DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt49B1 and ugt-30

DIOPT Version :9

Sequence 1:	NP_611563.1	Gene:	Ugt49B1 / 37420	FlyBaseID:	FBgn0027073	Length:	532	Species:	Drosophila melanogaster
Sequence 2:	NP_506729.1	Gene:	ugt-30 / 187955	WormBaseID:	WBGene00011340	Length:	535	Species:	Caenorhabditis elegans

Alignment Length:	518	Identity:	123/518 - (23%)
Similarity:	212/518 - (40%)	Gaps:	76/518 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 SHFMMTNAIIRELVKQGHEVTFITP-FSLAK--EKLGSNY-KEIVIPQ----------------- 81
            ||......:...|.::||.||::.| .::||  |..|... |::||.:
Worm    31 SHSKFLGKLADTLTERGHNVTYLMPVVNIAKRDECKGVKITKDVVIVEAGEKMLSQKQADTPNDE 95

  Fly    82 -YDFWPEIK-EMTNKNTVLEMTDLPTFAFLRMVNVMGIHTTDFALEQPEIQAVINEKNKIGKYDL 144
             .|.|..:: :.:|...:.:.          ..:.|.|...:|...:.     |.|..|...:||
Worm    96 ILDVWWTVQMDSSNSREIFQF----------FCSDMKIACENFLSRRD-----IFEDMKARNFDL 145

  Fly   145 LLAEQFFNEGALILGHLYQI---PTITISTFGNANHLSQLFGVVSP-------WSYVPHAYMPYT 199
            .:.|..   .|..||.:..:   .||..|:       |..:.|:.|       :||||..|....
Worm   146 AILEPV---SACGLGFVKALGIEKTILASS-------SVFYDVILPYIGEPLDYSYVPSGYSVTG 200

  Fly   200 DRMTLWERIGNVAMSAAEDLVREFSYYPGQDAVLKKHFSKLL-DRVPTIKELERNISAILLNSYM 263
            ..::|.|:..|..:|....:..| ..:.|:..:    :.:|| ..:...:.|..:.|...:||..
Worm   201 QELSLGEKFENWMVSREISIALE-GLFDGEMEI----YRRLLGHNLTNWRHLFPSASIFFVNSNP 260

  Fly   264 PLASSRPMAYNMIPVGGLH----IQPPKALPEHLQKFLDGATHGAIYFSLGSQVRSADLPPEKLK 324
            .....||:....:|:||:.    ::....|.|..:|.|:...| .:..|.|:.|.|..:|.:...
Worm   261 FFDFPRPVLEKTVPIGGISVNMGVRKEDMLTEEWEKVLNQRPH-TMLVSFGTLVMSTHMPKKWRS 324

  Fly   325 VFLEVFGSLKQ-RVLWKFE--DESLPNLPANVKVQSWLPQGDILAHPNVKVFIAHGGLFGTQEAV 386
            ..||.|.|... ..:||:|  |.|..|...|:....|:||.::|....:..|::||||....|..
Worm   325 GLLEAFKSFPNVTFIWKYESDDHSFANGIDNIYFSKWVPQNELLNDNRLTAFLSHGGLGSIMELA 389

  Fly   387 YNGVPILGMPVYCDQHQNINQGKSAEYALGLDYRKV-TVEELRGLLMELIENPKYRNNIKKASRI 450
            ::|.|.|.:||:.||.:|.|.......|:.|...:: ..|.|:.....::.:..::||..|.:..
Worm   390 FSGKPALIIPVFADQTRNANTLARHRGAICLHKSQMKNTEVLKKAFKSVLFDASFKNNSLKLAAT 454

  Fly   451 FRDRPLGAMDTAIYWINYVIEHRGAPHLVAAGVHLPWYQFYLLDIVGLGLAVILLPIVVLILI 513
            .|::|....||.|.:..:|.|....|.:...|.||..:|...:||..|   :|::..:.:.||
Worm   455 LRNQPNKPKDTLIKYTEFVGEFGPFPQMDPYGRHLNVFQKSFIDIYTL---IIVVSSIFVALI 514

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt49B1	NP_611563.1	egt	7..513	CDD:223071	121/516 (23%)
Ugt49B1	NP_611563.1	UDPGT	38..515	CDD:278624	123/518 (24%)
ugt-30	NP_506729.1	UDPGT	21..529	CDD:278624	123/518 (24%)
ugt-30	NP_506729.1	Glycosyltransferase_GTB_type	<255..524	CDD:299143	72/264 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160161582
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	172	1.000	Inparanoid score	I2735
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.790