Protein Alignment Ugt49B1 and Ugt2a2

DIOPT Version :10

• Sequence 1: NP_611563.1
• Gene: Ugt49B1 / 37420
• FlyBaseID: FBgn0027073
• Length: 532
• Species: Drosophila melanogaster
• Sequence 2: NP_001019319.1
• Gene: Ugt2a2 / 552899
• MGIID: 3576095
• Length: 528
• Species: Mus musculus
• Alignment Length: 519
• Identity: 158/519 - (30%)
• Similarity: 265/519 - (51%)
• Gaps: 46/519 - (8%)

  Fly    38 SHFMMTNAIIRELVKQGHEVTFITP----FSLAKEKLGSNYKEIVIPQYDFWPEIKEMTNKNTVL 98
            ||::....::.|||::.|.||.:.|    |..::.....|::||.:....  .:|.|:......|
Mouse    32 SHWLNIKILLEELVQRNHSVTVLAPSETLFINSRLDAFINFEEIPVSYTK--SKIDEIIEHMIAL 94

  Fly    99 EMTDLPT----FAFLR-MVNVMG-IHTT-----DFALEQPEIQAVINEKNKIGKYDLLLAEQFFN 152
            .:...||    :.|.: :.|::. .:||     |..|..|.:.    |:.:.|.:|:|||:....
Mouse    95 WLDHRPTPLTMWTFYKELGNLLATFYTTNKQMCDGVLNNPTVM----ERLQKGGFDVLLADPVTM 155

  Fly   153 EGALI---LGHLYQIPTITISTFGNANHLSQLFG-VVSPWSYVPHAYMPYTDRMTLWERIGNVAM 213
            .|.|:   ||    ||.:....|..|..:.:..| :.:|.||||.|....||:|:..||:.|:..
Mouse   156 CGELVALKLG----IPFVYTLRFSPAFTVERHCGKIPAPISYVPAALSELTDQMSFGERVKNIIS 216

  Fly   214 SAAEDLVREFSYYPGQDAVLKKHFSKLLDRVPTIKELERNISAILLNSYMPLASSRPMAYNMIPV 278
            .:.:|.:  |..|.|:   ...::||:|.|..|:.|........|:.:|......||...|...|
Mouse   217 YSLQDYI--FKTYWGE---WNSYYSKVLGRPTTLCETMGKAEIWLMRTYWDFEFPRPYLPNFEFV 276

  Fly   279 GGLHIQPPKALPEHLQKFLD-GATHGAIYFSLGSQVRSADLPPEKLKVFLEVFGSLKQRVLWKFE 342
            ||||.:|.|.||:.:::|:. ...||.:.|||||.|:  :|..||..:.......:.|:|||:::
Mouse   277 GGLHCKPAKPLPKEMEEFVQTSGEHGIVVFSLGSMVK--NLTDEKANLIASALAQIPQKVLWRYK 339

  Fly   343 DESLPNLPANVKVQSWLPQGDILAHPNVKVFIAHGGLFGTQEAVYNGVPILGMPVYCDQHQNINQ 407
            .:....|.:|.::..|:||.|:|.||..:.||.|||..|..||:|:|:|::|:|::.||..||..
Mouse   340 GKIPDTLGSNTRLFDWIPQNDLLGHPKTRAFITHGGTNGIYEAIYHGIPMVGVPMFADQPDNIAH 404

  Fly   408 GKSAEYALGLDYRKVTVEELRGLLMELIENPKYRNNIKKASRIFRDRPLGAMDTAIYWINYVIEH 472
            .|:...|:.::...:|..:|...|..:|..|.|:.|..:.|||..|:|:..:|.|::||.:|:.|
Mouse   405 MKAKGAAVEVNMNTMTSSDLLNALRTVINEPSYKENAMRLSRIHHDQPVKPLDRAVFWIEFVMRH 469

  Fly   473 RGAPHLVAAGVHLPWYQFYLLDIVGLGLAVILLPIVVLILIC----RRSSKPKSTPTKKKTKKN 532
            :||.||..|...|.|:|::.||::|..||.:...|:::...|    ::..|     |.||.|::
Mouse   470 KGAKHLRVAAHDLSWFQYHSLDVIGFLLACVASAILLVAKCCLFIFQKVGK-----TGKKKKRD 528

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt49B1	NP_611563.1	Glycosyltransferase_GTB-type	38..515	CDD:471961	153/500 (31%)
Ugt2a2	NP_001019319.1	UDPGT	22..516	CDD:278624	153/500 (31%)