Protein Alignment Ugt49B1 and ugt-57

DIOPT Version :10

• Sequence 1: NP_611563.1
• Gene: Ugt49B1 / 37420
• FlyBaseID: FBgn0027073
• Length: 532
• Species: Drosophila melanogaster
• Sequence 2: NP_509182.1
• Gene: ugt-57 / 180969
• WormBaseID: WBGene00017154
• Length: 558
• Species: Caenorhabditis elegans
• Alignment Length: 593
• Identity: 155/593 - (26%)
• Similarity: 253/593 - (42%)
• Gaps: 110/593 - (18%)

  Fly    11 LLSLVALQQLELGTGSRILAAFFFPGKSHF--MMTNAIIRELVKQGHEVTFITPFSLAKEKLGSN 73
            |:.|:.|.|:.  |...||.  |..|.:.|  .:...:.::|..:.|.|..|.|..:.:|
 Worm     4 LILLLGLTQIV--TSLNILV--FLLGTNQFERNIFEFLAQQLALRHHNVISIKPVLIPEE----- 59

  Fly    74 YKEIVIPQYDFWPE--IKEMTNKNTVLEMTD-LPTFAFLRMVNVMGIHTTDF--ALEQPEIQA-- 131
             ..:|.|:.....|  ||.:.||:....:.| :|..|:.        .|.||  .|| |..:|
 Worm    60 -PRLVKPKLHLVREKVIKNVLNKDLFKPLEDAVPNAAWR--------STYDFDNYLE-PYYKAHN 114

  Fly   132 -----VINEK--NKIGKYDLLLAEQFFNEGAL-ILGHLYQIPTITISTFGNANHLSQLFG----V 184
                 ::|..  :.:.|..|.||..:.....| .|.||..:|||...|.|..:......|    :
 Worm   115 ASCYKLLNSNLVDSLKKESLDLAIVYSGNPCLNALTHLVAVPTIYFDTEGLTDETLIAAGAPIDL 179

  Fly   185 VSPWSYVPHAYMP----------YTDRMTLW-ERIGNVAMSAAEDLV--------REFSYYPGQD 230
            ::|.|   |.::.          |.:.:..: |.|..:.:.|...||        ...:.....|
 Worm   180 LTPPS---HCFIAESKGYPILNLYKNSVCYFQEMIAQLGLPAVSSLVSSRHRLLDEPITNIFRTD 241

  Fly   231 AVLKKHFSKLLDRVPTIKELERNISAILLNSYMPLASSRPMAYNMIPVGGLHIQPPKALPEHLQK 295
            ..:||.|...    |.:..|::..:|..:|:...|...|.:..|:||||||||..||.|......
 Worm   242 YTIKKRFKNF----PNVNTLKQQSAAYFVNTDPLLEPPRALPLNVIPVGGLHIDHPKPLFSPWNT 302

  Fly   296 FLDGATHGAIYFSLGSQVRSADLPPEKLKVFLEVFGSLKQ-RVLWK------FEDESLPNLPANV 353
            .:..|..|.|..|.|:|..|:.:.....|..|:...:|.. |:.|:      .:...:..:|.::
 Worm   303 TIASAKEGLIIVSFGTQADSSKMSEYHAKAILKALTNLNDYRIYWRIGPNMHLDGIDIEKIPKHI 367

  Fly   354 KVQSWLPQGDILAHPNVKVFIAHGGLFGTQEAVYNGVPILGMPVYCDQHQNINQGKSAEYALGLD 418
            .:.:::||.|:|||.:.|:|:.:||:....|||.:||||:|:|:|.....|:.  |.:...||:.
 Worm   368 NLTTFIPQNDLLAHKSCKLFVTNGGMSSVMEAVAHGVPIVGVPLYGSNRYNLQ--KVSNKGLGIV 430

  Fly   419 YRKVTVEE--LRGLLMELIENPKYRNNIKKASRIFRDRPLGAMDTAIYWINYVIEHRGAPHLVAA 481
            ..|..:.|  |.|.:.:::|:.||:|..|:.|:.|:.|.......|::.|:::..|....::..|
 Worm   431 IDKDDLNEISLYGAMKKVLESAKYKNTAKEMSKEFKSRTTSPFAAALHVIDHIGRHHSFAYMQPA 495

  Fly   482 GVHLPWY---QFYLLDIVGLGLAVILLPIVVLIL---ICRRSSK----------------PKSTP 524
              ..|.|   .||||      |.:||||::.|.|   .|.:||.                ||..|
 Worm   496 --FQPIYTRVDFYLL------LLIILLPVIPLHLFFTFCIKSSAMNVQDNKVLEAERKFLPKKVP 552

  Fly   525 TKKKTKKN 532
               :||||
 Worm   553 ---ETKKN 557

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt49B1	NP_611563.1	Glycosyltransferase_GTB-type	38..515	CDD:471961	136/531 (26%)
ugt-57	NP_509182.1	GT1_Gtf-like	<168..477	CDD:340817	81/317 (26%)