Protein Alignment Ugt49B1 and ugt-52

DIOPT Version :10

• Sequence 1: NP_611563.1
• Gene: Ugt49B1 / 37420
• FlyBaseID: FBgn0027073
• Length: 532
• Species: Drosophila melanogaster
• Sequence 2: NP_499988.1
• Gene: ugt-52 / 176904
• WormBaseID: WBGene00018931
• Length: 541
• Species: Caenorhabditis elegans
• Alignment Length: 525
• Identity: 135/525 - (25%)
• Similarity: 234/525 - (44%)
• Gaps: 50/525 - (9%)

  Fly     9 IFLLSLV-ALQQLELGTGSRILAAFFFPGKSHFMMTNAIIRELVKQGHEVTFITPFSLAKEKLGS 72
            :||.:|. .:|.|      .:|......||||...|:::|..||:.||.|..|  .:.....:.|
 Worm    20 VFLFTLPRVIQTL------HVLFYILLLGKSHIDFTDSLIESLVENGHTVDLI--IARMNSHVKS 76

  Fly    73 NYKEIVIPQYDF-------WPEIKEMTNKNTVLEMTDLPTFAFLRMVNVMGIHTTDFALEQPEIQ 130
            |...:|..:|.:       |.:...:.|.....|.|......::.:|..:    .:..|....:.
 Worm    77 NGTNMVTRKYTYGFQEESPWNKAPHLLNPFKGRERTWNEHTYYMDIVTDL----CEIGLSDAGLH 137

  Fly   131 AVINEKNKIGKYDLLLAEQFFNEGALILGHLYQIPTI-TISTFGNANHLSQLFGVV-SPWSYVPH 193
            |.|:.:    |||:.:|.::.|.|..::.: |:||:| ::|:....:..|...|:. ||  .|..
 Worm   138 AFISSQ----KYDIGIATEYENCGVALMKY-YKIPSIVSVSSLPILDRQSLAAGMPNSP--AVTQ 195

  Fly   194 AYMPYTDRMTLWERIGNVAMSAAEDLVREFSYYPGQDAVLKKHFSKLLDRVPTIKELERNISAIL 258
            |.....|..|.|.:..|....|...|:........|..|:|||..:..|....|:.|:    ...
 Worm   196 AIFEAEDLTTYWGKFRNFLNWAHITLIINPYCEKHQSEVIKKHLGENFDTSNLIESLD----LAF 256

  Fly   259 LNSYMPLASSRPMAYNMIPVGGLHIQPPK-ALPEHLQKFLDGAT--HGAIYFSLGSQVRSADLPP 320
            :||...:.:.|..::.:..:||::::..| .|.|.::|.:....  :|.:.|..|:||.|:..|.
 Worm   257 VNSNELIETPRVSSHKIKYIGGINLKKSKDRLDEEVEKVITQKPIGNGIVVFCFGTQVPSSLFPI 321

  Fly   321 EKLKVFLEVFGSLKQ-RVLWKFE----DESLPNLPANVKVQSWLPQGDILAHPNVKVFIAHGGLF 380
            |..:.|.:.|..... ..:||:|    ||.:.....|:::..||||.|:|.....|.||:|.||.
 Worm   322 EVRRAFAQAFRHFPDFTFVWKYEMQDGDEQIFANTTNLRLLKWLPQTDLLNDARTKAFISHVGLN 386

  Fly   381 GTQEAVYNGVPILGMPVYCDQHQNINQGKSAEYALGLDYRKVTVEELRGLLMELIENPKYRNNIK 445
            ...|:.|.|||||.:|::.||..|...|.|......||..::|...:...|..::.:..|..|.|
 Worm   387 SYLESSYAGVPILAVPLFADQPHNAFSGMSIGTTYMLDKTRLTTPNIVKGLEAVLYDSSYTLNAK 451

  Fly   446 KASRIFRDRPLGAMDTAIYWINYV----IEHRGAPHLVAAGVHLPWYQFYLLDIVGLGLAVILLP 506
            :.|::..:||.......:.||.:.    :.||   :|...|.::..:::|.|||:  ...::||.
 Worm   452 RISKMLHERPNPPKKIFVEWIEFASRNPLLHR---NLNLIGQNMSVFEYYCLDII--SFCILLLS 511

  Fly   507 IVVLI 511
            ||:.:
 Worm   512 IVISV 516

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt49B1	NP_611563.1	Glycosyltransferase_GTB-type	38..515	CDD:471961	127/495 (26%)
ugt-52	NP_499988.1	GT1_Gtf-like	32..460	CDD:340817	115/450 (26%)