Protein Alignment Ugt49B1 and ugt-25

DIOPT Version :10

• Sequence 1: NP_611563.1
• Gene: Ugt49B1 / 37420
• FlyBaseID: FBgn0027073
• Length: 532
• Species: Drosophila melanogaster
• Sequence 2: NP_491438.1
• Gene: ugt-25 / 172087
• WormBaseID: WBGene00015692
• Length: 531
• Species: Caenorhabditis elegans
• Alignment Length: 540
• Identity: 130/540 - (24%)
• Similarity: 226/540 - (41%)
• Gaps: 79/540 - (14%)

  Fly    36 GKSHFMMTNAIIR---ELVKQGHEVTFITPFS--LAKEKLG-SNYKEIVIPQYD----------- 83
            |.||   ||.:.|   .|.:.||.|||:.|.:  ..|.:|| ...|::||.:.|
 Worm    28 GGSH---TNFMARLADTLTEAGHNVTFVVPVADEARKGQLGVKKTKDVVIVEQDELMKSEIKPLD 89

  Fly    84 -----FWPEIKEMTNKNTVLEMTD----LPTFAFLR---MVNVMGIHTTDFALEQPEIQAVINEK 136
                 :|....:.:|.:::..:..    |....|:|   :.|.:.....|..:.:|.....:...
 Worm    90 DDMAQYWETDMDSSNADSIFSVFSDAMLLSCNNFMRNKKVFNELKSRNFDVGIYEPLSVCGLGYM 154

  Fly   137 NKIGKYDLLLAEQFFNEGALILGHLYQIPTITISTFGNANHLSQLFGVVSPWSYVPHAYMPYTDR 201
            :.||...|:::    :..||..|        |::..|..          ..:||||.:.....::
 Worm   155 HAIGINKLIMS----SSCALYDG--------TVAAIGEP----------IDFSYVPGSMSKSGEK 197

  Fly   202 MTLWERIGNVAMSAAEDLVREFSYYPGQDAVLKKHFSKLLDRVPTIKELERNISAILLNSYMPLA 266
            |:|:|::.|..:|.|...: ::..:..:..:.|||   |.:.:|..::|..:.|....||...:.
 Worm   198 MSLFEKLENYRLSMASSRM-QYGQWDKETEIYKKH---LGNDIPHWRDLMPSSSVAFTNSIPYVD 258

  Fly   267 SSRPMAYNMIPVGGLHIQPPKALPEHL----QKFLDGATHGAIYFSLGSQVRSADLPPEKLKVFL 327
            ..|.:....:|:||:.:.......:.|    ...||...|..: .|.||.|||.|:|.:.....|
 Worm   259 FPRSITQKTVPIGGISVDMEMIKSQKLSIEWSTVLDERPHNML-ISFGSMVRSMDMPLKWRNGLL 322

  Fly   328 EVFGSLKQ-RVLWKFEDESLPNLPA--NVKVQSWLPQGDILAHPNVKVFIAHGGLFGTQEAVYNG 389
            |...|... ..:||:|:::|.....  |:....|:||..:|....:..|:.||||..|.|..:.|
 Worm   323 EAIKSEPNVTFIWKYENDNLEWAKGIQNIYFSKWVPQTALLNDARLTAFMTHGGLGSTNELAFLG 387

  Fly   390 VPILGMPVYCDQHQNINQ-----GKSAEYALGLDYRKVTVEELRGLLMELIENPKYRNNIKKASR 449
            .|.|.:||:.||.:|.|.     |....:...|...|.....:|.:|.|    .||:.|.:|.|.
 Worm   388 KPALMVPVFADQDRNANMLARHGGVLVVHKKELGNFKTIKSSIRSILHE----EKYQKNARKLSE 448

  Fly   450 IFRDRPLGAMDTAIYWINYVIEHRGAPHLVAAGVHLPWYQFYLLDIVGLGLAVILLPIVVLILIC 514
            :..::||...:..:.:..:|.:....|.:.:.|..|.:.|..|:||.. .:::..|.::.||...
 Worm   449 LLNNQPLKPKEQVVKYTEFVAKFGPFPQMDSYGRQLGFIQRNLIDIYA-AISLSYLFVISLIYFV 512

  Fly   515 RRSSKPKSTPTK--KKTKKN 532
            .:....| ||.|  |..||:
 Worm   513 FKFVISK-TPLKLVKLVKKD 531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt49B1	NP_611563.1	Glycosyltransferase_GTB-type	38..515	CDD:471961	122/517 (24%)
ugt-25	NP_491438.1	GT1_Gtf-like	19..464	CDD:340817	112/469 (24%)