Protein Alignment Ugt49C1 and Ugt2b37

DIOPT Version :10

• Sequence 1: NP_611564.2
• Gene: Ugt49C1 / 37421
• FlyBaseID: FBgn0034605
• Length: 530
• Species: Drosophila melanogaster
• Sequence 2: NP_001007265.4
• Gene: Ugt2b37 / 29623
• RGDID: 3937
• Length: 530
• Species: Rattus norvegicus
• Alignment Length: 554
• Identity: 161/554 - (29%)
• Similarity: 278/554 - (50%)
• Gaps: 62/554 - (11%)

  Fly     6 LFGLLLTGTLYSQLELAEGSKILAVYAFPGK-SHFMMHTALIRELVESGHQVTMV--TAF----- 62
            :|.|||....:. |..|:..|:|   .:|.: ||:|....::.|||:.||:||::  :|:
  Rat     6 IFALLLLQISFC-LRSAKCGKVL---VWPMEFSHWMNIKTILDELVQRGHEVTVLKPSAYYVLDP 66

  Fly    63 -------------SLEKEQLGSNYTEILIEPVYDFWHDVKLNFGAQHLFELTRMTNYDFLKMLEI 114
                         |:.|::|...:.:::     |.|           .:||.|.|...|..:|:.
  Rat    67 KKSPDLKFETFPTSVSKDELEKYFIKLV-----DAW-----------TYELQRDTCLSFSPLLQN 115

  Fly   115 IGLKTTEHAL---RQPKVRSLIHAEQKEGVFDLLLAEQFYQEAFLALAHLYKIPVVTTSTLGYEN 176
            :..:.:::.|   :.......:.|:.:|..||:||::.......| :|.:..||.:.:......:
  Rat   116 MMDEFSDYYLSVCKDAVSNKQLMAKLQESKFDVLLSDPVAACGEL-IAEVLHIPFLYSLRASPGH 179

  Fly   177 HMSQMMG-LITPWSFVPHGFMPFTDRMSFLERVKNS----YASFYEDMDRLLNYFPKMDAVAREF 236
            .:.:..| .|.|.|:||........:|:|::||||.    |..|:..|....|:.|        |
  Rat   180 KIEKSSGRFILPPSYVPVILSGLGGQMTFIDRVKNMICMLYFDFWFHMFNAKNWDP--------F 236

  Fly   237 FGPVLTEVPKVKHMERQISVMLLNSHAPLTTARPTVDAMVPVGGMHIYPPKPLPADMQALLDGAT 301
            :..:|.....:.....:..:.|:.|:..|....||:..:..:||:...|.||||.|::..:..:.
  Rat   237 YTEILGRPTTLAETMGKAEMWLIRSYWDLEFPHPTLPNVDYIGGLQCKPAKPLPKDIEDFVQSSG 301

  Fly   302 E-GAIFFSLGSNVQSKDMPVEMLRLFLQVFGSLKQRVLWKFEDESISQLPDNVMVRKWLPQADIL 365
            | |.:.|||||.|.|  |..|...........:.|:|||||:.:..:.|..|..|.|||||.|:|
  Rat   302 EHGVVVFSLGSMVSS--MTEEKANAVAWALAQIPQKVLWKFDGKIPATLGPNTRVYKWLPQNDLL 364

  Fly   366 AHRHVKVFITHGGLFGTQEGVHYAVPMLGIPFYCDQHLNMNKAVLGGYAISLHFQSITEEILRHS 430
            .|...|.|:||||..|..|.:::.:||:|||.:.:||.|:...|..|.|::|:.:::::..|.::
  Rat   365 GHPKTKAFVTHGGANGVYEAIYHGIPMIGIPMFGEQHDNIAHMVAKGAAVTLNIRTMSKSDLFNA 429

  Fly   431 LDQLIHNVTYKENVQRVSDIFRDRPLEPRKSAVYWIEYVIRHRGASHMRSAGLDLNWFQFYLLDV 495
            |.::|:|..||:|...:|.|..|:|::|...|::|||||:||:.|.|:|..|.:|.|:|::.|||
  Rat   430 LKEVINNPFYKKNAMWLSTIHHDQPMKPLDKAIFWIEYVMRHKRAKHLRPLGHNLPWYQYHSLDV 494

  Fly   496 IAF-VAIIALAGVMALSLAIRLLMGSNKKHRKAK 528
            |.| :|.:|:...:|:...:.:.....||.:|.|
  Rat   495 IGFLLACLAVIAALAVKCFLFIYRFFAKKQKKMK 528

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt49C1	NP_611564.2	Glycosyltransferase_GTB-type	37..498	CDD:471961	144/489 (29%)
Ugt2b37	NP_001007265.4	UDPGT	24..527	CDD:278624	153/532 (29%)