Protein Alignment Ugt49B1 and Ugt2b34

DIOPT Version :10

• Sequence 1: NP_611563.1
• Gene: Ugt49B1 / 37420
• FlyBaseID: FBgn0027073
• Length: 532
• Species: Drosophila melanogaster
• Sequence 2: NP_705826.1
• Gene: Ugt2b34 / 100727
• MGIID: 2140962
• Length: 532
• Species: Mus musculus
• Alignment Length: 555
• Identity: 165/555 - (29%)
• Similarity: 277/555 - (49%)
• Gaps: 54/555 - (9%)

  Fly     1 MSLKSALHIFLLSLVALQQLELGTGSRILAAFFFPGK-SHFMMTNAIIRELVKQGHEVTFITP-F 63
            :.:.:||.:.||.|...  ...|||.::|.   :|.: ||::....|:.||:|:||||..:.| .
Mouse     3 VKMTAALLLLLLQLSGF--FGSGTGGKVLV---WPMEFSHWLNLKTILDELLKKGHEVMVLRPSA 62

  Fly    64 SLAKEKLGSNYKEIVIPQYD-----------FWPEIKEMTNKNTVLEMTDLPTFA----FLRMVN 113
            ||:.|.  .|...|....|.           ||..:|:.        :.:||..:    ||.:..
Mouse    63 SLSYEV--DNTSAIEFETYPTSYSLSELEEIFWESLKKY--------IYELPKQSFWGYFLMLQE 117

  Fly   114 VMGIHTTDFALEQPEIQAVINE----KNKIGKYDLLLAEQFFNEGALILGHLYQIPTI-TISTFG 173
            ::.:.:..|  |......|.|:    |.:..::|::||:.|...|.| |..:.:||.: ::..|.
Mouse   118 MVWVDSKYF--ESLCKDVVFNKELMTKLQKSRFDVILADPFIPCGDL-LAEVLKIPLVYSLRFFP 179

  Fly   174 NANHLSQLFGVVSPWSYVPHAYMPYTDRMTLWERIGNVAMSAAEDLVREFSYYPGQDAVLKKHFS 238
            .:.:.....|:..|.||||......:||||..||:.||...    |..:|.:....:....:.::
Mouse   180 GSTYEKYSGGLPLPPSYVPVVMSELSDRMTFMERVRNVIYM----LCFDFWFQTFNEKNWNQLYT 240

  Fly   239 KLLDRVPTIKELERNISAILLNSYMPLASSRPMAYNMIPVGGLHIQPPKALPEHLQKFLDGA-TH 302
            ::|.|..|:.|........|:.:|..|....|:..|...:||||.:|.|.||:.::.|:..: .|
Mouse   241 EVLGRPTTLSETMAKADIWLIRTYWDLEFPHPVLPNFDFIGGLHCRPAKPLPKEIEDFVQSSGEH 305

  Fly   303 GAIYFSLGSQVRSADLPPEKLKVFLEVFGSLKQRVLWKFEDESLPNLPANVKVQSWLPQGDILAH 367
            |.:.|||||.|.|  :..|:..|.......:.|:|||:||.:....|.:|.::..|:||.|:|.|
Mouse   306 GVVVFSLGSMVGS--ITEERANVIAAGLAQIPQKVLWRFEGKKPETLGSNTRLYKWIPQNDLLGH 368

  Fly   368 PNVKVFIAHGGLFGTQEAVYNGVPILGMPVYCDQHQNINQGKSAEYALGLDYRKVTVEELRGLLM 432
            ...:.||.|||..|..||:|:|:|::|:|::.||:.||...|:...|:.||:..::..:|...|.
Mouse   369 SKTRAFITHGGTNGIYEAIYHGIPVVGIPLFGDQYDNIVHLKAKGAAVRLDFLTMSSTDLHTALK 433

  Fly   433 ELIENPKYRNNIKKASRIFRDRPLGAMDTAIYWINYVIEHRGAPHLVAAGVHLPWYQFYLLDIVG 497
            .:..:|.|:.|..:.|||..|:|:..:|.|::||.:|:.|:||.||..|...|.|.|::.||::|
Mouse   434 TVTNDPSYKENAMRLSRIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRVAAHDLSWVQYHSLDVLG 498

  Fly   498 LGLAVILLPIVVL----ILICRRSSKPKSTPTKKK 528
            ..||.:|..:.:|    :..|::.:|   ...|||
Mouse   499 FLLACVLTVMFILKKCCLFCCQKLTK---AGRKKK 530

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt49B1	NP_611563.1	Glycosyltransferase_GTB-type	38..515	CDD:471961	150/502 (30%)
Ugt2b34	NP_705826.1	UDPGT	27..529	CDD:278624	154/526 (29%)