Protein Alignment Ugt49B1 and Ugt3a2

DIOPT Version :10

• Sequence 1: NP_611563.1
• Gene: Ugt49B1 / 37420
• FlyBaseID: FBgn0027073
• Length: 532
• Species: Drosophila melanogaster
• Sequence 2: NP_997099.2
• Gene: Ugt3a2 / 105887
• MGIID: 2146055
• Length: 523
• Species: Mus musculus
• Alignment Length: 541
• Identity: 145/541 - (26%)
• Similarity: 252/541 - (46%)
• Gaps: 76/541 - (14%)

  Fly    10 FLLSLVALQQLELGTGSRILAAFFFPGKSHFMMTNAIIRELVKQGHEVTFITPFSLAKE------ 68
            |||.::.|:..::.|.|.:.|       ||:::.|.:.:.|...||:|     ..|..|
Mouse    13 FLLEVLLLEAAKILTISTLSA-------SHYILMNRVSQILQGGGHDV-----IKLLYEGGDIPD 65

  Fly    69 --KLGSNYKEIVIPQYDFW--PEIKEMTNKNTVLEMTDLPTFAFLRMVNVMGIHTTDFA------ 123
              |..|:|:.|      .|  ||.::.|.:|....:.|...:...:...::.||.. ||
Mouse    66 FRKENSSYQVI------NWRLPEDQQKTFENRWHRLIDEYAYGRSKYHTLLKIHQY-FADLCSHL 123

  Fly   124 LEQPEIQAVINEKNKIGKYDLLLAEQFFNEGALILGHLYQ-----IP-TITISTFGNANHLSQLF 182
            |.:.:|..::.::|    :||:|.:.......||:..|.:     :| ..:...||..|
Mouse   124 LSRKDIMELLQKEN----FDLVLLDSMDLCSFLIVEKLGKRFVSFLPFQFSYMDFGLPN------ 178

  Fly   183 GVVSPWSYVPHAYMPYTDRMTLWERIGNVAM-----SAAEDLVREFSYYPGQDAVLKKHFSKLLD 242
               :|.||.|......||:|..|.|:.|:.|     ....|:   ||.|..   .:::||::  .
Mouse   179 ---APLSYAPVYGSGLTDQMDFWGRVKNILMFFHFTKKRRDI---FSQYGN---TVQEHFAE--G 232

  Fly   243 RVPTIKELERNISAILLNSYMPLASSRPMAYNMIPVGGLHIQPPKALPEHLQKFLDG-ATHGAIY 306
            ..|.:.:|........:||...|..:||:..|.:.||||..:|.:.:|:.|:.|:.. ...|.:.
Mouse   233 SQPVLSDLLLKAELWFVNSDFALDFARPLFPNTVYVGGLLDKPVQPIPQDLEDFISQFGDSGFVL 297

  Fly   307 FSLGSQVRSADLPPEKLKVFLEVFGSLKQRVLWKFEDESLP---NLPANVKVQSWLPQGDILAHP 368
            .:|||.| |.....|.:|.....|..|.|.|||..:....|   :|..|||:..||||.|:||||
Mouse   298 VALGSVV-SMIQSKEIIKEMNSAFAHLPQGVLWTCKSSHWPKDVSLAPNVKIMDWLPQIDLLAHP 361

  Fly   369 NVKVFIAHGGLFGTQEAVYNGVPILGMPVYCDQHQNINQGKSAEYALGLDYRKVTVEELRGLLME 433
            ::::|:.|||:....|||::|||::|:|.:.||.:|:.:.::....:.:..:.:..|.....:.|
Mouse   362 SIRLFVTHGGMNSVMEAVHHGVPMVGIPFFGDQPENMVRVEAKNLGVSIQLQTLKAESFLLTMKE 426

  Fly   434 LIENPKYRNNIKKASRIFRDRPLGAMDTAIYWINYVIEHRGAPHLVAAGVHLPWYQFYLLDI--- 495
            :||:.:|:.....:..|.:..||......:.||:::::..||.||.......||::.|:||:
Mouse   427 VIEDQRYKTAAMASKVIRQSHPLTPAQRLVGWIDHILQTGGAAHLKPYAFQQPWHEQYMLDVFLF 491

  Fly   496 -VGLGLAVILLPIVVLILICR 515
             :||.|..:.|.:.||:.:.|
Mouse   492 LLGLTLGTLWLSVKVLVAVTR 512

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt49B1	NP_611563.1	Glycosyltransferase_GTB-type	38..515	CDD:471961	137/511 (27%)
Ugt3a2	NP_997099.2	Glycosyltransferase_GTB-type	24..488	CDD:471961	133/504 (26%)