Protein Alignment Ugt49B1 and Ugt2b37

DIOPT Version :10

• Sequence 1: NP_611563.1
• Gene: Ugt49B1 / 37420
• FlyBaseID: FBgn0027073
• Length: 532
• Species: Drosophila melanogaster
• Sequence 2: NP_444445.2
• Gene: Ugt2b37 / 112417
• MGIID: 2148239
• Length: 530
• Species: Mus musculus
• Alignment Length: 523
• Identity: 162/523 - (30%)
• Similarity: 257/523 - (49%)
• Gaps: 55/523 - (10%)

  Fly    38 SHFMMTNAIIRELVKQGHEVTFITPFSLAKEKLGSNYKEIVIPQYDFWPEIKEMTNKNTVLEMTD 102
            ||:|....|:.|||::|||||.:.|         |.| .::.|:..  |.:|..|...:|.: .|
Mouse    34 SHWMNIKIILDELVQRGHEVTVLRP---------SAY-YVLDPKKS--PGLKFETFPTSVTK-DD 85

  Fly   103 LPTFAFLRMVNVMGIH-TTDFALE-QPEIQAVINE--------------------KNKIGKYDLL 145
            |..| |::::||.... :.|..|. .|.:|.:.:|                    |.:..|:|:|
Mouse    86 LENF-FIQLLNVWTYELSRDTCLSYSPLMQNMFDELSGYYLSLCKDVVSNRQLMTKLQESKFDVL 149

  Fly   146 LAEQFFNEGALILGHLYQIPTITISTFGNANHLSQLFG-VVSPWSYVPHAYMPYTDRMTLWERIG 209
            |::.....|.|| ..|..||.:....|.....:.:..| .:.|.||||........:||..||:.
Mouse   150 LSDPVAFGGELI-AELLHIPFLYSLRFTAGYRIEKSSGRFLLPPSYVPVILSGLGGQMTFIERVK 213

  Fly   210 NVAMSAAEDLVREFSYYPGQDAVLKKHFSKLLDRVPTIKELERNISAILLNSYMPLASSRPMAYN 274
            |:...    |..:|.:....|......:::.|.|..|:.|........|:.|...|....|...|
Mouse   214 NMICM----LYFDFWFQMPNDKKWDSFYTEYLGRPTTLAETMGQAEMWLIRSNWDLEFPHPTLPN 274

  Fly   275 MIPVGGLHIQPPKALPEHLQKFLDGA-THGAIYFSLGSQVRSADLPPEKLKVFLEVFGSLKQRVL 338
            :..|||||.:|.|.||:.:::::..: .||.:.|||||.|  :::..||:.........:.|:||
Mouse   275 VDYVGGLHCKPAKPLPKDMEEYVQSSGDHGVVVFSLGSMV--SNITEEKVNAIAWALAQIPQKVL 337

  Fly   339 WKFEDESLPNLPANVKVQSWLPQGDILAHPNVKVFIAHGGLFGTQEAVYNGVPILGMPVYCDQHQ 403
            |||:.::...|..|.:|..||||.|:|.||..|.||.|||.....||:|:|:|::|:|::.:||.
Mouse   338 WKFDGKTPATLGHNTRVYKWLPQNDLLGHPKTKAFITHGGANSVYEAIYHGIPMIGIPLFGEQHD 402

  Fly   404 NINQGKSAEYALGLDYRKVTVEELRGLLMELIENPKYRNNIKKASRIFRDRPLGAMDTAIYWINY 468
            ||....:...|:.|:.|.::..::...|.|:||||.|:.|....|.|..|:|:..:|.|::|:.:
Mouse   403 NIAHMVAKGAAVTLNIRTMSRSDVLNALEEVIENPFYKKNAMWLSTIHHDQPMKPLDRAVFWVEF 467

  Fly   469 VIEHRGAPHLVAAGVHLPWYQFYLLDIVGLGL----AVILLPIVVLILICRRSSKPKSTPTKKKT 529
            |:.|:.|.||...|.:|.|||::.||::|..|    |.::|.:..|:.|.|      ...||||.
Mouse   468 VMRHKNAKHLRPLGHNLTWYQYHSLDVIGFLLACVAATVVLTVKCLLFIYR------FFVTKKKK 526

  Fly   530 KKN 532
            .||
Mouse   527 MKN 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt49B1	NP_611563.1	Glycosyltransferase_GTB-type	38..515	CDD:471961	155/504 (31%)
Ugt2b37	NP_444445.2	UDPGT	24..527	CDD:278624	160/519 (31%)