DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt49B1 and ugt-55

DIOPT Version :9

Sequence 1:	NP_611563.1	Gene:	Ugt49B1 / 37420	FlyBaseID:	FBgn0027073	Length:	532	Species:	Drosophila melanogaster
Sequence 2:	NP_506073.2	Gene:	ugt-55 / 188072	WormBaseID:	WBGene00011452	Length:	512	Species:	Caenorhabditis elegans

Alignment Length:	550	Identity:	120/550 - (21%)
Similarity:	217/550 - (39%)	Gaps:	92/550 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 LLSLVALQQLELGTGS-----RILAAFFFPG--KSHFMMTNAIIRELVKQGHEVTFITPF----- 63
            ||:|..|..:.|..|:     |||.  :.|.  .||......|...|.::||.|..:...
Worm     3 LLTLPTLIFIFLNYGTPCLSLRILV--YSPRMIPSHVAFVANIANLLGQRGHNVVVVDNVLRSDI 65

  Fly    64 ----------SLAKEKLGSNYKEIVIPQ---YDFWPEIKEMTNKNTVLEMTDLPTFAFLRMVNVM 115
                      .:.|.:..:|..:::..|   .:||....|...:..|           ::.:.::
Worm    66 SNKLDLKVIEKVVKVETSANVAKLLADQSIPINFWSMRNEPEEQKKV-----------MKQLGII 119

  Fly   116 GIHTTDFALEQPEIQAVINEKNKIGKYDLLLAEQFFNEGALILGHLYQIPTITISTFGNANHLSQ 180
            .:....:.:.:.|  .|.||...: ::|..:.|.|...|..|...|....::.:|:.|..:.:::
Worm   120 FLEQCKYLVSKEE--TVFNELKHL-EFDFGIHEVFDICGIGIFEKLGIRKSVILSSTGMRDIVNE 181

  Fly   181 LFGVVSPWSYVPHAYMPYTDRMTLWERIGNVAMSAAEDLVREFSYYPGQDAVLKKHFSKLLDRVP 245
            ..|:.|          ...|...|.:...::........::..|.:.....|..|....|.:...
Worm   182 ALGISS----------QLQDASILSDYGNSIPFYGIRRNLKFHSAWRNFFEVQSKTLEPLFETTS 236

  Fly   246 TIKELERNISAILLNSYMPLASSRPMAYNMIPVGGLHIQPPKALP-EHLQKFLDGATHGAIYFSL 309
            :.:.|.|..:.:.||::....:.||.:..:..:||:..:.|..|. |::..|  ...:..|..|.
Worm   237 SFENLLRFSNLMFLNTHELADAHRPWSRRVHEIGGISFKFPMPLKNEYINLF--NKYNSIILVSF 299

  Fly   310 GSQVRSADLPPEKLK-VFLEVFGSLKQR-----VLWKFE--DE-SLPNLPANVKVQSWLPQGDIL 365
            |:...|. |.|||.| ..:..|    ||     .:||:|  || :..|...||..:.:|||.|:|
Worm   300 GTTTPSF-LMPEKYKNTLINTF----QRFPDFLFIWKYEKDDEFTQKNKKGNVVFKKFLPQVDLL 359

  Fly   366 AHPNVKVFIAHGGLFGTQEAVYNGVPILGMPVYCDQHQNINQGKSAEYAL--GLDY----RKVTV 424
            ....:|:||.|||.....|..::....|..|::.|||:|      |:.||  ||.:    .::..
Worm   360 ESRKIKLFITHGGQNSLLETFHSNTRTLITPLFGDQHRN------AQIALENGLSHVLLKDQLAN 418

  Fly   425 EEL--RGLLMELIENPKYRNNIKKASRIFRDRPLGAMDTAIYWINYVIEHRGAPHLVAAGVHLPW 487
            |||  ..:......|.|..:|:.|.|...::    |..|:.......:|.....:|  :.::..:
Worm   419 EELVYAAIKQGTESNKKLDDNLLKLSSNLKN----AKQTSENLFLDTVESTYTDNL--SPLNFEF 477

  Fly   488 Y-QFYLLDIVGL---GLAVILLPIVVLILI 513
            | :.|..|.:.|   .:|:..|.::.:|||
Worm   478 YPKLYSSDQILLYLDSIAMFTLTLLTMILI 507

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt49B1	NP_611563.1	egt	7..513	CDD:223071	118/548 (22%)
Ugt49B1	NP_611563.1	UDPGT	38..515	CDD:278624	109/515 (21%)
ugt-55	NP_506073.2	UDPGT	35..>399	CDD:278624	84/400 (21%)
ugt-55	NP_506073.2	Glycosyltransferase_GTB_type	<247..>399	CDD:299143	48/164 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160161624
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.740