIPAVFFLRSV 175

  Fly   171 TLGYENHMSQMMGLITPWSFVPHGFMPFTDRMSFLERVKNSYASFYEDMDRLLNYFPKMDAVARE 235
            ..|.:...:|..   .|.|::|:.....:|.|:||:||||.....      .|.|...:.....|
  Rat   176 PCGIDYEATQCP---KPSSYIPNLLTMLSDHMTFLQRVKNMLYPL------TLKYICHLSITPYE 231

  Fly   236 FFGPVLTEVPKVKHMERQISVMLLNSHAPL---------TTARPTVDAMVPVGGMHIYPPKPLPA 291
            .....|        ::|::|::.:.|||.:         ...||.:..||.:||::....|||..
  Rat   232 SLASEL--------LQREMSLVEVLSHASVWLFRGDFVFDYPRPIMPNMVFIGGINCVIKKPLSQ 288

  Fly   292 DMQALLDGATE-GAIFFSLGSNVQSKDMPVEMLRLFLQVFGSLKQRVLWKFEDESISQLPDNVMV 355
            :.:|.::.:.| |.:.|||||.|  .::|.:......:..|.:.|.|||::.....|.|..|.::
  Rat   289 EFEAYVNASGEHGIVVFSLGSMV--SEIPEKKAMEIAEALGRIPQTVLWRYTGTRPSNLAKNTIL 351

  Fly   356 RKWLPQADILAHRHVKVFITHGGLFGTQEGVHYAVPMLGIPFYCDQHLNMNKAVLGGYAISLHFQ 420
            .|||||.|:|.|...:.||||.|..|..||:...|||:.:|.:.||..|..:....|..::|:..
  Rat   352 VKWLPQNDLLGHPKARAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVL 416

  Fly   421 SITEEILRHSLDQLIHNVTYKENVQRVSDIFRDRPLEPRKSAVYWIEYVIRHRGASHMRSAGLDL 485
            .:|.:.|.::|..:|:|.:||||:.|:|.:.:|||:||...||:|:|||:||:||.|:|.|..||
  Rat   417 EMTADDLENALKTVINNKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDL 481

  Fly   486 NWFQFYLLDVIAFVAIIALAGVM----ALSLAIRLLMGSN---KKHRKAK 528
            .|:|::.||||.|:..|.|..|.    :.:...|...|..   ||..|:|
  Rat   482 TWYQYHSLDVIGFLLAIVLTVVFIVYKSCAYGCRKCFGGKGRVKKSHKSK 531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt49C1	NP_611564.2	Glycosyltransferase_GTB-type	37..498	CDD:471961	144/496 (29%)
Ugt1a2	NP_958826.1	UDPGT	28..524	CDD:278624	154/538 (29%)