Protein Alignment Ugt49B1 and Ugt2b1

DIOPT Version :10

• Sequence 1: NP_611563.1
• Gene: Ugt49B1 / 37420
• FlyBaseID: FBgn0027073
• Length: 532
• Species: Drosophila melanogaster
• Sequence 2: NP_775417.1
• Gene: Ugt2b1 / 286954
• RGDID: 708541
• Length: 529
• Species: Rattus norvegicus
• Alignment Length: 556
• Identity: 158/556 - (28%)
• Similarity: 270/556 - (48%)
• Gaps: 57/556 - (10%)

  Fly     1 MSLKSALHIFLLSLVALQQLELGTGSRILAAFFFPGK-----------SHFMMTNAIIRELVKQG 54
            ||:|......|:.|:               .:|.||.           ||::....|:.||.::|
  Rat     1 MSMKQTSVFLLIQLI---------------CYFRPGACGKVLVWPTEYSHWINIKIILNELAQRG 50

  Fly    55 HEVT-FITPFSLAKE---KLGSNYKEIVIP------QYDFWPEIKEMTNKNTVLEMTDLPTFAFL 109
            |||| .::..|:..|   :...|::...:|      :|.|...|.|.|..   .|...:.|: :.
  Rat    51 HEVTVLVSSASILIEPTKESSINFEIYSVPLSKSDLEYSFAKWIDEWTRD---FETLSIWTY-YS 111

  Fly   110 RMVNVMGIHTTDFALEQPEIQAVINEKNKIGK-----YDLLLAEQFFNEGALILGHLYQIPTITI 169
            :|..|...::.   :.:...:|:|..|:.:.|     :|::||:.....|.| |..|.:.|.:..
  Rat   112 KMQKVFNEYSD---VVENLCKALIWNKSLMKKLQGSQFDVILADAVGPCGEL-LAELLKTPLVYS 172

  Fly   170 STFGNANHLSQLF-GVVSPWSYVPHAYMPYTDRMTLWERIGNVAMSAAEDLVREFSYYPGQDAVL 233
            ..|.......:.. |:..|.||||......:||||..||:.|:    .:.|..:|.:.|.::...
  Rat   173 LRFCPGYRCEKFSGGLPLPPSYVPVVLSELSDRMTFVERVKNM----LQMLYFDFWFQPFKEKSW 233

  Fly   234 KKHFSKLLDRVPTIKELERNISAILLNSYMPLASSRPMAYNMIPVGGLHIQPPKALPEHLQKFLD 298
            .:.:|.:|.|..|:.|:.......|:.::..|....|...|...|||||.:|.|.||..:::|:.
  Rat   234 SQFYSDVLGRPTTLTEMMGKADIWLIRTFWDLEFPHPFLPNFDFVGGLHCKPAKPLPREMEEFVQ 298

  Fly   299 GA-THGAIYFSLGSQVRSADLPPEKLKVFLEVFGSLKQRVLWKFEDESLPNLPANVKVQSWLPQG 362
            .: .||.:.|||||.|:  :|..||..|.......:.|:|:|:|:.:....|.:|.::..|:||.
  Rat   299 SSGEHGVVVFSLGSMVK--NLTEEKANVVASALAQIPQKVVWRFDGKKPDTLGSNTRLYKWIPQN 361

  Fly   363 DILAHPNVKVFIAHGGLFGTQEAVYNGVPILGMPVYCDQHQNINQGKSAEYALGLDYRKVTVEEL 427
            |:|.||..|.|:||||..|..||:|:|:||:|:|::.||..|||...:...|:.:|:..::...|
  Rat   362 DLLGHPKTKAFVAHGGTNGIYEAIYHGIPIVGIPLFADQPDNINHMVAKGAAVRVDFSILSTTGL 426

  Fly   428 RGLLMELIENPKYRNNIKKASRIFRDRPLGAMDTAIYWINYVIEHRGAPHLVAAGVHLPWYQFYL 492
            ...|..::.:|.|:.|..:.|||..|:|:..:|.|::||.||:.|:||.||.:....|.|:|::.
  Rat   427 LTALKIVMNDPSYKENAMRLSRIHHDQPVKPLDRAVFWIEYVMRHKGAKHLRSTLHDLSWFQYHS 491

  Fly   493 LDIVGLGLAVILLPIVVLILICRRSSKPKSTPTKKK 528
            ||::|..|..::..:.::...|....:..:...|||
  Rat   492 LDVIGFLLLCVVGVVFIITKFCLFCCRKTANMGKKK 527

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt49B1	NP_611563.1	Glycosyltransferase_GTB-type	38..515	CDD:471961	146/493 (30%)
Ugt2b1	NP_775417.1	UDPGT	24..527	CDD:278624	148/516 (29%)