Protein Alignment Ugt49C1 and ugt-2

DIOPT Version :10

• Sequence 1: NP_611564.2
• Gene: Ugt49C1 / 37421
• FlyBaseID: FBgn0034605
• Length: 530
• Species: Drosophila melanogaster
• Sequence 2: NP_505672.2
• Gene: ugt-2 / 179450
• WormBaseID: WBGene00007073
• Length: 531
• Species: Caenorhabditis elegans
• Alignment Length: 609
• Identity: 128/609 - (21%)
• Similarity: 226/609 - (37%)
• Gaps: 173/609 - (28%)

  Fly     5 LLFGLLLTGTLYSQLELAEGSKILAVYAFPGKSHFMMHTALIRELVESGHQVTMVTAFSLEKEQL 69
            |.|.|......|:.|.:|      .|:   |.||......:...|....|.||::..:
 Worm     9 LFFALYCNVLAYNYLVVA------PVF---GYSHMKFMNKVADTLANGKHNVTLLQTY------- 57

  Fly    70 GSNYTEILIEPVYDFWHDVKLNFGAQHLFELTRMTNYDFLKMLEIIGLKTTEHALRQPKVRSLIH 134
                       :|:.|..:::            :.|    |.:|||....:|:....
 Worm    58 -----------IYEHWGKIRI------------VKN----KNIEIIDYHNSENVPSN-------- 87

  Fly   135 AEQKEGVFDLLLAEQFYQEAFLALAHLYKIPVVTTSTLGYENHM--SQMMGLITPWSFVPHGFMP 197
             ||....|      :|:                      ::|.:  :.:.|.:.|...:.:.|.|
 Worm    88 -EQSASAF------KFF----------------------WDNEIVNNPITGAMAPMFILYNEFKP 123

  Fly   198 FTDRM---------------------SF------------------LERVKNSYASFYEDMDRLL 223
            ..||:                     ||                  ...:||...|.......||
 Worm   124 MCDRILTDKELHQWILSNKFDGYVAESFDFCSLYLGDHLKLNLLPMFSTIKNVPGSHAIGEPSLL 188

  Fly   224 NYFPKM---------------DAVA----------------REFFGPVLTEVPKVKHMERQISVM 257
            ||.|.:               |..|                |:.:..:..:|...:.:.:..:..
 Worm   189 NYAPSLYTNFGSDQTVWDRIQDITAFTSFHYAFSNLFERQYRQAYDLLNGDVRTWREILQTATYF 253

  Fly   258 LLNSHAPLTTARPTVDAMVPVGGMHIYPPKPLP--ADMQALLDGATEGAIFFSLGSNVQSKDMPV 320
            ..|::..:..|.||::..|.:||..|.||..|.  .:...||| ..:..:..|.|:.|||.|||.
 Worm   254 FYNNNPYIGFAMPTLEKSVEIGGFTIDPPHDLSLNEEFDKLLD-LRKSTVLISFGTVVQSADMPE 317

  Fly   321 EMLRLFLQVFGSLKQRV-LWKF--EDESISQ-LPDNVMVRKWLPQADILAHRHVKVFITHGGLFG 381
            ......:::|..|.... :||:  ||...|: |.:||.::||:||..:||...:.:|||||||..
 Worm   318 NFKSGLIKMFAKLPDTTFIWKYEVEDAEFSKTLSENVFLKKWIPQPALLADPRLNLFITHGGLGS 382

  Fly   382 TQEGVHYAVPMLGIPFYCDQHLNMNKAVLGGYAISL------HFQSITEEILRHSLDQLIHNVTY 440
            |.|..:...|.|.||.:.||.||.......|.|||.      :::.:||     ::.:.|.|..|
 Worm   383 TLEVAYAGKPSLMIPIFGDQMLNAKMLSRHGGAISYDKYELENYEKLTE-----TVKEAISNKEY 442

  Fly   441 KENVQRVSDIFRDRPLEPRKSAVYWIEYVIRHRGASHMRSAGLDLNWFQFYLLDVIAFVAIIALA 505
            .:....:::|..::|::|:::.:...|:..:......:....:..|:.::|:||..|.:.|..|:
 Worm   443 NKKALLLAEILHNQPIDPKQNLLKHAEFTAKFGRVHALEPYSVHYNFIKYYMLDAYAIIIIFFLS 507

  Fly   506 GVMALSLAIRLLMGSNKKHRKAKQ 529
            .:..|:|.|:.:.   :|..|:|:
 Worm   508 ILYVLNLIIKFVY---RKIFKSKR 528

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt49C1	NP_611564.2	Glycosyltransferase_GTB-type	37..498	CDD:471961	111/544 (20%)
ugt-2	NP_505672.2	GT1_Gtf-like	24..453	CDD:340817	106/514 (21%)