Protein Alignment Ugt49B1 and ugt5c2

DIOPT Version :10

• Sequence 1: NP_611563.1
• Gene: Ugt49B1 / 37420
• FlyBaseID: FBgn0027073
• Length: 532
• Species: Drosophila melanogaster
• Sequence 2: NP_001038851.1
• Gene: ugt5c2 / 751669
• ZFINID: ZDB-GENE-060825-206
• Length: 552
• Species: Danio rerio
• Alignment Length: 526
• Identity: 158/526 - (30%)
• Similarity: 250/526 - (47%)
• Gaps: 41/526 - (7%)

  Fly    25 GSRILAAFFFPGK-SHFMMTNAIIRELVKQGHEVTFITPFS--LAKEKLGSNYKEIVIPQYDFWP 86
            |.:||.|   |.: ||::..:.:|:.|..|||.|..|...:  ..||. .:.|..|.||....|.
Zfish    48 GGKILVA---PLEGSHWVNMDILIKALHGQGHTVDVIRNANSWFIKEN-STYYDTITIPNTKGWD 108

  Fly    87 E----------IKEMTNKNTVLEMTD--LPTFAFLRMVNVMGIHTTDFALEQPEIQAVINEKNKI 139
            |          ||....|.:.|.:..  |..|..::..:.|........|:..||..::|||
Zfish   109 EEFAADFVYKMIKYEKEKGSWLSIVRLYLNVFDAVKKTHEMVCQLITNILDSEEILKMLNEK--- 170

  Fly   140 GKYDLLLAEQFFNEGALILGHLYQIP---TITISTFGNANHLSQLFGVV-SPWSYVPHAYMPYTD 200
             :|||:|.:..:..| :||.|..::|   .:..:|.|..:     |.:. ||.||:|......||
Zfish   171 -QYDLMLTDPVWGTG-IILAHKLKLPMVYNVRWTTTGEGH-----FDIAPSPMSYIPITGSGNTD 228

  Fly   201 RMTLWERIGNVAMSAAEDLVREFSYYPGQDAVLKKHFSKLLDRVPTIKELERNISAILLNSYMPL 265
            ||:.::|:.|.......||...........|:..|:|:..::    ..||.:.....|:......
Zfish   229 RMSFFQRLKNYFFYLLLDLQLSHFNVKQYQAICDKYFTSRVN----FHELLQGADLWLMRVDFVF 289

  Fly   266 ASSRPMAYNMIPVGGLHIQPPKALPEHLQKFLDGA-THGAIYFSLGSQVRSADLPPEKLKVFLEV 329
            ...||...|:|.:||....|.|.||..|:.|:..: .||.|..||||.:  .:||..........
Zfish   290 EFPRPTMPNIIYIGGFQCPPAKPLPHDLEDFMQSSGDHGVIVMSLGSLI--GNLPENVTAEIAAA 352

  Fly   330 FGSLKQRVLWKFEDESLPNLPANVKVQSWLPQGDILAHPNVKVFIAHGGLFGTQEAVYNGVPILG 394
            |..|.|:|:|::..:....|..|..:..|:||.|:|.||..||||:|||..|..||:|:|||::|
Zfish   353 FARLPQKVIWRYTGKKPSTLSNNTLMVDWMPQKDLLGHPKTKVFISHGGTNGVLEALYHGVPVIG 417

  Fly   395 MPVYCDQHQNINQGKSAEYALGLDYRKVTVEELRGLLMELIENPKYRNNIKKASRIFRDRPLGAM 459
            :|.:.||:.|:.:.::...|..|....:....|...:.|:|..|.||.|:.|.|.:.:|:|:..:
Zfish   418 IPFFFDQYDNLIRLQARGGAKLLSIADLGENTLHAAIQEVINEPSYRLNMHKLSHLHKDKPVKPL 482

  Fly   460 DTAIYWINYVIEHRGAPHLVAAGVHLPWYQFYLLDIVGLGLAVILLPIVVLILICRRSSKPKSTP 524
            |:||:||.:|:.|:||.||......:|||.::.:|:|....||:|: :...|.:..|....|...
Zfish   483 DSAIFWIEFVMRHKGAAHLRTESYKMPWYSYHSVDVVVTLFAVVLI-LTYCIFVTVRYLCVKCCS 546

  Fly   525 TKKKTK 530
            .|:||:
Zfish   547 QKRKTE 552

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt49B1	NP_611563.1	Glycosyltransferase_GTB-type	38..515	CDD:471961	148/495 (30%)
ugt5c2	NP_001038851.1	UDPGT	49..551	CDD:278624	155/522 (30%)