Protein Alignment Ugt49B1 and Ugt1a7c

DIOPT Version :10

• Sequence 1: NP_611563.1
• Gene: Ugt49B1 / 37420
• FlyBaseID: FBgn0027073
• Length: 532
• Species: Drosophila melanogaster
• Sequence 2: NP_964004.1
• Gene: Ugt1a7c / 394432
• MGIID: 3032636
• Length: 531
• Species: Mus musculus
• Alignment Length: 526
• Identity: 145/526 - (27%)
• Similarity: 244/526 - (46%)
• Gaps: 67/526 - (12%)

  Fly    38 SHFMMTNAIIRELVKQGHEVTFITP------------------FSLAKEKLGSNYKEIVIPQYDF 84
            ||:.....::.:|:.:||||..:.|                  .|..:|.|...:|..:..|
Mouse    36 SHWFTMQTVVEKLLHKGHEVVVVVPEVSWQLTKPLNFVVKTYAVSHTQEDLNREFKIFIDAQ--- 97

  Fly    85 WPEIKEMTNKNTVLEMTDLPTFAFLRMVNVMGIHTTDFALEQPEIQAVINEKN-----KIGKYDL 144
            |...:|    ..:|.:.|.|...|             |.|.....:::.|:|.     |...:|.
Mouse    98 WKSQQE----GGILPLLDSPAKGF-------------FELLFSHCRSLFNDKKLVEYLKQTSFDA 145

  Fly   145 LLAEQFFNEGALILGHLYQIPTITISTFGNANHLSQLFGVVSPWSYVPHAYMPYTDRMTLWERIG 209
            :..:. |:...|.:...:.:|::..|.....::|.......||.||:|...:.:||.||..||..
Mouse   146 VFLDP-FDVCGLTVAKYFSLPSVVFSRGIFCHYLEDAAQCPSPPSYIPRMLLKFTDTMTFKERTR 209

  Fly   210 NVAMSAAEDLVREFSYYPGQDAVLKKHF-------SKLLDRVPTIKELERNISAILLNSYMPLAS 267
            |:..            |.|:.|...|.|       |::|....|:.:|...:|..||.:...|..
Mouse   210 NLLA------------YMGERAFCHKFFKSAADIASEVLQTPVTMTDLFSPVSIWLLRTDFVLEF 262

  Fly   268 SRPMAYNMIPVGGLHIQPPKALPEHLQKFLDGA-THGAIYFSLGSQVRSADLPPEKLKVFLEVFG 331
            .||:..|:|.:||::....|.|.:..:.:::.: .||.:.|||||.|  :::|.:|.....|..|
Mouse   263 PRPVMPNVIYIGGINCHQGKPLSKEFEAYVNASGEHGIVVFSLGSMV--SEIPEKKAMEIAEALG 325

  Fly   332 SLKQRVLWKFEDESLPNLPANVKVQSWLPQGDILAHPNVKVFIAHGGLFGTQEAVYNGVPILGMP 396
            .:.|.|||::......||..|..:..||||.|:|.||..:.||.|.|..|..|.:.||||::.||
Mouse   326 RIPQTVLWRYTGTRPSNLAKNTILVKWLPQNDLLGHPKTRAFITHSGSHGIYEGICNGVPMVMMP 390

  Fly   397 VYCDQHQNINQGKSAEYALGLDYRKVTVEELRGLLMELIENPKYRNNIKKASRIFRDRPLGAMDT 461
            ::.||..|..:.::....:.|:..::|.::|...|..:|.|..|:.||.:.|.:.:|||:..:|.
Mouse   391 LFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVINNKSYKENIMRLSSLHKDRPIEPLDL 455

  Fly   462 AIYWINYVIEHRGAPHLVAAGVHLPWYQFYLLDIVGLGLAVILLPIVVLILICRRSSKPKSTPTK 526
            |::|:.||:.|:|||||..|...|.|||::.||::|..||::|..:.::...|....: |....|
Mouse   456 AVFWVEYVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAIVLTVVFIVFKCCAYGCR-KCFGGK 519

  Fly   527 KKTKKN 532
            .:.||:
Mouse   520 GRVKKS 525

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt49B1	NP_611563.1	Glycosyltransferase_GTB-type	38..515	CDD:471961	140/507 (28%)
Ugt1a7c	NP_964004.1	UDPGT	26..522	CDD:278624	143/521 (27%)