Protein Alignment Ugt49B1 and Ugt1a2

DIOPT Version :10

• Sequence 1: NP_611563.1
• Gene: Ugt49B1 / 37420
• FlyBaseID: FBgn0027073
• Length: 532
• Species: Drosophila melanogaster
• Sequence 2: NP_038729.1
• Gene: Ugt1a2 / 22236
• MGIID: 3576049
• Length: 533
• Species: Mus musculus
• Alignment Length: 534
• Identity: 150/534 - (28%)
• Similarity: 257/534 - (48%)
• Gaps: 34/534 - (6%)

  Fly    11 LLSLVALQQLELGTGSRILAAFFFPGK-SHFMMTNAIIRELVKQGHEVTFITPFSLAKEKLGSNY 74
            ||.|.||...|   |:::|.   .|.: |.::....::|||..:||: |.:....:.....|.::
Mouse    16 LLLLCALPWAE---GAKVLV---LPMEGSQWLSMRDVVRELHARGHQ-TVVLASEVTVHIKGEDF 73

  Fly    75 KEIVIPQYDFWPEIKEMTNKNTVLEMTDLPTFAFLRMVNVMGIHTTD-----FALEQPEIQAVIN 134
              ..:..|.| |..||...:..:.::.  .||.....|... ..||.     |.|......|:::
Mouse    74 --FTLKTYAF-PYTKEEYQQEILSDIE--KTFKTQHFVKAF-FETTASIRNFFDLYSNSCIALLH 132

  Fly   135 EKNKIGK-----YDLLLAEQFFNEGALILGHLYQIPTITISTFGNANHLSQLFGVVSPWSYVPHA 194
            .|..|.:     :|::|.:..|..||::..:| |||.:.|....:.....:.....:|.||:|:.
Mouse   133 NKMLIQQLNSSFFDVILTDPIFPCGAVLAKYL-QIPAVFILRSLSCGIEYEATQCPNPSSYIPNL 196

  Fly   195 YMPYTDRMTLWERIGNVAMSAAEDLVREFSYYPGQDAVLKKHFSKLLDRVPTIKELERNISAILL 259
            ....:|.|...:|:.|:........:...|..|.:...     |:||.|..::.|:..:.|..|.
Mouse   197 LTRLSDHMDFLQRVQNMLYYLVLKYICRLSITPYESLA-----SELLQREVSLVEVLSHASVWLF 256

  Fly   260 NSYMPLASSRPMAYNMIPVGGLHIQPPKALPEHLQKFLDGA-THGAIYFSLGSQVRSADLPPEKL 323
            .....|...||:..||:.:||::....|.|.:..:.:::.: .||.:.|||||.|  :::|.:|.
Mouse   257 RGDFVLDYPRPIMPNMVFIGGINCVTKKPLSQEFEAYVNASGEHGIVVFSLGSMV--SEIPEKKA 319

  Fly   324 KVFLEVFGSLKQRVLWKFEDESLPNLPANVKVQSWLPQGDILAHPNVKVFIAHGGLFGTQEAVYN 388
            ....|..|.:.|.|||::......||..|..:..||||.|:|.||..:.||.|.|..|..|.:.|
Mouse   320 MEIAEALGRIPQTVLWRYTGTRPSNLAKNTILVKWLPQNDLLGHPKTRAFITHSGSHGIYEGICN 384

  Fly   389 GVPILGMPVYCDQHQNINQGKSAEYALGLDYRKVTVEELRGLLMELIENPKYRNNIKKASRIFRD 453
            |||::.||::.||..|..:.::....:.|:..::|.::|...|..:|.|..|:.||.:.|.:.:|
Mouse   385 GVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVINNKSYKENIMRLSSLHKD 449

  Fly   454 RPLGAMDTAIYWINYVIEHRGAPHLVAAGVHLPWYQFYLLDIVGLGLAVILLPIVVLILICRRSS 518
            ||:..:|.|::|:.||:.|:|||||..|...|.|||::.||::|..||::|..:.::...|....
Mouse   450 RPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAIVLTVVFIVFKCCAYGC 514

  Fly   519 KPKSTPTKKKTKKN 532
            : |....|.:.||:
Mouse   515 R-KCFGGKGRVKKS 527

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt49B1	NP_611563.1	Glycosyltransferase_GTB-type	38..515	CDD:471961	136/487 (28%)
Ugt1a2	NP_038729.1	UDPGT	28..524	CDD:278624	141/514 (27%)