Protein Alignment Ugt49C1 and ugt-8

DIOPT Version :10

• Sequence 1: NP_611564.2
• Gene: Ugt49C1 / 37421
• FlyBaseID: FBgn0034605
• Length: 530
• Species: Drosophila melanogaster
• Sequence 2: NP_504315.1
• Gene: ugt-8 / 186768
• WormBaseID: WBGene00019234
• Length: 531
• Species: Caenorhabditis elegans
• Alignment Length: 549
• Identity: 133/549 - (24%)
• Similarity: 229/549 - (41%)
• Gaps: 69/549 - (12%)

  Fly     5 LLFGLLLTGTLYSQLELAEGSKILAVYAFPGKSHFMMHTALIRELVESGHQVTMVTAFSLEKEQ- 68
            ||..||:.|::..:       .||......|.||....:.:...:.:.||.||:...|.:..:.
 Worm     6 LLSILLVLGSVSCK-------NILIFNPIFGLSHVKFISKMANIIADHGHNVTLFQPFHIALKNT 63

  Fly    69 ---LGSNYTEIL--IEPVYD------------FWHDVKLNFGAQHLFELTRMTNYDFLKMLEIIG 116
               :.:.|.||:  ....||            ||....:|......|.:.:....:|
 Worm    64 EGLIKNKYIEIINYYPDHYDELLKTETATFPAFWDSHLMNNPVLSAFMIPKAIAGEF-------- 120

  Fly   117 LKTTEHALRQPKVRSLIHAEQKEGVFDLLLAEQFYQEAFLALAHLYKIPVVTTSTLGYENHMSQM 181
             :.|...|.:.||..   .:.|...||::::|.| :...:.:||:..:|.:...:.......:.:
 Worm   121 -ERTATQLLKDKVAL---DDLKSRNFDVIISETF-ELTGMYIAHMLNVPCIPVWSAVRFTIFNNI 180

  Fly   182 MGLITPWSFVPHGFMPFTDRMSFLERVKNSYASFY-----EDMDRLLNYFPKMDAVAREFFGPVL 241
            .|..:...:....|........|::|:.:.|.:|:     :.|.:..|.|.: .||.|
 Worm   181 FGQPSSLGYSQQPFSKLAPEAGFIDRLNDVYRNFFFTITMDGMGQYQNDFIE-KAVGR------- 237

  Fly   242 TEVPKVKHMERQISVMLLNSHAPLTTARPTVDAMVPVGGM--------HIYPPKPLPADMQALLD 298
             .:|..|.:.::..|...||:..|..|.||...:|.:||.        |:   .||| |..|.:.
 Worm   238 -PLPYWKDLIKEAPVYFTNSNEYLDFAVPTTATIVHIGGFTMDLEKMKHV---DPLP-DKYAKIL 297

  Fly   299 GATEGAIFFSLGSNVQSKDMPVEMLRLFLQVFGSLKQ-RVLWKFEDESI---SQLPDNVMVRKWL 359
            ...|..:..|.||.::|..||.......:::|.||.. ..:||:|.:.:   .:||.||.::||:
 Worm   298 EERESTVLISFGSVIRSYQMPDNFKAGIIKMFESLPDVTFIWKYERDDVEFQKKLPKNVHLKKWV 362

  Fly   360 PQADILAHRHVKVFITHGGLFGTQEGVHYAVPMLGIPFYCDQHLNMNKAVLGGYAISL-HFQSIT 423
            ||..:||...||:|:|||||..|.|..:...|.|.:|.:.||..|.|.....|.|||. .|:...
 Worm   363 PQHSLLADNRVKLFVTHGGLGSTMEVAYTGKPALMVPIFGDQPENANMLARHGGAISYDKFELAD 427

  Fly   424 EEILRHSLDQLIHNVTYKENVQRVSDIFRDRPLEPRKSAVYWIEYVIRHRGASHMRSAGLDLNWF 488
            .|.|..::..::.|..|.:|.|.:..:...:|::|:.:.:..:|:.:..........|...:...
 Worm   428 GEKLAITIRDMVRNPKYNKNAQELLKVLSHQPIDPKLNLMKHLEFAMEFPNLRSQVPAINQMGLI 492

  Fly   489 QFYLLDVIAFVAIIALAGVMALSLAIRLL 517
            ..|.||||.|:::|.:..|......|.||
 Worm   493 AHYYLDVIFFLSLIFILTVYLTFKIISLL 521

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt49C1	NP_611564.2	Glycosyltransferase_GTB-type	37..498	CDD:471961	119/496 (24%)
ugt-8	NP_504315.1	GT1_Gtf-like	20..457	CDD:340817	113/462 (24%)