Protein Alignment Ugt49B1 and Ugt1a8

DIOPT Version :9

• Sequence 1: NP_611563.1
• Gene: Ugt49B1 / 37420
• FlyBaseID: FBgn0027073
• Length: 532
• Species: Drosophila melanogaster
• Sequence 2: NP_001365304.1
• Gene: Ugt1a8 / 613123
• MGIID: 3576090
• Length: 530
• Species: Mus musculus
• Alignment Length: 511
• Identity: 140/511 - (27%)
• Similarity: 250/511 - (48%)
• Gaps: 38/511 - (7%)

  Fly    38 SHFMMTNAIIRELVKQGHEVTFITP---FSLAKEKLGSNYKEIVIPQYDFWPEIKEMTN-----K 94
            ||:.....|:.:|..:||||..:.|   :.|.|.      :...:..|.....::::::     .
Mouse    36 SHWFSMKMIVEKLSHRGHEVVVVIPEVSWHLGKS------QNFTVKTYSVSYTLEDLSHHFNFFA 94

  Fly    95 NTVLEMTDLPTFAFLRMVNVMGIHTTD--FALEQPEIQAVINEKN-----KIGKYDLLLAEQFFN 152
            :...|..::..|:.|:       |:..  |.:.....:::.|:|.     |...:|.:..:. |:
Mouse    95 HKQWENREVGMFSLLK-------HSGKGFFQVLFSHCRSLFNDKKLVEYLKQRSFDAVFLDP-FD 151

  Fly   153 EGALILGHLYQIPTITISTFGNANHLSQLFGVVSPWSYVPHAYMPYTDRMTLWERIGNVAMSAAE 217
            ...|.:...:.:|::..|.....::|.:.....||.||||.....:.|.||..||:.|......|
Mouse   152 VCGLTIAKYFSLPSVVFSGGIFCHYLDEGAQCPSPPSYVPRILSKFADTMTFKERVWNYFSYMKE 216

  Fly   218 DLVREFSYYPGQDAVLKKHFSKLLDRVPTIKELERNISAILLNSYMPLASSRPMAYNMIPVGGLH 282
               |.|..|..:.|:  :..|::|....|:.:|..::|..:..:...|...||:..||:.:||::
Mouse   217 ---RAFCPYFFKTAI--EIASEVLQTPVTMTDLFSSVSIWMFRTDFVLEFPRPVMPNMVYIGGIN 276

  Fly   283 IQPPKALPEHLQKFLDGA-THGAIYFSLGSQVRSADLPPEKLKVFLEVFGSLKQRVLWKFEDESL 346
            ..|.|.|.:..:.:::.: .||.:.|||||.|  :::|.:|.....|..|.:.|.|||::.....
Mouse   277 CHPGKPLSKEFEAYVNASGEHGIVVFSLGSMV--SEIPEKKAMEIAEALGRIPQTVLWRYTGTRP 339

  Fly   347 PNLPANVKVQSWLPQGDILAHPNVKVFIAHGGLFGTQEAVYNGVPILGMPVYCDQHQNINQGKSA 411
            .||..|..:..||||.|:|.||..:.||.|.|..|..|.:.||||::.||::.||..|..:.::.
Mouse   340 SNLAKNTILVKWLPQNDLLGHPKTRAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETR 404

  Fly   412 EYALGLDYRKVTVEELRGLLMELIENPKYRNNIKKASRIFRDRPLGAMDTAIYWINYVIEHRGAP 476
            ...:.|:..::|.::|...|..:|.|..|:.||.:.|.:.:|||:..:|.|::|:.||:.|:|||
Mouse   405 GAGVTLNVLEMTADDLENALKTVINNKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAP 469

  Fly   477 HLVAAGVHLPWYQFYLLDIVGLGLAVILLPIVVLILICRRSSKPKSTPTKKKTKKN 532
            ||..|...|.|||::.||::|..||::|..:.::...|....: |....|.:.||:
Mouse   470 HLRPAAHDLTWYQYHSLDVIGFLLAIVLTVVFIVFKCCAYGCR-KCFGGKGRVKKS 524

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt49B1	NP_611563.1	egt	7..513	CDD:223071	135/490 (28%)
		UDPGT	38..515	CDD:278624	135/492 (27%)
Ugt1a8	NP_001365304.1	UDPGT	26..521	CDD:278624	138/506 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167840771
Domainoid	1	1.000	259	1.000	Domainoid score	I1975
eggNOG	1	0.900	-	-		E33208_3BDT1
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	272	1.000	Inparanoid score	I2975
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		otm42461
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	11	10.690