Protein Alignment Ugt49B1 and ugt5b6

DIOPT Version :10

• Sequence 1: NP_611563.1
• Gene: Ugt49B1 / 37420
• FlyBaseID: FBgn0027073
• Length: 532
• Species: Drosophila melanogaster
• Sequence 2: NP_001035435.1
• Gene: ugt5b6 / 678597
• ZFINID: ZDB-GENE-060421-3572
• Length: 531
• Species: Danio rerio
• Alignment Length: 579
• Identity: 155/579 - (26%)
• Similarity: 262/579 - (45%)
• Gaps: 119/579 - (20%)

  Fly     3 LKSALHIFLLSLVALQQLELGTGSRILAAFFFP-GKSHFMMTNAIIRELVKQGHEVTFITPFSLA 66
            |...|.|.|:::..:|      ..::|.   || ..||::....::..|..:||.:|
Zfish    10 LPVTLTILLVTVPVVQ------SGKVLV---FPVDVSHWVNMKILVEALHAKGHNIT-------- 57

  Fly    67 KEKLGSNYKEIVIPQYDFWPEIKEMTNKNTVLEMTD--------LPTF-----AFLRMVNVMG-- 116
                       |:...|.| .|||.:...|.:.:..        |.||     |.||..::.|
Zfish    58 -----------VMRMADSW-YIKEFSPHYTSINLKSAGGFGEDFLETFASRLMAILREGSIWGRL 110

  Fly   117 -----IHTTDFALEQPEIQAVIN--EKNKI------GKYDLLLAE-QFFNEGALILGHLYQIPTI 167
                 :..|.:.:.:.|...::|  |..|:      .|||::|.: ..|  |.:||||..::|.:
Zfish   111 KLEAEVWQTTWKMIETESVMIVNMIEDQKLMQLLKDAKYDVILTDPTIF--GGVILGHYLKLPMV 173

  Fly   168 -----TISTFGNANHLSQLFGVV-SPWSYVPHAYMPYTDRMTLWERIGNVAMSAAEDLVREFSYY 226
                 ||  :..|:     |.:. ||.||||...:..:|||:..||:.||.|....::.......
Zfish   174 YNARWTI--YSEAH-----FAIAPSPLSYVPFPSLELSDRMSFLERVCNVVMYTIIEIGAALVIA 231

  Fly   227 PGQDAVLKKHFSKLLDRVPTIKELERNISAILLNSYMPLASS---------------RPMAYNMI 276
            |..||:.::...      |.             .||:.|...               ||...|::
Zfish   232 PINDALAERFIG------PG-------------TSYLSLVQGADLWLHRVDFVFEYPRPTMPNIV 277

  Fly   277 PVGGLHIQPPKALPEHLQKFLDGA-THGAIYFSLGSQVRSADLPPEKLKVFLEVFGSLKQRVLWK 340
            .:.|...:|.|.||:.|:.|:..: .||.|..|||:.:  ..||.:..:...|.|..|.|:::|:
Zfish   278 YMAGFQCKPSKPLPQDLEDFVQSSGDHGVIIMSLGTLI--GQLPEDVAEAIAEAFAELPQKIIWR 340

  Fly   341 FEDESLPNLPANVKVQSWLPQGDILAHPNVKVFIAHGGLFGTQEAVYNGVPILGMPVYCDQHQNI 405
            ::.:....|..|..|..|:||.|:|.|...:.|:||||..|.|||:|:||||:|..:..||..|:
Zfish   341 YKGKRPSALGNNTLVMDWMPQNDLLGHSKTRAFVAHGGTNGVQEAIYHGVPIIGFGLIFDQPDNL 405

  Fly   406 NQGKSAEYALGLDYRKVTVEELRGLLMELIENPKYRNNIKKASRIFRDRPLGAMDTAIYWINYVI 470
            ::.:....|..:|:..:..|.....:.|::.||.||.|:::.||:.:|.|:..:|.||:||.:|:
Zfish   406 SKMRVRGAAKNVDFATMDKESFLKTVKEVLYNPTYRENMQRLSRLHKDVPVKPLDNAIFWIEFVM 470

  Fly   471 EHRGAPHLVAAGVHLPWYQFYLLDIVGL---GLAVILLPIVVLI-----LICRRSSKPK 521
            .|:||.||......:|||.::.:|::.:   .:::|:|.|..:|     .||.:.:|.|
Zfish   471 RHKGAAHLRTESNKMPWYSYHSVDVILVLISAVSLIILTIFAVIRYFCCRICMKKTKSK 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt49B1	NP_611563.1	Glycosyltransferase_GTB-type	38..515	CDD:471961	144/535 (27%)
ugt5b6	NP_001035435.1	Glycosyltransferase_GTB-type	27..529	CDD:471961	149/554 (27%)