Protein Alignment Ugt49B1 and ugt-12

DIOPT Version :10

• Sequence 1: NP_611563.1
• Gene: Ugt49B1 / 37420
• FlyBaseID: FBgn0027073
• Length: 532
• Species: Drosophila melanogaster
• Sequence 2: NP_504309.1
• Gene: ugt-12 / 178880
• WormBaseID: WBGene00020592
• Length: 534
• Species: Caenorhabditis elegans
• Alignment Length: 563
• Identity: 144/563 - (25%)
• Similarity: 236/563 - (41%)
• Gaps: 79/563 - (14%)

  Fly    20 LELGTGSRILAAFFFP-------------GKSHFMMTNAIIRELVKQGHEVTFITPFSLAKEKLG 71
            :.|||...:|...||.             |.||....:.:...:...||.||...|:.:|.:.|.
 Worm     1 MRLGTFIFLLTFLFFECYSSKILIFNPIFGFSHVKFISKMADIIADHGHHVTLFQPYHIALKNLD 65

  Fly    72 SNYKEIVIPQYDFWPEIKEMTNKNTVLEMTDLPTFAF--------------LRMVNVMGIHTTDF 122
            ...|...|...::.|     |:...:|: .:..||:|              ..|..::|......
 Worm    66 GLVKNKNIEILNYHP-----THYEELLK-AEPQTFSFFWDSYLVGNPVIGAFLMPKLLGGEFKKT 124

  Fly   123 ALEQPEIQAVINEKNKIGKYDLLLAEQFFNEGALILGHLYQIPTITISTFGNANHLSQLFGVVSP 187
            |:|....|.:|||. |..|:||::||.|...| ..|.||..:|.|.:.:.......:..||..|.
 Worm   125 AMEVLSDQKLINEL-KDRKFDLVIAETFELTG-FYLAHLLDVPCIPMMSAVRYPIFNDQFGQPSL 187

  Fly   188 WSYVPHAYMPYTDRMTLWERIGNV----AMSAAEDLVREFSYYPGQDAVLKKHFSKLLDRVPTIK 248
            ..:||............::|:.::    .|..:::.:.::..|..::|:.:.        ||..|
 Worm   188 LGHVPQIGSAVAGEAGFYDRLNDMFRFFFMGISQEQLNKYQNYFIEEAIGRP--------VPFWK 244

  Fly   249 ELERNISAILLNSYMPLASSRPMAYNMIPVGGLHIQPPK-----ALPEHLQKFLDGATHGAIYFS 308
            :|.:.....:.||...|..:.|....::.|||:.:...|     .|||..:..|. .....:..|
 Worm   245 DLVKQSPIYITNSNPYLDYAVPSTAAIVQVGGITMDLKKLKQVGELPEEYENILK-ERESTVLIS 308

  Fly   309 LGSQVRSADLPPEKLKVFLEVFGSLKQ-RVLWKFEDESL---PNLPANVKVQSWLPQGDILAHPN 369
            .||.:||.::|.......::||.||.. ..:||:|.:.|   ..||.||.::.|:||..:||...
 Worm   309 FGSVIRSYEMPESFKAGLIKVFESLPDVTFIWKYEKDDLEFQKRLPKNVHLKKWIPQPSLLADKR 373

  Fly   370 VKVFIAHGGLFGTQEAVYNGVPILGMPVYCDQHQNINQGKSAEYALGLDYRKVTV---EELRGLL 431
            ||:||.||||..|.|..|.|.|.:.:|::.|||.|...  .|.:...:.|.|..:   |:|..::
 Worm   374 VKLFITHGGLGSTMEVAYTGKPAIVVPIFGDQHHNAVM--LARHGGAVAYDKFDLKNGEKLTAVV 436

  Fly   432 MELIENPKYRNNIKKASRIFRDRP-------LGAMDTAIYWINYVIEHRGAPHLVAAGVHLPWYQ 489
            .|:|.:.||:.|.:....:..::|       |..:|.||.:.|    ||..   |.|...|.:..
 Worm   437 HEMISSTKYQENAEALQHVLFNQPIDPKMNFLNHLDFAIKFPN----HRAQ---VPAINQLGFVA 494

  Fly   490 FYLLDIVGLGLAVILLPIVVLILICRRSSKPKSTPTKKKTKKN 532
            .|.||::   |.:::..||:..|......|.......||||.:
 Worm   495 HYYLDVL---LFLLVSSIVITYLAISLLKKVLGKCLTKKTKSD 534

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt49B1	NP_611563.1	Glycosyltransferase_GTB-type	38..515	CDD:471961	132/513 (26%)
ugt-12	NP_504309.1	GT1_Gtf-like	21..456	CDD:340817	115/453 (25%)