Protein Alignment Ugt49B1 and Ugt2a1

DIOPT Version :10

• Sequence 1: NP_611563.1
• Gene: Ugt49B1 / 37420
• FlyBaseID: FBgn0027073
• Length: 532
• Species: Drosophila melanogaster
• Sequence 2: XP_063129643.1
• Gene: Ugt2a1 / 63867
• RGDID: 69432
• Length: 737
• Species: Rattus norvegicus
• Alignment Length: 524
• Identity: 156/524 - (29%)
• Similarity: 255/524 - (48%)
• Gaps: 56/524 - (10%)

  Fly    38 SHFMMTNAIIRELVKQGHEVTFITPFSLAKEKLGSNYKEIVIPQYDFWP------EIKEMTNKNT 96
            ||::....::.|||::.|.||.:.    |.|.|..|........::..|      :|.||.....
  Rat   241 SHWLNIKILLEELVQRNHSVTVLA----ASETLFINSSPDAFISFEEIPVSYTRSKIDEMIEHMI 301

  Fly    97 VLEMTDLPT--------------FAFLRMVNVMGIHTTDFALEQPEIQAVINEKNKIGKYDLLLA 147
            .|.:...||              ||....:|.   ...|..|:...:.|.:.:    |.:|:|::
  Rat   302 ALWLDHRPTPLTMWAFYKELGKLFAAFYKINK---QICDGVLKNATLMARLQK----GGFDVLIS 359

  Fly   148 EQFFNEGALI---LGHLYQIPTITISTFGNANHLSQLFG-VVSPWSYVPHAYMPYTDRMTLWERI 208
            :.....|.|:   ||    ||.:....|..|..:.:..| :.:|.||||.|....||:||..||:
  Rat   360 DPVTMCGELVALKLG----IPFVYTLRFSPAFTVERHCGKIPTPVSYVPAALSELTDQMTFGERV 420

  Fly   209 GNVAMSAAEDLVREFSYYPGQDAVLKKHFSKLLDRVPTIKELERNISAILLNSYMPLASSRPMAY 273
            .|....:.:|.:  |..|.|:   ...::|::|.|..|:.|........|:.:|......||...
  Rat   421 KNTISYSLQDYI--FKSYWGE---WNSYYSRVLGRPTTLCETMGKAEIWLMRTYWDFEFPRPYLP 480

  Fly   274 NMIPVGGLHIQPPKALPEHLQKFLD-GATHGAIYFSLGSQVRSADLPPEKLKVFLEVFGSLKQRV 337
            |...|||||.:|.|.||:.:::|:. ...||.:.|||||.|:  :|..||..:.......:.|:|
  Rat   481 NFEFVGGLHCKPAKPLPKEMEEFVQTSGEHGVVVFSLGSMVK--NLTEEKANLIASALAQIPQKV 543

  Fly   338 LWKFEDESLPNLPANVKVQSWLPQGDILAHPNVKVFIAHGGLFGTQEAVYNGVPILGMPVYCDQH 402
            ||:::.:....|.:|.::..|:||.|:|.||..:.||.|||..|..||:|:|:|::|:|::.||.
  Rat   544 LWRYKGKIPATLGSNTRLFDWIPQNDLLGHPKTRAFITHGGTNGIYEAIYHGIPMVGVPMFADQP 608

  Fly   403 QNINQGKSAEYALGLDYRKVTVEELRGLLMELIENPKYRNNIKKASRIFRDRPLGAMDTAIYWIN 467
            .||...|:...|:.::...:|..:|...:..:|..|.|:.|..:.|||..|:|:..:|.|::||.
  Rat   609 DNIAHMKAKGAAVEVNMNTMTSADLLSAVRAVINEPFYKENAMRLSRIHHDQPVKPLDRAVFWIE 673

  Fly   468 YVIEHRGAPHLVAAGVHLPWYQFYLLDIVGLGLA----VILLPIVVLILICRRSSKPKSTPTKKK 528
            :|:.|:||.||..|...|.|:|::.||::|..||    .|||.|...:.:.::..|     |.||
  Rat   674 FVMRHKGAKHLRVAAHDLSWFQYHSLDVIGFLLACMASAILLVIKCCLFVFQKIGK-----TGKK 733

  Fly   529 TKKN 532
            .|::
  Rat   734 NKRD 737

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt49B1	NP_611563.1	Glycosyltransferase_GTB-type	38..515	CDD:471961	151/505 (30%)
Ugt2a1	XP_063129643.1	None