Protein Alignment Ugt49B1 and Ugt2b1

DIOPT Version :10

• Sequence 1: NP_611563.1
• Gene: Ugt49B1 / 37420
• FlyBaseID: FBgn0027073
• Length: 532
• Species: Drosophila melanogaster
• Sequence 2: NP_690024.1
• Gene: Ugt2b1 / 71773
• MGIID: 1919023
• Length: 529
• Species: Mus musculus
• Alignment Length: 551
• Identity: 162/551 - (29%)
• Similarity: 274/551 - (49%)
• Gaps: 42/551 - (7%)

  Fly     1 MSLKSALHIFLLSLVALQQLELGTGSRILAAFFFPGK-SHFMMTNAIIRELVKQGHEVTFITPFS 64
            ||:|.|....|:..:.  .:..|...::|.   :|.: ||::....|:.|||::||:||.:  .|
Mouse     1 MSMKQASVFLLIQFIC--YIRPGACGKVLV---WPTEYSHWINMKIILDELVQRGHDVTVL--IS 58

  Fly    65 LAKEKLGS------NYKEIVIP------QYDFWPEIKEMTNKNTVLEMTDLPTFAFLRMVNVMGI 117
            .|...:|.      |::....|      :|.|     |....|...|:..||.:.....:..:..
Mouse    59 SASILIGPSNESSINFEIYSAPLSKDDLEYAF-----EKWVGNWTYELKKLPFWTSYSKLQKISS 118

  Fly   118 HTTDFALEQPEIQAVINEKNKI-----GKYDLLLAEQFFNEGALILGHLYQIPTITISTFGNANH 177
            ..:|  :.:...:||:..|:.:     .|:|::||:.....|.| |..|.:.|.:....|.....
Mouse   119 EYSD--MIESFCKAVVWNKSLMKKLQGSKFDVVLADALVPCGEL-LSELLKTPLVYSLRFCPGYK 180

  Fly   178 LSQLF-GVVSPWSYVPHAYMPYTDRMTLWERIGNVAMSAAEDLVREFSYYPGQDAVLKKHFSKLL 241
            ..:.. |:..|.||||......:|.||..||:.|:    .:.|:.:|.:....:....:.:|.:|
Mouse   181 CEKYSGGLPLPPSYVPVVLSELSDHMTFAERVKNM----LQVLLFDFWFQTFNEKSWNQFYSDVL 241

  Fly   242 DRVPTIKELERNISAILLNSYMPLASSRPMAYNMIPVGGLHIQPPKALPEHLQKFLDGA-THGAI 305
            .|..|:.|:.......|:.::..|....|...|...|||||.:|.|.||:.:::|:..: .||.:
Mouse   242 GRPTTLTEMMGKADIWLVRTFWDLKFPHPFLPNFDFVGGLHCKPAKPLPKEMEEFVQSSGEHGVV 306

  Fly   306 YFSLGSQVRSADLPPEKLKVFLEVFGSLKQRVLWKFEDESLPNLPANVKVQSWLPQGDILAHPNV 370
            .|||||.|:  ::..||..|.......:.|:|||:|:.:....|.:|.::..|:||.|:|.||..
Mouse   307 VFSLGSMVK--NIKEEKANVVASALAQIPQKVLWRFDGKKPDTLGSNTRLYKWIPQNDLLGHPKT 369

  Fly   371 KVFIAHGGLFGTQEAVYNGVPILGMPVYCDQHQNINQGKSAEYALGLDYRKVTVEELRGLLMELI 435
            |.||||||..|..||:|:|:||:|:|::.||..|||...:...|:.:|:..::..:|...|..:|
Mouse   370 KAFIAHGGTNGIYEAIYHGIPIVGIPLFGDQPDNINHIVAKGAAVRVDFDTMSTTDLLTALKTVI 434

  Fly   436 ENPKYRNNIKKASRIFRDRPLGAMDTAIYWINYVIEHRGAPHLVAAGVHLPWYQFYLLDIVGLGL 500
            .:|.|:.|..:.|||..|:|:..:|.|::||.||:.::||.||..|...|.|:|::.||::|. |
Mouse   435 NDPSYKENAMRLSRIHHDQPMKPLDRAVFWIEYVMRNKGAKHLRPALHDLTWFQYHSLDVIGF-L 498

  Fly   501 AVILLPIVVLILICRRSSKPKSTPTKKKTKK 531
            .|.::.:|.:|..|......|:....||.|:
Mouse   499 LVCVVAVVFIIAKCCLFCCHKTANMGKKKKE 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt49B1	NP_611563.1	Glycosyltransferase_GTB-type	38..515	CDD:471961	149/495 (30%)
Ugt2b1	NP_690024.1	UDPGT	24..527	CDD:278624	154/522 (30%)