Protein Alignment Ugt49B1 and ugt-66

DIOPT Version :10

• Sequence 1: NP_611563.1
• Gene: Ugt49B1 / 37420
• FlyBaseID: FBgn0027073
• Length: 532
• Species: Drosophila melanogaster
• Sequence 2: NP_498344.3
• Gene: ugt-66 / 182814
• WormBaseID: WBGene00016013
• Length: 532
• Species: Caenorhabditis elegans
• Alignment Length: 563
• Identity: 130/563 - (23%)
• Similarity: 231/563 - (41%)
• Gaps: 72/563 - (12%)

  Fly     7 LHIFLLSLVALQQLELGTGSRILAAFFFPGKSHFMMTNAIIRELVKQGHEVTFITPFS--LAKEK 69
            ||:..|.|:. |.|.:..  .:|:..|  |.||......:...|.:.||.|||:.|.:  ..|.:
 Worm     4 LHLLFLFLIN-QTLTINV--LVLSPAF--GGSHMNFMAHLADTLTEAGHNVTFLIPVADETRKNQ 63

  Fly    70 LGSNY-KEIVIPQYDFWPEIKEMTNKNTV-----LEM-----TDLPTF--AFLRMVNVMGIHTTD 121
            ||... |::|:.:.|      |:.:::|:     ::|     |..|.|  .|.....:|.:...:
 Worm    64 LGVKITKDVVLVEQD------EIMSRDTLIVDDHMDMMWTLDTHEPNFEEMFSWFNKIMELSCAN 122

  Fly   122 FALEQPEIQAVINEKNKIGKYDLLLAEQFFNEGALILGHLYQI---PTITISTFGNANHLSQLFG 183
            | |...|:..::..:|    :|:.:.|.....|   ||...::   .||..|:....:.:....|
 Worm   123 F-LRNTEVFELMKSRN----FDVAILEPLSVCG---LGFFKKLGIEKTILASSCSLYDFILPDIG 179

  Fly   184 VVSPWSYVPHAYMPYTDRMTLWERIGNVAMSAAEDLVREFSYYPGQDAVLKKHFSKLLDRVPTIK 248
            .....||||.......|:|:.:||..|...|....:..: ..:..:.|:.:.|..|.|   |..:
 Worm   180 EPEDHSYVPSLSSQSGDQMSFYERYKNYRFSRDTKVTMD-RMFDRETAIYRAHLGKDL---PDWR 240

  Fly   249 ELERNISAILLNSYMPLASSRPMAYNMIPVGGLHIQPPK----ALPEHLQKFLDGATHGAIYFSL 309
            .|..:.|....||...|...||:....:.:||:.:...|    .|.:|....||...:..: .|.
 Worm   241 VLLPSASLFFTNSNPYLDFPRPVIQKTVAIGGISVNMGKIKSQKLDDHWDVILDQRNNNML-ISF 304

  Fly   310 GSQVRSADLPPE-KLKVFLEVFGSLKQRVLWKFE--DESLPNLPANVKVQSWLPQGDILAHPNVK 371
            ||.|:|:.:|.: |:.:...:........:||:|  |....:...||....|:||..:|....:.
 Worm   305 GSMVKSSTMPIDWKMNILKVIKSEPNVTFIWKYETNDTKFADGVDNVHFSKWVPQTALLNDDRLT 369

  Fly   372 VFIAHGGLFGTQEAVYNGVPILGMPVYCDQHQNIN---QGKSAEYALGLDYRKVTVEELRGLLME 433
            .|:.||||..|.|..:.|.|.:.:|::.||.:|.|   :...|.:....|.....:  ::..:.:
 Worm   370 AFLTHGGLGSTNELAHWGKPAVTVPIFGDQVRNANMLTRHNGAIFVWKNDLGNYGI--VKEAVHQ 432

  Fly   434 LIENPKYRNNIKKASRIFRDRPLGAMDTAIYWINYVIEHRGAPHLVAAGVHLPWYQFYLLDIVGL 498
            ::.|.||:.|.|..:.|..::|....|..:....::.:....|.:...|..|.::...|.||
 Worm   433 ILYNEKYKRNAKYLADILENQPHQPKDLVVKHTEFLAKFGPFPKMDPYGRSLNFFTRNLFDI--- 494

  Fly   499 GLAVILLPIVVL---------ILICRRSSKPKSTPTKKKTKKN 532
             .|.::....:|         .|:.:.|.|     ..||.||:
 Worm   495 -HAAVVFTYFILATASFNILKFLLSKFSIK-----LVKKAKKD 531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt49B1	NP_611563.1	Glycosyltransferase_GTB-type	38..515	CDD:471961	115/513 (22%)
ugt-66	NP_498344.3	GT1_Gtf-like	19..464	CDD:340817	109/469 (23%)