Protein Alignment Ugt49C1 and Ugt1a6

DIOPT Version :10

• Sequence 1: NP_611564.2
• Gene: Ugt49C1 / 37421
• FlyBaseID: FBgn0034605
• Length: 530
• Species: Drosophila melanogaster
• Sequence 2: NP_476446.2
• Gene: Ugt1a6 / 113992
• RGDID: 620949
• Length: 530
• Species: Rattus norvegicus
• Alignment Length: 578
• Identity: 158/578 - (27%)
• Similarity: 255/578 - (44%)
• Gaps: 117/578 - (20%)

  Fly     3 FPLLFGLLLTGTLYSQLELAEGSKILAVYAFP-GKSHFMMHTALIRELVESGHQVTMV------- 59
            |.:|:|.:|            |.|:|.|   | ..||::....::..|.|.||.:.::
  Rat    16 FLVLWGSVL------------GDKLLVV---PQDGSHWLSMKEIVEHLSERGHDIVVLVPEVNLL 65

  Fly    60 -------------TAFSLEK-----EQLGSNY---TEILIEPVYDFWHDV----KLNFGAQHLFE 99
                         ..::||:     ...|:|:   :..|:.|:.::.:::    ...|..|.|
  Rat    66 LGESKYYRRKSFPVPYNLEELRTRYRSFGNNHFAASSPLMAPLREYRNNMIVIDMCFFSCQSL-- 128

  Fly   100 LTRMTNYDFLKMLEIIGLKTTEHALRQPKVRSLIHAEQKEGVFDLLLAEQFYQEAFLALAHLYKI 164
            |.......||                            :|..||.|..:. .....:.||...|:
  Rat   129 LKDSATLSFL----------------------------RENQFDALFTDP-AMPCGVILAEYLKL 164

  Fly   165 PVVTTSTLGYENHMSQMMGLI-TPWSFVPHGFMPFTDRMSFLERVKNSYASFYEDMDRLLNY--- 225
            |.|.... |:...:..|:|.. :|.|:||..:..|:|.|:|.:|:.|..|:..|      ||
  Rat   165 PSVYLFR-GFPCSLEHMLGQSPSPVSYVPRFYTKFSDHMTFPQRLANFIANILE------NYLYH 222

  Fly   226 --FPKMDAVA-----REFFGPVLTEVPKVKHMERQISVMLLNSHAPLTTARPTVDAMVPVGGMHI 283
              :.|.:.:|     |:...|.|          .|.|:.||.........||.:..|:.:||.:.
  Rat   223 CLYSKYEILASDLLKRDVSLPAL----------HQNSLWLLRYDFVFEYPRPVMPNMIFIGGTNC 277

  Fly   284 YPPKPLPADMQALLDGATE-GAIFFSLGSNVQSKDMPVEMLRLFLQVFGSLKQRVLWKFEDESIS 347
            .....|..:.:|.::.:.| |.:.|||||.|  .::|.:......:..|.:.|.|||::.....|
  Rat   278 KKKGNLSQEFEAYVNASGEHGIVVFSLGSMV--SEIPEKKAMEIAEALGRIPQTVLWRYTGTRPS 340

  Fly   348 QLPDNVMVRKWLPQADILAHRHVKVFITHGGLFGTQEGVHYAVPMLGIPFYCDQHLNMNKAVLGG 412
            .|..|.::.|||||.|:|.|...:.||||.|..|..||:...|||:.:|.:.||..|..:....|
  Rat   341 NLAKNTILVKWLPQNDLLGHPKARAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRG 405

  Fly   413 YAISLHFQSITEEILRHSLDQLIHNVTYKENVQRVSDIFRDRPLEPRKSAVYWIEYVIRHRGASH 477
            ..::|:...:|.:.|.::|..:|:|.:||||:.|:|.:.:|||:||...||:|:|||:||:||.|
  Rat   406 AGVTLNVLEMTADDLENALKTVINNKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPH 470

  Fly   478 MRSAGLDLNWFQFYLLDVIAFVAIIALAGVM----ALSLAIRLLMGSN---KKHRKAK 528
            :|.|..||.|:|::.||||.|:..|.|..|.    :.:...|...|..   ||..|:|
  Rat   471 LRPAAHDLTWYQYHSLDVIGFLLAIVLTVVFIVYKSCAYGCRKCFGGKGRVKKSHKSK 528

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt49C1	NP_611564.2	Glycosyltransferase_GTB-type	37..498	CDD:471961	139/504 (28%)
Ugt1a6	NP_476446.2	UDPGT	26..521	CDD:278624	149/547 (27%)