Protein Alignment Ugt49B1 and ugt2a6

DIOPT Version :10

• Sequence 1: NP_611563.1
• Gene: Ugt49B1 / 37420
• FlyBaseID: FBgn0027073
• Length: 532
• Species: Drosophila melanogaster
• Sequence 2: NP_001138283.1
• Gene: ugt2a6 / 797211
• ZFINID: ZDB-GENE-081104-3
• Length: 529
• Species: Danio rerio
• Alignment Length: 559
• Identity: 159/559 - (28%)
• Similarity: 267/559 - (47%)
• Gaps: 74/559 - (13%)

  Fly    11 LLSLVALQQLELGTGSRILAAFFFPGK-SHFMMTNAIIRELVKQGHEVTFITPFS------LAKE 68
            ||..:.|..:::|...|:|.   .||: ||:.....:|..||.:.|.||.:...|      ..||
Zfish     6 LLVCLLLCGVDVGWSGRVLV---MPGEYSHWHNMRPVIEALVDKNHSVTVLVGSSSPTVPHTQKE 67

  Fly    69 KLGSNY------KEIVIPQYDF-WPEIKEMTNKNTVLEMTDLPTFAFLRMVNVMGIHTTDF--AL 124
            :...:.      ||:|    |: |....|:....|:  .|...|....:::::...|:.:.  .|
Zfish    68 RFEYHVFKVNMEKEVV----DYLWIHFHELWMNETI--STYEKTLEVWQLMSLFRAHSEELVKGL 126

  Fly   125 EQPEIQAVINEKNKIGKYDLLLAE--QFFNEGALILGHLYQIPTITISTFGNANHLSQLFGVVS- 186
            ....:...:.:.|    ||:|.::  ..|::   ::.....||.:.......|:.|.:|.|.:.
Zfish   127 FDVGLLKTLRDSN----YDVLFSDLTMPFSD---LMAQKLNIPHVLSMRISFASALERLCGQMPV 184

  Fly   187 PWSYVPHAYMP--YTDRMTLWERIGNVAM----SAAEDLVREFSYYPGQDAVLKKHFSKLLDRVP 245
            |.||||.|...  .||||:..||:.|:.:    :|...|..:|::    |.:    ::::.....
Zfish   185 PQSYVPAAVAQGHLTDRMSFTERVENMLLYITHTAMFQLTTKFTF----DHI----YAEISGEPT 241

  Fly   246 TIKELERNISAILLNSYMPLASSRPMAYNMIPVGGLHIQPPKALPEHLQKFLDGA-THGAIYFSL 309
            |:.|........|:.:|......||...|...||||..:|.|.|.:.|::|:..: .||.:.|||
Zfish   242 TMCETIGKTDIWLIRTYWDFEYPRPFPPNFKFVGGLQCKPAKPLAKELEEFVQSSGDHGIVVFSL 306

  Fly   310 GSQVRSADLPPEKLKVFLEVFGSLKQRVLWKFEDESLPNLPANVKVQSWLPQGDILAHPNVKVFI 374
            ||.::  :|..:|........|.:.|:|:|::..::...|..|.|:..|:||.|:|.||..|.||
Zfish   307 GSMIK--NLTVQKANTIAAALGQISQKVVWRYSGKTPETLAPNTKIYDWIPQNDLLGHPKTKAFI 369

  Fly   375 AHGGLFGTQEAVYNGVPILGMPVYCDQHQNINQGKSAEYALGLDYRKVTVEELRGLLMELIENPK 439
            .|||..|..||:|:|||::|:|::.||..|:...||...|:.||:..:..::|...|..::.||.
Zfish   370 THGGTNGLYEAIYHGVPMVGLPLFGDQPDNLMHLKSKGAAVVLDFFTLESKDLVDALKTVLNNPS 434

  Fly   440 YRNNIKKASRIFRDRPLGAMDTAIYWINYVIEHRGAPHLVAAGVHLPWYQFYLLDIVGLGLAVIL 504
            |:.:|.:.|||..|:|:..:|.|:|||.:|:.::||.||......|.|||::.||:     |..|
Zfish   435 YKESIMRLSRIHHDQPMKPLDQAVYWIEFVMRNKGAKHLRVQAHELSWYQYHCLDV-----AAFL 494

  Fly   505 LPIVVLILI------------CRRSSKPKSTPTKKKTKK 531
            |.|..||..            |.|.::|     ::|:||
Zfish   495 LSITALITFLWVKACCFLFRRCVRKTRP-----ERKSKK 528

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt49B1	NP_611563.1	Glycosyltransferase_GTB-type	38..515	CDD:471961	145/513 (28%)
ugt2a6	NP_001138283.1	UDPGT	21..519	CDD:278624	150/528 (28%)