Protein Alignment Ugt49B1 and ugt2a2

DIOPT Version :10

• Sequence 1: NP_611563.1
• Gene: Ugt49B1 / 37420
• FlyBaseID: FBgn0027073
• Length: 532
• Species: Drosophila melanogaster
• Sequence 2: NP_001018306.2
• Gene: ugt2a2 / 553952
• ZFINID: ZDB-GENE-080721-21
• Length: 534
• Species: Danio rerio
• Alignment Length: 533
• Identity: 153/533 - (28%)
• Similarity: 251/533 - (47%)
• Gaps: 64/533 - (12%)

  Fly    35 PGK-SHFMMTNAIIRELVKQGHEVT----------------------FITPFSLAKEKLGSNYKE 76
            ||: ||:.....::.||:.:.|.||                      |..|.| |:|..|::.:.
Zfish    29 PGEYSHWQNMRNVVDELLNRNHTVTVLVCSASPTINFTQQERFQYLVFEVPLS-AQELDGASEEL 92

  Fly    77 IVIPQYDFWPEIKEMTNKNTVLEMTDLPTFAFLRMVNVMGIHTTDFALEQPEIQAVINEKNKIGK 141
            |.|     |.:........|.|::.:|     |..|.||.....|..|..   .|:|.:.:.: |
Zfish    93 IHI-----WTQHPSPNRLQTALQIIEL-----LGRVRVMHRAMCDSMLRN---DALIAQLSAL-K 143

  Fly   142 YDLLLAEQFFNEGALILGHLYQIPTITISTFGNANHLSQLFG-VVSPWSYVPHAYMPYTDRMTLW 205
            :|:|..:..| ..|.:|..:..:|.:..........|.::.| :.:|.|:||......||||...
Zfish   144 FDVLFNDPMF-MCADLLAEMLGLPLVLSVRISPGFCLERMCGQMPAPPSFVPITQTVLTDRMCFM 207

  Fly   206 ERIGNVAMSAAEDLVREFSYYPGQDAVLKKHFSKLLDRVPTIKELERNISAILLNSYMPLASSRP 270
            ||:.|:    ..::|...|:|......|..:::.:|.:..|:.|........|:.:|......||
Zfish   208 ERVQNM----IANIVFSVSFYIVAWISLDSYYTDVLGKPTTMCETMGKADIWLIRTYWDFEYPRP 268

  Fly   271 MAYNMIPVGGLHIQPPKALPEHLQKFLDGA-THGAIYFSLGSQVRSADLPPEKLKVFLEVFGSLK 334
            ...|...|||||.:|.|.|.:.:::|:..: .||.:.|||||.::  :|..|:........|.:.
Zfish   269 FPPNFKFVGGLHCKPAKPLSKEMEEFVQSSGDHGVVVFSLGSMIK--NLTSERANTIAAALGQIP 331

  Fly   335 QRVLWKFEDESLPNLPANVKVQSWLPQGDILAHPNVKVFIAHGGLFGTQEAVYNGVPILGMPVYC 399
            |:|:|::..::...|..|.|:..|:||.|:|.||..|.||.|||..|..||:|:|||::|:|::.
Zfish   332 QKVVWRYSGKTPETLAPNTKIYDWIPQNDLLGHPKTKAFITHGGTNGLYEAIYHGVPMVGLPLFA 396

  Fly   400 DQHQNINQGKSAEYALGLDYRKVTVEELRGLLMELIENPKYRNNIKKASRIFRDRPLGAMDTAIY 464
            ||..|:...|:...|:.||...:..::|...|..::.||.|:.:|.:.|||..|:|:..:|.|:|
Zfish   397 DQPDNLLHMKTKGAAVVLDINTLESKDLVDALKTVLNNPSYKESIMRLSRIHHDQPMKPLDQAVY 461

  Fly   465 WINYVIEHRGAPHLVAAGVHLPWYQFYLLDIVGLGLAVILLPIVVLILI------------CRRS 517
            ||.:|:.::||.||......|.|||::.||:     |..||.|..||..            |.|.
Zfish   462 WIEFVMRNKGAKHLRVQAHELSWYQYHCLDV-----AAFLLSIAALITFLWVKACCFLFRRCVRK 521

  Fly   518 SKPKSTPTKKKTK 530
            ::|:....|.|.:
Zfish   522 TRPERKTQKSKNE 534

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt49B1	NP_611563.1	Glycosyltransferase_GTB-type	38..515	CDD:471961	146/512 (29%)
ugt2a2	NP_001018306.2	UDPGT	23..521	CDD:278624	149/518 (29%)