Protein Alignment Ugt49B1 and ugt-43

DIOPT Version :10

• Sequence 1: NP_611563.1
• Gene: Ugt49B1 / 37420
• FlyBaseID: FBgn0027073
• Length: 532
• Species: Drosophila melanogaster
• Sequence 2: NP_001255487.1
• Gene: ugt-43 / 184052
• WormBaseID: WBGene00008485
• Length: 540
• Species: Caenorhabditis elegans
• Alignment Length: 552
• Identity: 122/552 - (22%)
• Similarity: 220/552 - (39%)
• Gaps: 102/552 - (18%)

  Fly    10 FLLSLVALQQLELGT---GSRILAAFFFPGKSH--FMMTNAIIRELVKQGHEVTFITPFSLAKEK 69
            |||.::|.....:..   |.::|......|.||  ||.|.:.|  |.::|:.||.:.|  |....
 Worm     8 FLLLILASFCFSVSNNIKGKKVLVYLPVTGHSHLKFMSTTSNI--LQEEGYNVTLLLP--LIDIT 68

  Fly    70 LGSNYKEIVIPQYDFWPEIKEMTN-------KNTVLEMTDLPTFAFLRMVNVMG----------- 116
            |.:....||       .:||...|       ..|:::|..:   |..|....||
 Worm    69 LNNTNIPIV-------KKIKHRINLDIHPGVMRTIIKMGGM---ASRRQTWTMGSGIYGFDGISH 123

  Fly   117 ------IHTTDFALEQPEIQAVINEKNKIGKYDLLLAEQFFNEGALILGHLYQIPTITI-STFG- 173
                  .:..|.....|.:.    ::.|..||::.::|.||..|..:..||.....|:: |..|
 Worm   124 LLSDLYSNICDNIFHMPGLL----DRLKAEKYEMGMSEPFFVCGFALFDHLGIDKIISVDSHIGL 184

  Fly   174 NANHLSQLFGVVSPWSYVPHAYMPYTDRMTLWERIGNVAMSAAEDLVREFSYYPGQDAVLKKHFS 238
            ....::..|.|.|  ||:|.|:...:|.|:..||..::                 .:..|.:.|:
 Worm   185 EGPKIAHGFPVTS--SYLPAAFSESSDHMSFVERTRSL-----------------YETYLNRKFA 230

  Fly   239 KLLDR------------VPTIKELERNISAILLNSYMPLASSRPMAYNMIPVGGLHIQPPK---A 288
            :|:..            ..|.:||.|..:.:..||...|....|.....|.:||:.....|   .
 Worm   231 RLIHNKEIDAMKGVYKGKSTWEELMRLPAYMFTNSNPILDFPYPRPSKFIEIGGIAADEKKHDEV 295

  Fly   289 LPEHLQKFLDGATHGAIYFSLGSQVRSADLPPEKLKVFLEVFGSLKQ-RVLWKFEDESL------ 346
            |||.....|: ..:..:..|.||..:|..:|....:..:...|.:.. ..:||:|:.|:
 Worm   296 LPESYDHILN-LRNRTVLISFGSNAKSIFMPDHMRRSLIIALGMMPDITFIWKYENSSIDIVKEF 359

  Fly   347 -PNLPANVKVQSWLPQGDILAHPNVKVFIAHGGLFGTQEAVYNGVPILGMPVYCDQHQNINQGKS 410
             |.:...|:| .|:||..:||.|.:.:|:.|||:..|.|..::|.|.:.:||:.||.:|....:.
 Worm   360 DPTIKNIVQV-DWMPQQALLADPRLDLFVTHGGMASTNEIAFSGKPAVMVPVFGDQTRNSRMLER 423

  Fly   411 AEYAL-----GLDYRKVTVEELRGLLMELIENPKYRNNIKKASRIFRDRPLGAMDTAIYWINYVI 470
            ....|     .|:|.::.:|    .::.::.:|.|....::.:.:.|:.|.......:.:.|:|.
 Worm   424 HGGVLMLRKENLEYPEIVIE----TILSVLNDPSYAERAQQLATLLRNHPESPKQVFLKYFNFVA 484

  Fly   471 EHRGAPHLVAAGVHLPWYQFYLLDIVGLGLAV 502
            .......:.:..:::.:..:|.||::...|.|
 Worm   485 RFGKPTGIDSNSINVDFIAYYYLDLIAFLLIV 516

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt49B1	NP_611563.1	Glycosyltransferase_GTB-type	38..515	CDD:471961	115/521 (22%)
ugt-43	NP_001255487.1	GT1_Gtf-like	28..479	CDD:340817	110/493 (22%)