Protein Alignment Ugt49B1 and ugt-35

DIOPT Version :10

• Sequence 1: NP_611563.1
• Gene: Ugt49B1 / 37420
• FlyBaseID: FBgn0027073
• Length: 532
• Species: Drosophila melanogaster
• Sequence 2: NP_001023694.1
• Gene: ugt-35 / 3565443
• WormBaseID: WBGene00044286
• Length: 536
• Species: Caenorhabditis elegans
• Alignment Length: 573
• Identity: 129/573 - (22%)
• Similarity: 234/573 - (40%)
• Gaps: 85/573 - (14%)

  Fly     1 MSLKSALHIFLLSLVALQQLELGTGSRILAAFFFPGKSHFMMTNAIIRELVKQGHEVTFITPFSL 65
            |:.:..:..||:|:  |.|........:....|  ..||......|...|.::||.|||:.|..:
 Worm     1 MTCRKTILFFLISI--LFQNSKSVNFLVYCPLF--AHSHHTFLAKIADTLSEEGHNVTFLAPIIV 61

  Fly    66 AKEKLGSNYK------EIVIPQYDFWPEIKEM-------------TNKNTVLEMTDLPTF-AFLR 110
            .|.:   |:|      :|:..|.|  .|:|::             |.:.:|..|  :|:. .|.:
 Worm    62 QKYE---NFKYLKHTTDIIYIQPD--EELKKLGEIMGSAGFSKYWTEEPSVFSM--IPSIKLFQK 119

  Fly   111 MVNVMGIHTTDFALEQPEIQAVINEKNKIGKYDLLLAEQF-FNEGAL--ILGHLYQIPTITISTF 172
            |.:.:        .|.......|.:..|..|:|.::.|.. ||..|:  .||.....||.:: |.
 Worm   120 MFHKI--------YENLRADLSILDSLKDRKFDAMIYEVLAFNAIAIQQYLGIKTLYPTFSV-TH 175

  Fly   173 GNANHLSQLFGVVSPWSYVPHAYMPYTDRMTLWERIGN--------VAMSAAEDLVREFSYYPGQ 229
            |..  ||:..|..:..:.:..|..||.::|...||:.|        |.|...:.:.....||.
 Worm   176 GMV--LSKSIGEPASPATLSSALSPYGEKMNFQERLMNTVCAFIYQVFMKPPKMISYSHPYYE-- 236

  Fly   230 DAVLKKHFSKLLDRVPTIKELERNISAILLNSYMPLASSRPMAYNMIPVGGLHIQPPKALPEHLQ 294
                       :|    :||.|...|.:.|||...|...|||....:.:||:.:...:...|.|.
 Worm   237 -----------ID----LKEAESKASFVFLNSNPYLDFPRPMLTKTVLIGGISVNTSQIREERLS 286

  Fly   295 KFLDGATH---GAIYFSLGSQVRSADLPPEKLKVFLEVFGSLKQ-RVLWKFEDESL--PNLPANV 353
            .......:   ..:..|.||.:.|.|:|.....:.::|...... ..:||:|.:.|  .|...|:
 Worm   287 DEYHNILNIRVKTVLISFGSIMLSTDMPDRYKSIIVKVIEEFPNVTFIWKYESDELDFANNLKNL 351

  Fly   354 KVQSWLPQGDILAHPNVKVFIAHGGLFGTQEAVYNGVPILGMPVYCDQHQNINQGKSAEYALGLD 418
            ....|:||..:||...:..||.|.||....|..|.|.|.:.:|::.||.:|.........::.|:
 Worm   352 HFFKWIPQTALLADSRLSAFITHAGLGSINELSYMGKPAILVPIFADQLRNAKMLVRHNGSISLE 416

  Fly   419 YRKV-TVEELRGLLMELIENPKYRNNIKKASRIFRDRPLGAMDTAIYWINYVIEHRGAPHLVAAG 482
            .:.: ..|:||..|.:::::..::.|.:..:|...::|:...:..|....:..|....|.|....
 Worm   417 KQDLGNFEKLRVSLAKILKDNSFQENAEILARQLNNQPISPRELLIKHATFGAEFGELPSLDPYS 481

  Fly   483 VHLPWYQFYLLDI---VGLGLAVILLPI-----VVLILICRRSSKPKSTPTKK 527
            ..:.::...::||   :|:.||:::..:     ::|.|:.::.:..||...:|
 Worm   482 RQMSFFSLNMIDIFLFLGVFLAILVYFLFTFLRLLLNLLLKKKAVEKSQENRK 534

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt49B1	NP_611563.1	Glycosyltransferase_GTB-type	38..515	CDD:471961	119/522 (23%)
ugt-35	NP_001023694.1	GT1_Gtf-like	23..448	CDD:340817	107/461 (23%)