DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt49B1 and UGT85A1

DIOPT Version :9

Sequence 1:	NP_611563.1	Gene:	Ugt49B1 / 37420	FlyBaseID:	FBgn0027073	Length:	532	Species:	Drosophila melanogaster
Sequence 2:	NP_173656.1	Gene:	UGT85A1 / 838846	AraportID:	AT1G22400	Length:	489	Species:	Arabidopsis thaliana

Alignment Length:	498	Identity:	109/498 - (21%)
Similarity:	184/498 - (36%)	Gaps:	148/498 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 FPGKSHFMMTNAIIRELVKQGHEVTFITPFSLAKEKLGSNYKEIVIPQYDFWPEIKEMTNKNTVL 98
            :|.:.|......:.:.|..:|..|||                            :..:.|.|..|
plant    19 YPAQGHINPMMRVAKLLHARGFYVTF----------------------------VNTVYNHNRFL 55

  Fly    99 E------MTDLPTFAFLRMVNVMGIHTTDFALEQPEIQAVINE--KNKIGKYDLLLAEQFFNEGA 155
            .      :..||:|.|..:.:  |:..||....| :|.|:...  ||.:..:..||  |..|.|.
plant    56 RSRGSNALDGLPSFRFESIAD--GLPETDMDATQ-DITALCESTMKNCLAPFRELL--QRINAGD 115

  Fly   156 LILGHLYQIPTIT-ISTFGNAN---HLSQLFGV--VSPWSYVPHAYMPYTDRMTLWERIGNVAMS 214
                   .:|.:: |.:.|..:   .:::..||  |..|:....|::.|.......|: |...:.
plant   116 -------NVPPVSCIVSDGCMSFTLDVAEELGVPEVLFWTTSGCAFLAYLHFYLFIEK-GLCPLK 172

  Fly   215 AAEDLVREFSYYPGQDAVLKKHFSKLLDRVPTIK--------------------------ELER- 252
            ....|.:|:.    :|.|        :|.:||:|                          |.||
plant   173 DESYLTKEYL----EDTV--------IDFIPTMKNVKLKDIPSFIRTTNPDDVMISFALRETERA 225

  Fly   253 -NISAILLNSYMPL--------ASSRPMAYNMIPVGGLHIQPPKALPE---------HLQK---- 295
             ..|||:||::..|        .|..|..|:   ||.||:...:.:.|         :|.|
plant   226 KRASAIILNTFDDLEHDVVHAMQSILPPVYS---VGPLHLLANREIEEGSEIGMMSSNLWKEEME 287

  Fly   296 ---FLDGAT-HGAIYFSLGSQVRSADLPPEKLKVFLE----VFGSLKQRVLWKFEDESLPNLPAN 352
               :||..| :..||.:.||      :....:|..:|    :.||.|: .||....:.:....|.
plant   288 CLDWLDTKTQNSVIYINFGS------ITVLSVKQLVEFAWGLAGSGKE-FLWVIRPDLVAGEEAM 345

  Fly   353 V------------KVQSWLPQGDILAHPNVKVFIAHGGLFGTQEAVYNGVPILGMPVYCDQHQNI 405
            |            .:.||.||..:|:||.:..|:.|.|.....|::..|||::..|.:.||..|.
plant   346 VPPDFLMETKDRSMLASWCPQEKVLSHPAIGGFLTHCGWNSILESLSCGVPMVCWPFFADQQMNC 410

  Fly   406 NQGKSAEYALGLDY-RKVTVEELRGLLMELIENPKYRNNIKKA 447
             :....|:.:|::. ..|..||:..::.||::..|.:...:||
plant   411 -KFCCDEWDVGIEIGGDVKREEVEAVVRELMDGEKGKKMREKA 452

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt49B1	NP_611563.1	egt	7..513	CDD:223071	109/498 (22%)
Ugt49B1	NP_611563.1	UDPGT	38..515	CDD:278624	108/494 (22%)
UGT85A1	NP_173656.1	Glycosyltransferase_GTB_type	14..453	CDD:299143	109/498 (22%)
UGT85A1	NP_173656.1	MGT	20..454	CDD:273616	109/497 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	76	1.000	Domainoid score	I3136
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	89	1.000	Inparanoid score	I2281
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.050