Protein Alignment Ugt49C1 and Ugt3a1

DIOPT Version :9

• Sequence 1: NP_001036565.1
• Gene: Ugt49C1 / 37421
• FlyBaseID: FBgn0034605
• Length: 530
• Species: Drosophila melanogaster
• Sequence 2: NP_997099.2
• Gene: Ugt3a1 / 105887
• MGIID: 2146055
• Length: 523
• Species: Mus musculus
• Alignment Length: 553
• Identity: 154/553 - (27%)
• Similarity: 250/553 - (45%)
• Gaps: 71/553 - (12%)

  Fly    10 LLTGTLYSQLELAEGSKILAVYAFPGKSHFMMHTALIRELVESGHQVTM-------VTAFSLEKE 67
            ||......::.|.|.:|||.:... ..||:::...:.:.|...||.|..       :..|..|
Mouse     8 LLVSFFLLEVLLLEAAKILTISTL-SASHYILMNRVSQILQGGGHDVIKLLYEGGDIPDFRKE-- 69

  Fly    68 QLGSNYTEI---LIE----PVYDFWHDV--KLNFGAQHLFELTRMTNYDFLKMLEIIGLKTTEHA 123
              .|:|..|   |.|    ...:.||.:  :..:|......|.::..| |..:        ..|.
Mouse    70 --NSSYQVINWRLPEDQQKTFENRWHRLIDEYAYGRSKYHTLLKIHQY-FADL--------CSHL 123

  Fly   124 LRQPKVRSLIHAEQKEGVFDLLLAEQFYQEAFLALAHLYKIPVVTTSTLGYE-NHMSQMMGL-IT 186
            |.:..:..|:   |||. |||:|.:.....:||.:..|.|..|   |.|.:: ::|.  .|| ..
Mouse   124 LSRKDIMELL---QKEN-FDLVLLDSMDLCSFLIVEKLGKRFV---SFLPFQFSYMD--FGLPNA 179

  Fly   187 PWSFVPHGFMPFTDRMSFLERVKNSYASFYEDMDRLLNYFPKMDAVAREFFG----PVLTEVPKV 247
            |.|:.|......||:|.|..|||| ...|:....:..:.|.:.....:|.|.    |||::
Mouse   180 PLSYAPVYGSGLTDQMDFWGRVKN-ILMFFHFTKKRRDIFSQYGNTVQEHFAEGSQPVLSD---- 239

  Fly   248 KHMERQISVMLLNSHAPLTTARPTVDAMVPVGGMHIYPPKPLPADMQALLDG-ATEGAIFFSLG- 310
              :..:..:..:||...|..|||.....|.|||:...|.:|:|.|::..:.. ...|.:..:||
Mouse   240 --LLLKAELWFVNSDFALDFARPLFPNTVYVGGLLDKPVQPIPQDLEDFISQFGDSGFVLVALGS 302

  Fly   311 --SNVQSKDMPVEMLRLFLQVFGSLKQRVLWKFED----ESISQLPDNVMVRKWLPQADILAHRH 369
              |.:|||::..||    ...|..|.|.|||..:.    :.:|..| ||.:..||||.|:|||..
Mouse   303 VVSMIQSKEIIKEM----NSAFAHLPQGVLWTCKSSHWPKDVSLAP-NVKIMDWLPQIDLLAHPS 362

  Fly   370 VKVFITHGGLFGTQEGVHYAVPMLGIPFYCDQHLNMNKAVLGGYAISLHFQSITEEILRHSLDQL 434
            :::|:||||:....|.||:.|||:||||:.||..||.:.......:|:..|::..|....::.::
Mouse   363 IRLFVTHGGMNSVMEAVHHGVPMVGIPFFGDQPENMVRVEAKNLGVSIQLQTLKAESFLLTMKEV 427

  Fly   435 IHNVTYKENVQRVSDIFRDRPLEPRKSAVYWIEYVIRHRGASHMRSAGLDLNWFQFYLLDVIAFV 499
            |.:..||........|.:..||.|.:..|.||:::::..||:|::.......|.:.|:|||..|:
Mouse   428 IEDQRYKTAAMASKVIRQSHPLTPAQRLVGWIDHILQTGGAAHLKPYAFQQPWHEQYMLDVFLFL 492

  Fly   500 AIIALAGVMALSLAIRLLMGSNKK---HRKAKQ 529
            ..:.|.   .|.|::::|:...:.   .||.||
Mouse   493 LGLTLG---TLWLSVKVLVAVTRYLSISRKVKQ 522

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt49C1	NP_001036565.1	egt	22..504	CDD:223071	143/511 (28%)
		UDPGT	37..498	CDD:278624	138/490 (28%)
Ugt3a1	NP_997099.2	UDPGT	24..488	CDD:278624	139/498 (28%)
		egt	<235..488	CDD:223071	82/263 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167840796
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.740