Protein Alignment Ugt49B1 and ugt2b3

DIOPT Version :10

• Sequence 1: NP_611563.1
• Gene: Ugt49B1 / 37420
• FlyBaseID: FBgn0027073
• Length: 532
• Species: Drosophila melanogaster
• Sequence 2: NP_001170812.2
• Gene: ugt2b3 / 100384898
• ZFINID: ZDB-GENE-100402-2
• Length: 527
• Species: Danio rerio
• Alignment Length: 526
• Identity: 146/526 - (27%)
• Similarity: 252/526 - (47%)
• Gaps: 61/526 - (11%)

  Fly    38 SHFMMTNAIIRELVKQGHEVTFITP----FSLAKEKLGSNYKEIVI-----PQYDFWPEIKEMTN 93
            ||::....::..|:.:||.||.:.|    |..|||....:|:...:     ...||..|:...
Zfish    30 SHWINLKIVLDTLLDRGHNVTVLMPDGALFMKAKESDRFSYQNFSVSTSAQDMQDFLDELLHF-- 92

  Fly    94 KNTVLEMTDLPTFAF-LRMVNV------MGIHTTDFALEQPEIQAVINEKNKIGKYDLLLAEQFF 151
              :|.||..|..... ::..::      ||:...|..|:.||:.    :|.|.||:|:||::..:
Zfish    93 --SVFEMEQLNLLQIQMKFFDLGSRHQDMGLSYCDGILKSPELM----DKLKTGKFDVLLSDPMY 151

  Fly   152 NEGALILGHLYQIPTITISTFGNANHLSQLFG-VVSPWSYVPHAYMPYTDRMTLWERIGNVAMSA 215
             ..:.|:..:..:|.:....|..|:.:.::.| :.:|.||||.|....||:|:..|||.|.....
Zfish   152 -PCSDIVAEVLNVPLVFTLRFSIAHTMERICGQIPAPPSYVPGAMSKLTDKMSFTERIFNTLFYL 215

  Fly   216 AEDLV-----REFSYYPGQDAVLKKHFSKLLDRVPTIKELERNISAILLNSYMPLASSRPMAYNM 275
            :.|..     ::|..|          :::...|..:..|:.......|:.:|......||...|.
Zfish   216 SMDTFSIIAWKKFDNY----------YTEYFGRPTSYCEMMGRADIWLIRTYWDFEFPRPFVPNF 270

  Fly   276 IPVGGLHIQPPKALPEHLQKFLDGA-THGAIYFSLGSQVRSADLPPEKLKVFLEVFGSLKQRVLW 339
            ..:||||..|.|.||:.:::|:..: ..|.:.|:|||.:..  :|.|...........:.|:|||
Zfish   271 KYIGGLHCTPAKPLPKDMEEFVQSSGDDGIVVFTLGSMIDK--VPKEMSNRIASALAQIPQKVLW 333

  Fly   340 KFEDESLPNLPANVKVQSWLPQGDILAHPNVKVFIAHGGLFGTQEAVYNGVPILGMPVYCDQHQN 404
            ::..|....|..|.::..|:||.|:|.||..:.||.|||..|..||:|:|||::|:|::.||..|
Zfish   334 RYGGEKPDTLGENTRIYKWMPQNDLLGHPKTRAFITHGGTNGIYEAIYHGVPMVGIPLFGDQPDN 398

  Fly   405 INQGKSAEYALGLD-YRKVTVEELRGLLMELIENPKYRNNIKKASRIFRDRPLGAMDTAIYWINY 468
            :....:...|:.:| .:.:..:||...|..:|.:|.|:.|..:.|||..|||:..:|.:::||.:
Zfish   399 MVHMTTRGAAVVVDSIKSMQPQELVDKLNTVINDPSYKENAMRLSRIHHDRPMKPLDESVFWIEF 463

  Fly   469 VIEHRGAPHLVAAGVHLPWYQFYLLDIVGLGLAVILLPIVV--------LILICRRSSKPKSTPT 525
            |:.::||.||.....:|.|||::.||:......|:.|.:.:        ::..|.||
Zfish   464 VMRNKGAKHLRVEAHNLTWYQYHCLDVFAFLTTVLTLVLYICFKMAKFFIMRCCFRS-------- 520

  Fly   526 KKKTKK 531
            |:|:||
Zfish   521 KRKSKK 526

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt49B1	NP_611563.1	Glycosyltransferase_GTB-type	38..515	CDD:471961	139/508 (27%)
ugt2b3	NP_001170812.2	UDPGT	20..523	CDD:278624	143/521 (27%)