Protein Alignment Ugt49B1 and Ugt1a1

DIOPT Version :10

• Sequence 1: NP_611563.1
• Gene: Ugt49B1 / 37420
• FlyBaseID: FBgn0027073
• Length: 532
• Species: Drosophila melanogaster
• Sequence 2: NP_036815.1
• Gene: Ugt1a1 / 24861
• RGDID: 3935
• Length: 535
• Species: Rattus norvegicus
• Alignment Length: 526
• Identity: 151/526 - (28%)
• Similarity: 254/526 - (48%)
• Gaps: 67/526 - (12%)

  Fly    38 SHFMMTNAIIRELVKQGHEVTFITPFSLAKEKLGSNY--KEIVIPQYDFWPEIKEMTNKNTVLEM 100
            ||::....:|::|.::||||..|.|.:....|.||.|  ::..:|          ..|:|.....
  Rat    40 SHWLSMLGVIQQLQQKGHEVVVIAPEASIHIKEGSFYTMRKYPVP----------FQNENVTAAF 94

  Fly   101 TDLPTFAF------LRMVNVMG----------------IHTTDF--ALEQPEIQAVINEKNKIGK 141
            .:|....|      ||:|....                :|..:|  :|||             ..
  Rat    95 VELGRSVFDQDPFLLRVVKTYNKVKRDSSMLLSGCSHLLHNAEFMASLEQ-------------SH 146

  Fly   142 YDLLLAEQFFNEGALILGHLYQIPTITISTFGNANHLS---QLFGVVSPWSYVPHAYMPYTDRMT 203
            :|.||.:.|...|:::..:| .:|.:   .|.||...|   :.....:|.||||.:....||||.
  Rat   147 FDALLTDPFLPCGSIVAQYL-SLPAV---YFLNALPCSLDLEATQCPAPLSYVPKSLSSNTDRMN 207

  Fly   204 LWERIGNVAMSAAEDLVREFSYYP-GQDAVLKKHFSKLLDRVPTIKELERNISAILLNSYMPLAS 267
            ..:|:.|:.::..|:.:....|.| |..|      :::|.:..|:|:|....|..|:.:......
  Rat   208 FLQRVKNMIIALTENFLCRVVYSPYGSLA------TEILQKEVTVKDLLSPASIWLMRNDFVKDY 266

  Fly   268 SRPMAYNMIPVGGLHIQPPKALPEHLQKFLDGA-THGAIYFSLGSQVRSADLPPEKLKVFLEVFG 331
            .||:..||:.:||::....|||.:..:.:::.: .||.:.|||||.|  :::|.:|.....|..|
  Rat   267 PRPIMPNMVFIGGINCLQKKALSQEFEAYVNASGEHGIVVFSLGSMV--SEIPEKKAMEIAEALG 329

  Fly   332 SLKQRVLWKFEDESLPNLPANVKVQSWLPQGDILAHPNVKVFIAHGGLFGTQEAVYNGVPILGMP 396
            .:.|.|||::......||..|..:..||||.|:|.||..:.||.|.|..|..|.:.||||::.||
  Rat   330 RIPQTVLWRYTGTRPSNLAKNTILVKWLPQNDLLGHPKARAFITHSGSHGIYEGICNGVPMVMMP 394

  Fly   397 VYCDQHQNINQGKSAEYALGLDYRKVTVEELRGLLMELIENPKYRNNIKKASRIFRDRPLGAMDT 461
            ::.||..|..:.::....:.|:..::|.::|...|..:|.|..|:.||.:.|.:.:|||:..:|.
  Rat   395 LFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVINNKSYKENIMRLSSLHKDRPIEPLDL 459

  Fly   462 AIYWINYVIEHRGAPHLVAAGVHLPWYQFYLLDIVGLGLAVILLPIVVLILICRRSSKPKSTPTK 526
            |::|:.||:.|:|||||..|...|.|||::.||::|..||::|..:.::...|....: |....|
  Rat   460 AVFWVEYVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAIVLTVVFIVYKSCAYGCR-KCFGGK 523

  Fly   527 KKTKKN 532
            .:.||:
  Rat   524 GRVKKS 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt49B1	NP_611563.1	Glycosyltransferase_GTB-type	38..515	CDD:471961	146/507 (29%)
Ugt1a1	NP_036815.1	UDPGT	30..526	CDD:278624	149/521 (29%)