Protein Alignment Ugt49B1 and ugt-48

DIOPT Version :10

• Sequence 1: NP_611563.1
• Gene: Ugt49B1 / 37420
• FlyBaseID: FBgn0027073
• Length: 532
• Species: Drosophila melanogaster
• Sequence 2: NP_504464.2
• Gene: ugt-48 / 178940
• WormBaseID: WBGene00015965
• Length: 526
• Species: Caenorhabditis elegans
• Alignment Length: 576
• Identity: 152/576 - (26%)
• Similarity: 240/576 - (41%)
• Gaps: 108/576 - (18%)

  Fly    11 LLSLVALQQLELGTGSRILAAFFFP--GKSHFMMTNAIIRELVKQGHEVTFITPFSLAKEKLGSN 73
            :|:.:|:.|:.  |..:||  .|.|  .|||.:....|..||...||||....|..|       |
 Worm     5 ILTFLAVCQVT--TSHKIL--MFSPTASKSHMISQGRIADELANAGHEVVNFEPDFL-------N 58

  Fly    74 YKEIVIP--QYDFWPEIKEMTNKNTVLEMTDLPTFAFLRMVNVMG------------IHTTDFAL 124
            ..:..:|  :...||             :|.|..:.|.::.|.:.            |..||...
 Worm    59 LTDKFVPCKKCRRWP-------------VTGLNNYKFKKIQNGLSGDVFQQSSIWSKIFNTDSDP 110

  Fly   125 EQPEI-----QAVIN----EKNKIGKYDLLLAEQFFNEG---ALILG--HLYQIPTITISTFGNA 175
            .|.|.     :.|.|    ||.|..|:|....||....|   |.::|  |.:.|.:.|:|.
 Worm   111 YQDEYTNMCEEMVTNKELIEKLKKEKFDAYFGEQIHLCGMGLAHLIGIKHRFWIASCTMSV---- 171

  Fly   176 NHLSQLFGVVSPWSYVPHAYMPYTDR--MTLWERIGNVAMSAAEDLVREFSYYPGQDAVL----- 233
             .:....|:.:|.|.:|  :|...|.  ...|:|..|..:..|.  :|: .|   :|.||
 Worm   172 -SMRDSLGIPTPSSLIP--FMSTLDATPAPFWQRAKNFVLQMAH--IRD-EY---RDVVLTNDMF 227

  Fly   234 KKHFSKLLDRVPTIKELERNISAILLNSYMPLASSRPMAYNMIPVGGLHIQPP-KALPEHLQKFL 297
            ||:|.   ...|.::.|.:....|.:::...|....|...|::.:|||.:... ..|.|...|.:
 Worm   228 KKNFG---SDFPCVEFLAKTSDLIFVSTDELLEIQAPTLSNVVHIGGLGLSSEGGGLDEKFVKIM 289

  Fly   298 DGATHGAIYFSLGSQVRSADLPPEKLKVFLEVFGSLKQR----VLWKFEDES--LPNLPANVKVQ 356
            :.. .|.|.||||:...:.:|||..::..:::....|..    .:.||:..|  |....:||.|.
 Worm   290 EKG-KGVILFSLGTIANTTNLPPTIMENLMKITQKFKDYEFIIKVDKFDRRSFDLAEGLSNVLVV 353

  Fly   357 SWLPQGDILAHPNVKVFIAHGGLFGTQEAVYNGVPILGMPVYCDQHQNINQGKSAE--------- 412
            .|:||..:||||.:|.||.|.|.....|:.|.|||::.:|...||.:|   |:|.|
 Worm   354 DWVPQTAVLAHPRLKAFITHAGYNSLMESAYAGVPVILIPFMFDQPRN---GRSVERKGWGILRD 415

  Fly   413 -YALGLDYRKVTVEELRGLLMELIENPKYRNNIKKASRIFRDRPLGAMDTAIYWINYVIEHRGAP 476
             :.|..|     .:.:.|.:.|::.||.|:....:..::.|.:|..|.:..:...|:|:|:.|..
 Worm   416 RFQLIKD-----PDAIEGAIKEILVNPTYQEKANRLKKLMRSKPQSASERLVKMTNWVLENDGVE 475

  Fly   477 HLVAAGVHLPWYQFYLLDIVGLGLAVILLPIVVLILICRRSSKPKSTPTKKKTKKN 532
            .|...|.|:.::.||.|||:     :....|.|||.|..|.|......:..|.||:
 Worm   476 ELQYEGKHMDFFTFYNLDII-----ITAASIPVLIFIVLRISNISIITSSPKNKKD 526

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt49B1	NP_611563.1	Glycosyltransferase_GTB-type	38..515	CDD:471961	138/528 (26%)
ugt-48	NP_504464.2	GT1_Gtf-like	19..451	CDD:340817	123/478 (26%)