Protein Alignment Ugt49B1 and Ugt2b

DIOPT Version :10

• Sequence 1: NP_611563.1
• Gene: Ugt49B1 / 37420
• FlyBaseID: FBgn0027073
• Length: 532
• Species: Drosophila melanogaster
• Sequence 2: NP_113721.5
• Gene: Ugt2b / 24862
• RGDID: 3936
• Length: 530
• Species: Rattus norvegicus
• Alignment Length: 525
• Identity: 164/525 - (31%)
• Similarity: 257/525 - (48%)
• Gaps: 59/525 - (11%)

  Fly    38 SHFMMTNAIIRELVKQGHEVTFITP---FSLAKEKLGSNYKEIVIPQYDFWPEIKEMTNKNTVLE 99
            ||:|....|:.|||::|||||.:.|   |.|..:|......||      |...|.:...:|..::
  Rat    34 SHWMNIKIILDELVQRGHEVTVLKPSAYFFLDPKKSSDLKFEI------FSTSISKDELQNHFIK 92

  Fly   100 MTDLPTFAFLRMVNVMGIHTTDFALE-QPEIQAVINE--------------------KNKIGKYD 143
            :.|:.|:...|          |..|. .|.:|.::.|                    |.:..|:|
  Rat    93 LLDVWTYELPR----------DTCLSYSPILQNLVYEFSYFYLSICKDAVSNKQLMTKLQESKFD 147

  Fly   144 LLLAEQFFNEGALILGHLYQIPTITISTFGNANHLSQLFG-VVSPWSYVPHAYMPYTDRMTLWER 207
            :|.|:...:.|.|| ..|..||.:...:|...:.|.:..| .:.|.||||........:||..:|
  Rat   148 VLFADPVASCGDLI-AELLHIPFLYSLSFSPGHKLEKSIGKFILPPSYVPVILSGLAGKMTFIDR 211

  Fly   208 IGNVAMSAAEDLVREFSYYPGQDAVLKKHFSKLLDRVPTIKELERNISAILLNSYMPLASSRPMA 272
            :.|:......|...|...:...|.    .:|::|.|..|:.|....:...|:.||..|....|..
  Rat   212 VKNMICMLYFDFWFEILRHKEWDT----FYSEILGRPTTVDETMSKVEIWLIRSYWDLKFPHPTL 272

  Fly   273 YNMIPVGGLHIQPPKALPEHLQKFLDGA-THGAIYFSLGSQVRSADLPPEKLKVFLEVFGSLKQR 336
            .|:..:||||.:|.|.||:.:::|:..: .||.:.|||||.|  :::..||..........:.|:
  Rat   273 PNVDYIGGLHCKPAKPLPKDMEEFVQSSGEHGVVVFSLGSMV--SNMTEEKANAIAWALAQIPQK 335

  Fly   337 VLWKFEDESLPNLPANVKVQSWLPQGDILAHPNVKVFIAHGGLFGTQEAVYNGVPILGMPVYCDQ 401
            |||||:.::...|..|.:|..||||.|||.||..|.|:.|||..|..||:|:|:|::|:|::.||
  Rat   336 VLWKFDGKTPATLGPNTRVYKWLPQNDILGHPKTKAFVTHGGANGLYEAIYHGIPMIGIPLFGDQ 400

  Fly   402 HQNINQGKSAEYALGLDYRKVTVEELRGLLMELIENPKYRNNIKKASRIFRDRPLGAMDTAIYWI 466
            ..||....:...|:.|:.|.::..:....|.|:|:||.|:.|:...|.|..|:|:..:|.|::||
  Rat   401 PDNIAHMVAKGAAVSLNIRTMSKLDFLSALEEVIDNPFYKKNVMLLSTIHHDQPMKPLDRAVFWI 465

  Fly   467 NYVIEHRGAPHLVAAGVHLPWYQFYLLDIVGLGL---AVI-LLPIVVLILICRRSSKPKSTPTKK 527
            .:::.|:||.||...|.:|||||::.||::|..|   ||| .|.:..|:.:.|...|      |:
  Rat   466 EFIMRHKGAKHLRPLGHNLPWYQYHSLDVIGFLLTCFAVIAALTVKCLLFMYRFFVK------KE 524

  Fly   528 KTKKN 532
            |..||
  Rat   525 KKMKN 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt49B1	NP_611563.1	Glycosyltransferase_GTB-type	38..515	CDD:471961	158/506 (31%)
Ugt2b	NP_113721.5	UDPGT	24..527	CDD:278624	162/521 (31%)