Protein Alignment Ugt49B1 and ugt-8

DIOPT Version :10

• Sequence 1: NP_611563.1
• Gene: Ugt49B1 / 37420
• FlyBaseID: FBgn0027073
• Length: 532
• Species: Drosophila melanogaster
• Sequence 2: NP_504315.1
• Gene: ugt-8 / 186768
• WormBaseID: WBGene00019234
• Length: 531
• Species: Caenorhabditis elegans
• Alignment Length: 563
• Identity: 133/563 - (23%)
• Similarity: 231/563 - (41%)
• Gaps: 76/563 - (13%)

  Fly     1 MSLKSALHIFLLSLVALQQLELGTGSRILAAFFFP--GKSHFMMTNAIIRELVKQGHEVTFITPF 63
            |.:|:.|.|.|:         ||:.|......|.|  |.||....:.:...:...||.||...||
 Worm     1 MHVKNLLSILLV---------LGSVSCKNILIFNPIFGLSHVKFISKMANIIADHGHNVTLFQPF 56

  Fly    64 SLAKEK----LGSNYKEIVIPQYDFWPEIKEMTNKNTVLEMTDLPTFAFLRMVN--VMGIHTTDF 122
            .:|.:.    :.:.|.||:    :::|:..:...|.   |....|.|....::|  |:.......
 Worm    57 HIALKNTEGLIKNKYIEII----NYYPDHYDELLKT---ETATFPAFWDSHLMNNPVLSAFMIPK 114

  Fly   123 AL----EQPEIQAVINEKNKIG-------KYDLLLAEQFFNEGALILGHLYQIPTITISTFGNAN 176
            |:    |:...|.:   |:|:.       .:|::::|.|...| :.:.|:..:|.|.:.:.....
 Worm   115 AIAGEFERTATQLL---KDKVALDDLKSRNFDVIISETFELTG-MYIAHMLNVPCIPVWSAVRFT 175

  Fly   177 HLSQLFGVVSPWSYVPHAYMPYTDRMTLWERIGNVAMSAAEDLVREFSY---YPGQDAVLKKHFS 238
            ..:.:||..|...|....:..........:|:        .|:.|.|.:   ..|..........
 Worm   176 IFNNIFGQPSSLGYSQQPFSKLAPEAGFIDRL--------NDVYRNFFFTITMDGMGQYQNDFIE 232

  Fly   239 KLLDR-VPTIKELERNISAILLNSYMPLASSRPMAYNMIPVGGL--------HIQPPKALPEHLQ 294
            |.:.| :|..|:|.:.......||...|..:.|....::.:||.        |:.|   ||:...
 Worm   233 KAVGRPLPYWKDLIKEAPVYFTNSNEYLDFAVPTTATIVHIGGFTMDLEKMKHVDP---LPDKYA 294

  Fly   295 KFLDGATHGAIYFSLGSQVRSADLPPEKLKVFLEVFGSLKQ-RVLWKFEDESL---PNLPANVKV 355
            |.|: .....:..|.||.:||..:|.......:::|.||.. ..:||:|.:.:   ..||.||.:
 Worm   295 KILE-ERESTVLISFGSVIRSYQMPDNFKAGIIKMFESLPDVTFIWKYERDDVEFQKKLPKNVHL 358

  Fly   356 QSWLPQGDILAHPNVKVFIAHGGLFGTQEAVYNGVPILGMPVYCDQHQNINQGKSAEYALGLDYR 420
            :.|:||..:||...||:|:.||||..|.|..|.|.|.|.:|::.||.:|.|.  .|.:...:.|.
 Worm   359 KKWVPQHSLLADNRVKLFVTHGGLGSTMEVAYTGKPALMVPIFGDQPENANM--LARHGGAISYD 421

  Fly   421 KVTV---EELRGLLMELIENPKYRNNIKKASRIFRDRPLGAMDTAIYWINYVIEHRGAPHLVAAG 482
            |..:   |:|...:.:::.||||..|.::..::...:|:......:..:.:.:|.......|.|.
 Worm   422 KFELADGEKLAITIRDMVRNPKYNKNAQELLKVLSHQPIDPKLNLMKHLEFAMEFPNLRSQVPAI 486

  Fly   483 VHLPWYQFYLLDIV-GLGLAVIL---LPIVVLILICRRSSKPK 521
            ..:.....|.||:: .|.|..||   |...::.|:..|..|.|
 Worm   487 NQMGLIAHYYLDVIFFLSLIFILTVYLTFKIISLLPIRIVKSK 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt49B1	NP_611563.1	Glycosyltransferase_GTB-type	38..515	CDD:471961	119/516 (23%)
ugt-8	NP_504315.1	GT1_Gtf-like	20..457	CDD:340817	109/461 (24%)