Protein Alignment Ugt49B1 and Ugt1a6a

DIOPT Version :10

• Sequence 1: NP_611563.1
• Gene: Ugt49B1 / 37420
• FlyBaseID: FBgn0027073
• Length: 532
• Species: Drosophila melanogaster
• Sequence 2: NP_659545.2
• Gene: Ugt1a6a / 94284
• MGIID: 2137698
• Length: 531
• Species: Mus musculus
• Alignment Length: 563
• Identity: 154/563 - (27%)
• Similarity: 256/563 - (45%)
• Gaps: 86/563 - (15%)

  Fly    14 LVALQQLELGTGSRILAAFFFPGK--------SHFMMTNAIIRELVKQGHEVTFITP-------- 62
            |.|.|.|..|....:|.|.....|        ||::....|:..|.::||::..:.|
Mouse     5 LPAAQTLPAGFLFLVLWASVLGDKLLVVPQDGSHWLSMKEIVEHLSERGHDIMVLVPEVNLLLGE 69

  Fly    63 --------FSL--AKEKLGSNYKEI----VIPQYDFWPEIKEMTNKNTVLEM---------TDLP 104
                    ||:  :.|:|.:.::..    .:|.......::|..|...|::|         .|..
Mouse    70 SKYYRRKIFSVTYSLEELQTRFRTFGNNHFLPGASLMGPLREYRNNMIVVDMFFSNCQSLLKDSA 134

  Fly   105 TFAFLRMVNVMGIHTTDFALEQPEIQAVINEKNKIGKYDLLLAEQFFNEGALILGHLYQIPTITI 169
            |.:|||.                            .|:|.|..:.....| :||.....:|::.:
Mouse   135 TLSFLRE----------------------------NKFDALFTDPAMPCG-VILAEYLNLPSVYL 170

  Fly   170 STFGNANHLSQLFG-VVSPWSYVPHAYMPYTDRMTLWERIGNVAMSAAEDLVREFSYYPGQDAVL 233
            .. |....|..:.| ..||.||||..|..::|.||..:|:.|..::..|:    :.||    .:.
Mouse   171 FR-GFPCSLEHMLGQSPSPVSYVPRFYTKFSDHMTFPQRLANFIVNILEN----YLYY----CLY 226

  Fly   234 KKH---FSKLLDRVPTIKELERNISAILLNSYMPLASSRPMAYNMIPVGGLHIQPPKALPEHLQK 295
            .|:   .|.||.|..::..|.:| |..||.........||:..|||.:||::.:....|.:..:.
Mouse   227 SKYEIIASDLLKRDVSLPSLHQN-SLWLLRYDFVFEYPRPVMPNMIFLGGINCKKKGKLTQEFEA 290

  Fly   296 FLDGA-THGAIYFSLGSQVRSADLPPEKLKVFLEVFGSLKQRVLWKFEDESLPNLPANVKVQSWL 359
            :::.: .||.:.|||||.|  :::|.:|.....|..|.:.|.|||::......||..|..:..||
Mouse   291 YVNASGEHGIVVFSLGSMV--SEIPEKKAMEIAEALGRIPQTVLWRYTGTRPSNLAKNTILVKWL 353

  Fly   360 PQGDILAHPNVKVFIAHGGLFGTQEAVYNGVPILGMPVYCDQHQNINQGKSAEYALGLDYRKVTV 424
            ||.|:|.||..:.||.|.|..|..|.:.||||::.||::.||..|..:.::....:.|:..::|.
Mouse   354 PQNDLLGHPKTRAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTA 418

  Fly   425 EELRGLLMELIENPKYRNNIKKASRIFRDRPLGAMDTAIYWINYVIEHRGAPHLVAAGVHLPWYQ 489
            ::|...|..:|.|..|:.||.:.|.:.:|||:..:|.|::|:.||:.|:|||||..|...|.|||
Mouse   419 DDLENALKTVINNKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDLTWYQ 483

  Fly   490 FYLLDIVGLGLAVILLPIVVLILICRRSSKPKSTPTKKKTKKN 532
            ::.||::|..||::|..:.::...|....: |....|.:.||:
Mouse   484 YHSLDVIGFLLAIVLTVVFIVFKCCAYGCR-KCFGGKGRVKKS 525

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt49B1	NP_611563.1	Glycosyltransferase_GTB-type	38..515	CDD:471961	141/512 (28%)
Ugt1a6a	NP_659545.2	UDPGT	27..522	CDD:278624	145/536 (27%)