Protein Alignment Ugt49B1 and ugt-65

DIOPT Version :10

• Sequence 1: NP_611563.1
• Gene: Ugt49B1 / 37420
• FlyBaseID: FBgn0027073
• Length: 532
• Species: Drosophila melanogaster
• Sequence 2: NP_502373.3
• Gene: ugt-65 / 184205
• WormBaseID: WBGene00008583
• Length: 509
• Species: Caenorhabditis elegans
• Alignment Length: 554
• Identity: 133/554 - (24%)
• Similarity: 223/554 - (40%)
• Gaps: 103/554 - (18%)

  Fly     9 IFLLSLVALQQLELGTGSRILAAFFFPGKSHFMMTNAIIRELVKQGHEVTFITPFSLAKEKLGSN 73
            ||||:    ..|.....||||....|..|||.:....:...|...||:|:..|        :.:|
 Worm    11 IFLLA----HFLTTSNCSRILFLNMFNSKSHALTMMPLAERLFDDGHDVSMYT--------ISAN 63

  Fly    74 YKEIVIPQYDFWPEIKEMTNKNTVLEMTDLPTFAFLRMVNVMGIHTTDFALE------------- 125
                         .:|..:.|..:||..            |.|..|.|.|.:
 Worm    64 -------------RLKIPSKKVKILESL------------VKGSSTDDAAPDTGGVSRIFWSYEM 103

  Fly   126 QPEIQAVINEKNKIG------------------KYDLLLAEQFFN--EGALILGHLYQIPTITIS 170
            .|.:.|...|   ||                  .|||.:.::.:.  :|::.| .|.:..:..|.
 Worm   104 TPYVGAWCYE---IGLYYLEEGRDEQLDEVLATPYDLAVVDETYTSLQGSIAL-KLKEDHSTKII 164

  Fly   171 TFGNANHL---SQLFGVVSPWSYVPHAYMPYTDRMTLWERIGNVAMSAAEDLVREFSY-----YP 227
            ||.....:   |.:.|.......||:.::..::   ::|  || ..:......|.|.|     |.
 Worm   165 TFATTELMPVASNMRGYARNPVTVPNTFLLSSE---VYE--GN-RFAFLTRTRRIFEYFIDQIYS 223

  Fly   228 GQDAVLKKHFS-KLLDRVPTIKELERNISAILLNSYMPLAS-SRPMAYNMIPVGGLHIQPPKALP 290
            |..|.|....| |||......|......|.:.:|.:....| .:|...::|.||. |......||
 Worm   224 GPVASLYSEASGKLLGLTSATKSKTFQNSILTVNDFPDTFSFVQPRGNDLIRVGE-HCYSSANLP 287

  Fly   291 EHLQKFL-DGATHGAIYFSLGSQVRSADLPPEKLKVFLEVFGSLKQ-RVLWKFEDESLPNLPANV 353
            ...:.|: |..:.|.||.::||.:...|.|...::.|:|.....|. ||:|..:. ::.....:|
 Worm   288 SEFRDFVEDSMSKGTIYVAMGSYLNLEDGPKGTVEAFIEALNYFKDYRVIWSHKG-NVTGAKCHV 351

  Fly   354 KVQSWLPQGDILAHPNVKVFIAHGGLFGTQEAVYNGVPILGMPVYCDQHQNINQGKSAEYALGLD 418
            |..:|.||.::|||.....||.||||...:|.|.:|||:|.:|.|.||.:|.::..:...|..|.
 Worm   352 KSVNWAPQKELLAHEKTVAFITHGGLKSAKEGVCSGVPMLFLPFYGDQPRNAHRFVTNGIAEALY 416

  Fly   419 YRKVTVEELRGLLMELIENPKYRNNIKKASRIFRDRPLGAMDTAIYWINYVIEHRGAPH--LVAA 481
            .:.:|..:::..|.:|:.:|.|:||:.|....:.|.|:.::|...:.|:.|:....:.:  ....
 Worm   417 KKAITSLDIQQKLEKLLVDPSYKNNVMKVLSYYLDAPISSLDLGAFHISQVLRRTESQYSKFKRR 481

  Fly   482 GVHLPWYQFYLLDIVGLGLAVILLPIVVLILICR 515
            .:.:...|:..|||       .|:.:|:|.::.:
 Worm   482 SIFMNHLQYLNLDI-------FLVILVILFIVSK 508

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt49B1	NP_611563.1	Glycosyltransferase_GTB-type	38..515	CDD:471961	122/523 (23%)
ugt-65	NP_502373.3	GT1_Gtf-like	25..444	CDD:340817	114/463 (25%)