Protein Alignment Ugt49B1 and ATG26

DIOPT Version :10

• Sequence 1: NP_611563.1
• Gene: Ugt49B1 / 37420
• FlyBaseID: FBgn0027073
• Length: 532
• Species: Drosophila melanogaster
• Sequence 2: NP_013290.1
• Gene: ATG26 / 850886
• SGDID: S000004179
• Length: 1198
• Species: Saccharomyces cerevisiae
• Alignment Length: 477
• Identity: 106/477 - (22%)
• Similarity: 175/477 - (36%)
• Gaps: 135/477 - (28%)

  Fly    45 AIIRELVKQGHEVTFIT--PFSLAKEKLGSNYKEIV---IPQYDFWPE--------IKEMTNK-- 94
            |:.:.|:|:||:|..||  .|....|..|..::||.   :.......|        ::|.::|
Yeast   758 ALGKGLIKEGHQVVIITHSEFRDFVESHGIQFEEIAGNPVELMSLMVENESMNVKMLREASSKFR 822

  Fly    95 -------NTVLEMTDLPTFAFL-----RMVNVMGIHTTDFALEQPEIQA---------------V 132
                   .|..|:.:...|..|     .||   |||.|: ||:.|..:|               :
Yeast   823 GWIDALLQTSWEVCNRRKFDILIESPSAMV---GIHITE-ALQIPYFRAFTMPWTRTRAYPHAFI 883

  Fly   133 INEKNKIGKYDLL---LAEQFFNEGALILGHL--YQIPTITISTFGNAN-HLSQLFGVVSPWSYV 191
            :.::.:.|.|:.|   |.|..|.:|  |.|.:  :::.|:.:   |..| .|.|...|...::..
Yeast   884 VPDQKRGGNYNYLTHVLFENVFWKG--ISGQVNKWRVETLGL---GKTNLFLLQQNNVPFLYNVS 943

  Fly   192 PHAYMPYTDRMTLWERIGNVAMSAAEDLVREFSYYPGQDAVLKKHFSKLLDRVPTIK---ELERN 253
            |..:.|..| .:.|              ||...|:             .||...|.|   ||:..
Yeast   944 PTIFPPSID-FSEW--------------VRVTGYW-------------FLDDKSTFKPPAELQEF 980

  Fly   254 ISAILLNSYMPLASSRPMAYNMIPVGGLHIQPPKALPEHLQKFLDGATHGAIYFSL--GSQVRSA 316
            ||.         |.|:......|..|.:.:...|.:.|.|   ::......:|..|  |...|..
Yeast   981 ISE---------ARSKGKKLVYIGFGSIVVSNAKEMTEAL---VEAVMEADVYCILNKGWSERLG 1033

  Fly   317 DLPPEKLKVFLEVFGSLKQRVLWKFEDESLPNLPANVKVQSWL-PQGDILAHPNVKVFIAHGGLF 380
            |...:|.:|      .|.:.:|      ::.|:|     ..|| ||.|...|        |||..
Yeast  1034 DKAAKKTEV------DLPRNIL------NIGNVP-----HDWLFPQVDAAVH--------HGGSG 1073

  Fly   381 GTQEAVYNGVPILGMPVYCDQHQNINQGKSAEYALGLDYRKVTVEELRGLLMELIENPKYRNN-- 443
            .|..::..|:|.:..|.:.||.  ...|:..:..:|:..:|:..:.|...|.....|...::.
Yeast  1074 TTGASLRAGLPTVIKPFFGDQF--FYAGRVEDIGVGIALKKLNAQTLADALKVATTNKIMKDRAG 1136

  Fly   444 -IKKASRIFRDRPLGAMDTAIY 464
             |||  :|.::..:....:|||
Yeast  1137 LIKK--KISKEDGIKTAISAIY 1156

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt49B1	NP_611563.1	Glycosyltransferase_GTB-type	38..515	CDD:471961	106/477 (22%)
ATG26	NP_013290.1	GRAM	194..>239	CDD:214725
		PH-GRAM1_AGT26	219..335	CDD:275402
		PH-GRAM2_AGT26	581..673	CDD:275403
		GT1_Gtf-like	744..1155	CDD:340817	103/474 (22%)