Protein Alignment Ugt49B1 and Ugt1a8

DIOPT Version :10

• Sequence 1: NP_611563.1
• Gene: Ugt49B1 / 37420
• FlyBaseID: FBgn0027073
• Length: 532
• Species: Drosophila melanogaster
• Sequence 2: NP_787040.2
• Gene: Ugt1a8 / 301595
• RGDID: 708474
• Length: 530
• Species: Rattus norvegicus
• Alignment Length: 525
• Identity: 149/525 - (28%)
• Similarity: 245/525 - (46%)
• Gaps: 66/525 - (12%)

  Fly    38 SHFMMTNAIIRELVKQGHEVTFITPFSLAKEKLGSNYKEIVIPQYDFWPEIKEMTNKNTVLEMTD 102
            ||:.....|:.:|..:||||.                  :|||:.. |       :....|..|
  Rat    36 SHWFTMQMIVEKLSHRGHEVV------------------VVIPEVS-W-------HMGKSLNFT- 73

  Fly   103 LPTFAFLRMVNVMGIHTTDFALEQPEIQAV-----INEKNKIGKYDLL------------LAEQF 150
            :.|::....:..:..|...||..|.:.|.|     :....| |.::||            |.|..
  Rat    74 VKTYSVSYTLEDLNYHFKFFAHNQWKTQEVGMFSLLKHSGK-GFFELLFSHCRSLFKDKKLVEYL 137

  Fly   151 ------------FNEGALILGHLYQIPTITISTFGNANHLSQLFGVVSPWSYVPHAYMPYTDRMT 203
                        |:...|||...:.:|::..|.....::|.:.....||.||||.....:||.||
  Rat   138 KQSSFDAVFLDPFDVCGLILAKYFSLPSVVFSGGIFCHYLDEGAQCPSPPSYVPRILSKFTDTMT 202

  Fly   204 LWERIGNVAMSAAEDLVREFSYYPGQDAVLKKHFSKLLDRVPTIKELERNISAILLNSYMPLASS 268
            ..||:.|......|   |.|..|..:.||  :..|::|....|:::|...:|..:..:...|...
  Rat   203 FKERVWNHLSYMKE---RAFCPYFFKTAV--EIASEVLQTPVTMRDLFSPVSIWMFRTDFVLEFP 262

  Fly   269 RPMAYNMIPVGGLHIQPPKALPEHLQKFLDGA-THGAIYFSLGSQVRSADLPPEKLKVFLEVFGS 332
            ||:..||:.:||::....|.|.:..:.:::.: .||.:.|||||.|  :::|.:|.....|..|.
  Rat   263 RPVMPNMVYIGGINCHQGKPLSKEFEAYVNASGEHGIVVFSLGSMV--SEIPEKKAMEIAEALGR 325

  Fly   333 LKQRVLWKFEDESLPNLPANVKVQSWLPQGDILAHPNVKVFIAHGGLFGTQEAVYNGVPILGMPV 397
            :.|.|||::......||..|..:..||||.|:|.||..:.||.|.|..|..|.:.||||::.||:
  Rat   326 IPQTVLWRYTGTRPSNLAKNTILVKWLPQNDLLGHPKARAFITHSGSHGIYEGICNGVPMVMMPL 390

  Fly   398 YCDQHQNINQGKSAEYALGLDYRKVTVEELRGLLMELIENPKYRNNIKKASRIFRDRPLGAMDTA 462
            :.||..|..:.::....:.|:..::|.::|...|..:|.|..|:.||.:.|.:.:|||:..:|.|
  Rat   391 FGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVINNKSYKENIMRLSSLHKDRPIEPLDLA 455

  Fly   463 IYWINYVIEHRGAPHLVAAGVHLPWYQFYLLDIVGLGLAVILLPIVVLILICRRSSKPKSTPTKK 527
            ::|:.||:.|:|||||..|...|.|||::.||::|..||::|..:.::...|....: |....|.
  Rat   456 VFWVEYVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAIVLTVVFIVYKSCAYGCR-KCFGGKG 519

  Fly   528 KTKKN 532
            :.||:
  Rat   520 RVKKS 524

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt49B1	NP_611563.1	Glycosyltransferase_GTB-type	38..515	CDD:471961	144/506 (28%)
Ugt1a8	NP_787040.2	UDPGT	26..521	CDD:278624	147/520 (28%)