Protein Alignment Ugt49B1 and ugt2b6

DIOPT Version :10

• Sequence 1: NP_611563.1
• Gene: Ugt49B1 / 37420
• FlyBaseID: FBgn0027073
• Length: 532
• Species: Drosophila melanogaster
• Sequence 2: NP_001170806.3
• Gene: ugt2b6 / 792506
• ZFINID: ZDB-GENE-100402-4
• Length: 527
• Species: Danio rerio
• Alignment Length: 546
• Identity: 147/546 - (26%)
• Similarity: 262/546 - (47%)
• Gaps: 53/546 - (9%)

  Fly    12 LSLVALQQLELGTGSRILAAFFFPGKSHFMMTNAIIRELVKQGHEVTFITP-------------F 63
            |||::|  |..|....:|.  :|...||::....::..|:.:||:||.:.|             |
Zfish     8 LSLLSL--LSAGECGNVLV--WFTEGSHWINMKIVLETLIDRGHDVTVLVPDASLFMKANASDRF 68

  Fly    64 SLAKEKLGSNYKE--IVIPQYDFWPEIKEMTNKNTVLEMTDLPTFAFLRMVNVMGIHTTDFALEQ 126
            |.....:..:.:|  :.|.::.:: .:.||...| ..:|.. ..:.|...:..|.|...|..|:.
Zfish    69 SYQPFNVSMDEQEMKVFIEEFLYF-SLYEMDQLN-FFQMQS-KVYEFTSKLQDMSISYCDGVLKS 130

  Fly   127 PEIQAVINEKNKIGKYDLLLAEQFFNEGALILGHLYQIPTITISTFGNANHLSQLFG-VVSPWSY 190
            |.:.    :|.:..|:|::.::..:....::...| .:|.:....|..|:...::.| :.:|.||
Zfish   131 PGLL----DKLRKHKFDVVFSDPIYQCSDIVAEEL-NVPLVYTFRFSLAHAAERMCGQIPAPPSY 190

  Fly   191 VPHAYMPYTDRMTLWERIGNVAMSAAEDLVREFSYYPGQDAVLKKHFSKLLDRVPTIKELERNIS 255
            ||.|....||||:..|||.|:....::|....|::     ..:..::::...|..:..|:.....
Zfish   191 VPGAMSKLTDRMSFTERIYNMLFYLSQDAFAVFAW-----KKIDNYYTEYFGRPTSYCEMMGRAD 250

  Fly   256 AILLNSYMPLASSRPMAYNMIPVGGLHIQPPKALPEHLQKFLDGA-THGAIYFSLGSQVRSADLP 319
            ..|:.:|......||...|...:||||..|.|.||:.:::|:..: ..|.:.|:|||.|  ..:|
Zfish   251 IWLIRTYWDFEFPRPFVPNFKYIGGLHCTPAKPLPKDMEEFVQSSGDDGIVVFTLGSLV--GKVP 313

  Fly   320 PEKLKVFLEVFGSLKQRVLWKFEDESLPNLPANVKVQSWLPQGDILAHPNVKVFIAHGGLFGTQE 384
            .|...........:.|:|||::..|....|..|.::..|:||.|:|.||..:.||.|||..|..|
Zfish   314 KEISNRIASALAQIPQKVLWRYGGEKPDTLGENTRIYKWIPQNDLLGHPKTRAFITHGGTNGIYE 378

  Fly   385 AVYNGVPILGMPVYCDQHQNINQGKSAEYALGLD-YRKVTVEELRGLLMELIENPKYRNNIKKAS 448
            |:|:|||::|:|::.||..|:....:...|:.:| .:.:..:||...|..:|.:|.|:.|..:.|
Zfish   379 AIYHGVPMVGIPLFGDQPDNMVHMTTRGAAVVVDSIKSMQPQELVDKLNTVINDPSYKENAMRLS 443

  Fly   449 RIFRDRPLGAMDTAIYWINYVIEHRGAPHLVAAGVHLPWYQFYLLDIVGLGLAVILLPIVV---- 509
            ||..|||:..:|.:::||.:|:.::||.||.....:|.|||::.||:......|:.|.:.:
Zfish   444 RIHHDRPMKPLDESVFWIEFVMRNKGAKHLRVEAHNLTWYQYHCLDVFAFLTTVLTLVLYICFKM 508

  Fly   510 ----LILICRRSSKPKSTPTKKKTKK 531
                ::..|.||        |:|:||
Zfish   509 AKFFIMRCCFRS--------KRKSKK 526

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt49B1	NP_611563.1	Glycosyltransferase_GTB-type	38..515	CDD:471961	132/502 (26%)
ugt2b6	NP_001170806.3	None