Protein Alignment Ugt49B1 and ugt-22

DIOPT Version :10

• Sequence 1: NP_611563.1
• Gene: Ugt49B1 / 37420
• FlyBaseID: FBgn0027073
• Length: 532
• Species: Drosophila melanogaster
• Sequence 2: NP_502633.1
• Gene: ugt-22 / 178330
• WormBaseID: WBGene00007455
• Length: 534
• Species: Caenorhabditis elegans
• Alignment Length: 520
• Identity: 145/520 - (27%)
• Similarity: 232/520 - (44%)
• Gaps: 42/520 - (8%)

  Fly    10 FLLSLVALQQLELGTGS--RILAAFFFPGKSHFMMTNAIIRELVKQGHEVTFITP---FSLAKEK 69
            |||.|:.|....:|...  :||......|.||..|..|:...|...||::|.:.|   |....:.
 Worm     6 FLLPLLLLLGSFVGLTEPYKILMYTNLFGHSHIKMLGAVSDTLTDAGHDLTVLMPVIDFKQENKT 70

  Fly    70 LGSNYKEI--VIPQYDFWPEIKEMTNKNTVLEMTD--LPTFAFLRMVNVMGIHTTDF--ALEQPE 128
            ...:.|.|  :.|..|....|:.|....|.|..||  .|.|.......:..|..:..  .||..|
 Worm    71 AMKSTKNIIKIQPGQDISKTIETMEKFMTQLWTTDNSNPLFMVFHAPAMSAIFASQCRKVLEDKE 135

  Fly   129 IQAVINEKNKIGKYDLLLAEQF------FNEGALILGHLYQIPTITISTFGNANHLSQLFGVVSP 187
            :...:..:|    :||.:.|.|      ..|...|..|      :.:.:....:|:|:..|....
 Worm   136 LIERLRAEN----FDLAITEPFDTCAYALFEAIKIRAH------VAVLSCSRLDHVSKAIGQPIA 190

  Fly   188 WSYVPHAYMPYTDRMTLWERIGNVAMSAAEDLVREFSYYPGQDAVLKKHFSKLLDRVPTIKELER 252
            .||||.....:.:|||:|:|..|:......|.:  |||...:|..:.|   :::..|.:.:|:..
 Worm   191 PSYVPGTQSTHGERMTIWQRFMNILHFLMGDFL--FSYIGDEDFKVAK---EIIPGVRSWREVLP 250

  Fly   253 NISAILLNSYMPLAS-SRPMAYNMIPVGGLHIQPPK---ALPEHLQKFLDGATHGAIYFSLGSQV 313
            ..|.|..| ::||.. ..|....:||:||:.::..|   .|||...|.| |.....|..|.||..
 Worm   251 EASFIFTN-HIPLMDFPAPTFDKIIPIGGISVKTQKKSLELPEKWNKIL-GLRKKNILVSFGSNA 313

  Fly   314 RSADLPPEKLKVFLEVFGSLKQ-RVLWKFEDE--SLPNLPANVKVQSWLPQGDILAHPNVKVFIA 375
            ||||:|....:..|:|..|:.. ..:||:|:|  :|.:...||.:..||||.::|..|.:.:|:.
 Worm   314 RSADMPEHFKQNVLKVAESMPDVTFIWKYENEKDTLADHLDNVYLGDWLPQNELLGDPRLSLFVT 378

  Fly   376 HGGLFGTQEAVYNGVPILGMPVYCDQHQNINQGKSAEYALGLDYRKV-TVEELRGLLMELIENPK 439
            ||||....|....|.|.:.:|::.||.:|.|..|....|..|....: ..|.:|..:.:::||.|
 Worm   379 HGGLASVTELALMGKPAVMVPLFADQARNANMLKRHGGAAVLHKTDLGNAETIRNTIKKVLENEK 443

  Fly   440 YRNNIKKASRIFRDRPLGAMDTAIYWINYVIEHRGAPHLVAAGVHLPWYQFYLLDIVGLGLAVIL 504
            ||.|.::.:.:..::|....||.|..:.:..:....|.:...|.|..:.::|||||:.:.|.:||
 Worm   444 YRVNAERLAEMLNNQPTNPKDTLIKHVEFAAKFGQLPSMDPYGRHQSYIEYYLLDIISIALVLIL 508

  Fly   505  504
             Worm   509  508

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt49B1	NP_611563.1	Glycosyltransferase_GTB-type	38..515	CDD:471961	136/490 (28%)
ugt-22	NP_502633.1	GT1_Gtf-like	24..469	CDD:340817	128/461 (28%)