DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt49B1 and ugt-4

DIOPT Version :9

Sequence 1:	NP_611563.1	Gene:	Ugt49B1 / 37420	FlyBaseID:	FBgn0027073	Length:	532	Species:	Drosophila melanogaster
Sequence 2:	NP_001041203.1	Gene:	ugt-4 / 179754	WormBaseID:	WBGene00013905	Length:	535	Species:	Caenorhabditis elegans

Alignment Length:	564	Identity:	124/564 - (21%)
Similarity:	230/564 - (40%)	Gaps:	100/564 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 SRILAAFFFP------------------GKSHFMMTNAIIRELVKQGHEVTFITPF----SLAKE 68
            ||:|....|.                  |.||......|..:|..:||:||:..||    .|..:
Worm     2 SRVLCVLLFSVLVSHVESYKFLVISPVYGYSHMKFMAIIANQLADEGHQVTYFQPFVIEAYLDHK 66

  Fly    69 KLGSNYKEIV-----------IPQ----YDFWPEIKEMTNKNTVLEMTDLPTFAFLRMVNVMGIH 118
            .|.::..:::           ||.    :|.|...|..:..:.|.:|......|:..|...:
Worm    67 LLNNSLIDVINYWHDEEGRRHIPPSNDLHDAWYSSKYQSALSAVFDMPQFLVSAWEHMCRKI--- 128

  Fly   119 TTDFALEQPEIQAVINEKNKIGKYDLLLAEQFFNEGALILGHLYQIPTITISTFGNANHLSQLFG 183
                 .:..|:..::.:|:    :|:::||.|...|..:..::.....:::.|......::...|
Worm   129 -----FQDSELHKILKDKD----FDVVIAETFDFCGLYLADYIQSKSIVSVFTGSRLIAITDPLG 184

  Fly   184 VVSPWSYVPHAYMPYTDRM----TLWERIGNVAMSAAEDLVREFSYYPGQDAVLKKHFSKLL--- 241
            ..|...|:|   .|.:|..    ::::||        .||..::.:..|...:....::::.
Worm   185 EPSSLHYIP---APSSDNFGSSASIFDRI--------NDLYHKYVFGSGYSIIFDWQYNQIARLT 238

  Fly   242 -DRVPTIKELERNISAILLNSYMPLASSRPMAYNMIPVGGLHIQP--PKALPEHLQKFLDGATHG 303
             .:|...|::.::::....||...|..:.|....:||:||..:..  ...:|:.....|:..:.
Worm   239 HGKVRHWKKILKDVTYHFANSNPYLDFAAPTISKVIPIGGYDMDKSIQTKIPDEFDSILNERSL- 302

  Fly   304 AIYFSLGSQVRSADLPPEKLKVFLEVFGSLKQRV--LWKFEDES----LPNLPANVKVQSWLPQG 362
            .:|.|.||.|::..:|....:..|.:|.:..|.:  |||:||.:    ...||.||.::.|.||.
Worm   303 TVYVSFGSMVKAKFMPESYKEAMLRMFTANTQNITFLWKYEDPTDIFFKNRLPKNVILKDWFPQR 367

  Fly   363 DILAHPNVKVFIAHGGLFGTQEAVYNGVPILGMPVYCDQHQNINQGK------SAEYALGLDYRK 421
            .:||...||:||.||||..|.|..|...|.:.:|:..:|..|   ||      |||.     |.|
Worm   368 ALLADKRVKLFITHGGLGSTMELAYAAKPAIVIPLIAEQPDN---GKMLARHGSAEI-----YSK 424

  Fly   422 VTV---EELRGLLMELIENPKYRNNIKKASRIFRDRPLGAMDTAIYWINYVIEHRGAPHLVAAGV 483
            ..:   |:|..||.:::::..|:....:.:|:..::|:...:..|............|.|..:..
Worm   425 HDIPHWEKLNRLLQKMLQHSSYQKAADRLARVLSNQPIKPRELMIKHSEMAAMFGKMPELTPSVQ 489

  Fly   484 HLPWYQFYLLD------IVGLGLAVILLPIVVLILICRRSSKPK 521
            .:...:||.||      |:.:|.:|:|...:..:|....|.|.|
Worm   490 DMSIIEFYNLDIIFLFLIISIGTSVLLWKFLYFVLTDSGSFKSK 533

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt49B1	NP_611563.1	egt	7..513	CDD:223071	120/554 (22%)
Ugt49B1	NP_611563.1	UDPGT	38..515	CDD:278624	116/526 (22%)
ugt-4	NP_001041203.1	egt	1..473	CDD:223071	110/502 (22%)
ugt-4	NP_001041203.1	UDPGT	21..500	CDD:278624	110/510 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160161534
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.740