DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt49C1 and Ugt317A1

DIOPT Version :9

Sequence 1:	NP_001036565.1	Gene:	Ugt49C1 / 37421	FlyBaseID:	FBgn0034605	Length:	530	Species:	Drosophila melanogaster
Sequence 2:	NP_001286734.1	Gene:	Ugt317A1 / 37590	FlyBaseID:	FBgn0040091	Length:	529	Species:	Drosophila melanogaster

Alignment Length:	519	Identity:	160/519 - (30%)
Similarity:	272/519 - (52%)	Gaps:	17/519 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 ELAEGSKILAVYAFPGKSHFMMHTALIRELVESGHQVTMVTAFSLEKEQLGSNYTEILIEPVYDF 84
            ::::.:|||.::....:.||.:...|:.||....|.:.:.|...| .|.| .|.|| .:...:.|
  Fly    20 QISQAAKILVLFPHVNEGHFAVMRTLVTELANREHTIEVYTGHGL-GESL-DNVTE-TVTAEFPF 81

  Fly    85 WHDVKLNFGAQ-HLFELTRMTNYDFLKMLEIIGLKTTEHALRQPKVRSLIHAEQKEGVFDLLLAE 148
            |.:::.....: :|.:|..:......:.|..:|.:..:|.|.|..::.|:.....|..||::|.:
  Fly    82 WSELQKQAAPKGNLADLGLLPIEKLRQSLASVGARALDHFLAQEPIQKLLKMSYLEFDFDVILVD 146

  Fly   149 QFYQEAFLALAHLYKIPVVTTSTLGYENHMSQMMGLITPWSFVPHGFMPFTDRMSFLERVKNSYA 213
            .||.||.|||..|::.|||...:..:.|:|..:...:.|.:..|..|......|||..|:.|...
  Fly   147 YFYTEALLALGALHQRPVVGIISTDFGNYMDAVQEALVPAACSPIDFERDQPEMSFSVRLGNIRT 211

  Fly   214 SFYEDMDRLLNYFPKMDAVAREFFGPVLTEVPKVKHMERQISVMLLNSHAPLTTARPTVDAMVPV 278
            ........:.:::...:.:..::| .:.:.:|:::  ..|:||:|||||.||.|.:.::..::|.
  Fly   212 CIARRKQFIKDHYGGQEQLVTKYF-QLQSSIPELQ--ASQLSVLLLNSHVPLITPKVSIQQIIPA 273

  Fly   279 GGMHIYPPKPLPADMQALLDGATEGAIFFSLGSNVQSKDMPVEMLRLFLQVFGSLKQRVLWKFED 343
            ||:||..||.||.:::..|:.|..|||:..||:......:|.|.|......|.:.||.::|...|
  Fly   274 GGLHIRGPKELPWNVKRFLEEARPGAIYVQLGNEQACGQLPKEKLDTLFAFFSARKQSIIWTCHD 338

  Fly   344 -ESISQLPDNVMVRKWLPQADILAHRHVKVFITHGGLFGTQEGVHYAVPMLGIPFYCDQHLNMNK 407
             :::..||.|||::..:||.|||||..||.|:|:|.|...|||:...||:||:|.:..:..||..
  Fly   339 VKTLEGLPKNVMIQHAVPQIDILAHPRVKAFLTNGDLLNLQEGIMRNVPILGLPLFQHEARNMEL 403

  Fly   408 AVLGGYAISLHFQSITEEILRHSLDQLIHNVTYKENVQRVSDIFRDRPLEPRKSAVYWIEYVIRH 472
            ||..|..:.|...::|.|.|..::|:|:....::..::.||..||||||....||::|:.||.||
  Fly   404 AVRLGVGLQLEEGNVTTESLNWAVDRLLLESHFQLTIRDVSLEFRDRPLGALASALFWVNYVARH 468

  Fly   473 RGASHMRSAGLDLNWFQFYLLDVIAFVAIIALAGVMALSLAIRLLMGS----NKKH--RKAKQN 530
            :|.|.:|:.|:.::..|.:|.|:..|.|.||   .:.:||.:.|..|.    |||:  :..|.|
  Fly   469 KGGSALRTRGIGISSCQLHLFDLFVFYAGIA---TLVVSLLVALSFGGFYIWNKKNNSKSTKVN 529

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt49C1	NP_001036565.1	egt	22..504	CDD:223071	150/483 (31%)
Ugt49C1	NP_001036565.1	UDPGT	37..498	CDD:278624	144/462 (31%)
Ugt317A1	NP_001286734.1	Glycosyltransferase_GTB_type	22..477	CDD:299143	143/460 (31%)
Ugt317A1	NP_001286734.1	UDPGT	25..514	CDD:278624	155/497 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	76	1.000	Domainoid score	I3136
eggNOG	1	0.900	-	-		E33208_3BDT1
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	89	1.000	Inparanoid score	I2281
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR48043
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.960