Protein Alignment Ugt49C1 and ugt2a3

DIOPT Version :10

• Sequence 1: NP_611564.2
• Gene: Ugt49C1 / 37421
• FlyBaseID: FBgn0034605
• Length: 530
• Species: Drosophila melanogaster
• Sequence 2: NP_001170814.2
• Gene: ugt2a3 / 100384900
• ZFINID: ZDB-GENE-080721-22
• Length: 532
• Species: Danio rerio
• Alignment Length: 553
• Identity: 157/553 - (28%)
• Similarity: 258/553 - (46%)
• Gaps: 57/553 - (10%)

  Fly     8 GLLLTGTLYSQLELAEGSKILAVYAFPGK-SHFMMHTALIRELVESGHQVTMVTAFSLEKEQLGS 71
            |.||...|...:::....::|.:   ||: ||:....|:|..||:..|.||::         :||
Zfish     4 GALLVCLLLCGVDVGWSGRVLVM---PGEYSHWHNMRAIIEALVDRNHSVTVL---------VGS 56

  Fly    72 NYTEILIEPVYDFWHDVKLNFGAQHLFELTRMTNYDFLKMLEIIGLKTTEHALRQPKVRSLIHA- 135
            :...:   |     |..|..|. .|:|::............:.|.|...|.|.:...|.::...
Zfish    57 SSPTV---P-----HTQKARFD-YHVFKVNIEKEEADAVWSDFIYLWMNETATKYETVSNIFQVM 112

  Fly   136 --------EQKEGVF--DLL--LAEQFYQEAFL--------ALAHLYKIPVVTTSTLGYENHMSQ 180
                    |..:|:|  |||  |.|..|...|.        .:|....||:|.:....:.....:
Zfish   113 SRFMTLTDEVCKGMFKEDLLQMLRESHYDVLFSDPMMPCSDLMAQTLNIPLVLSLRATFAYSFER 177

  Fly   181 MMG-LITPWSFVPHGFM--PFTDRMSFLERVKNSYASFYEDMDRLLNYFPKMDAVAREFFGPVLT 242
            |.| :..|.|:||...:  ..||||||:|||:|....|..|:...|......|.:..|..|...|
Zfish   178 MCGQMPAPPSYVPAASLRDHLTDRMSFMERVENMLLYFSHDVFFKLYMMFTFDRIYTEIRGKPTT 242

  Fly   243 EVPKVKHMERQISVMLLNSHAPLTTARPTVDAMVPVGGMHIYPPKPLPADMQALLDGATE-GAIF 306
            ....:    .:..:.|:.::......||.......|||:|..|.|||..:|:..:..:.: |.:.
Zfish   243 MCETM----GKADIWLIRTYWDFEYPRPFPPNFKFVGGLHCKPAKPLSKEMEEFVQSSGDHGVVV 303

  Fly   307 FSLGSNVQSKDMPVEMLRLFLQVFGSLKQRVLWKFEDESISQLPDNVMVRKWLPQADILAHRHVK 371
            |||||.:  |::..|.........|.:.|:|:|::..::...|..|..:..|:||.|:|.|...|
Zfish   304 FSLGSMI--KNLTSERANTIAAALGQIPQKVVWRYSGKTPETLAPNTKIYDWIPQNDLLGHPKTK 366

  Fly   372 VFITHGGLFGTQEGVHYAVPMLGIPFYCDQHLNMNKAVLGGYAISLHFQSITEEILRHSLDQLIH 436
            .||||||..|..|.:::.|||:|:|.:.||..|:......|.|:.|...::..:.|..:|..:::
Zfish   367 AFITHGGTNGLYEAIYHGVPMVGLPLFADQPDNLLHMKTKGAAVVLDINTLESKDLVDALKTVLN 431

  Fly   437 NVTYKENVQRVSDIFRDRPLEPRKSAVYWIEYVIRHRGASHMRSAGLDLNWFQFYLLDVIAFV-- 499
            |.:|||::.|:|.|..|:|::|...||||||:|:|::||.|:|....:|:|:|::.|||.||:
Zfish   432 NPSYKESIMRLSRIHHDQPMKPLDQAVYWIEFVMRNKGAKHLRVQAHELSWYQYHCLDVAAFLLS 496

  Fly   500 --AIIALAGVMALSLAIRLLMGSNKKHRKAKQN 530
              |:|....|.|.....|..:...:..||.:::
Zfish   497 IAALITFLWVKACCFLFRRCVRKTRPERKTQKS 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt49C1	NP_611564.2	Glycosyltransferase_GTB-type	37..498	CDD:471961	141/485 (29%)
ugt2a3	NP_001170814.2	UDPGT	21..519	CDD:278624	151/524 (29%)