DRSC/TRiP Functional Genomics Resources

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Protein Alignment Lapsyn and Lrrc26

DIOPT Version :9

Sequence 1:NP_611561.1 Gene:Lapsyn / 37418 FlyBaseID:FBgn0034602 Length:343 Species:Drosophila melanogaster
Sequence 2:NP_666229.1 Gene:Lrrc26 / 227618 MGIID:2385129 Length:331 Species:Mus musculus


Alignment Length:303 Identity:76/303 - (25%)
Similarity:110/303 - (36%) Gaps:68/303 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly    27 EVRKCTYGHIDKLLRIRCYDLDLKEVPQNLKSSVEVLDLSHNRIRKLKTSSFQRYTDIKFLMLYD 91
            |...|:.|.     :..|..|.|..||.:|...|..|.|.|||:..|...:|.....:.:|.|.:
Mouse    45 EACSCSLGG-----KANCSALALPAVPADLSWQVRSLLLDHNRVSALPPGAFANAGALLYLDLRE 104

  Fly    92 NMILSVEVGTFEPLTSLQEIDLSNNGLTTIPLELFQLPRLRNLYIDSNELTSLNLQALEKPIRAP 156
            |.:.||....|..|..||.:|||:|.|.|:|...|                        .|:|| 
Mouse   105 NRLRSVHARAFWGLGVLQWLDLSSNQLETLPPGTF------------------------APLRA- 144

  Fly   157 LEYLNVAGCELQELPD--LGILPKLWQLNASMNPLQNFRIDSLANMCHLQVIDLTKSQLSQCGCQ 219
            |.:|::||..|..|..  ||.||.|..|:...|.|.......|.|:..|.|:.|..:..: |.| 
Mouse   145 LSFLSLAGNRLALLEPSILGPLPLLRVLSLQDNSLSAIEAGLLNNLPALDVLRLHGNPWT-CNC- 207

  Fly   220 QVTNHLMMLGASPKFVPVCLEALDIRECPLPYNRT----IHSP--------------TFASCQTT 266
                         ...|:|..   :|:.|.|.:.|    ..||              .|..|..:
Mouse   208 -------------ALRPLCTW---LRKHPRPASETETLLCVSPRLQTLSLLTAFPDAAFKQCTQS 256

  Fly   267 LQFAETRSFWLFGAGCFGGVCFVLLIVIFCVIHCRRKRAQRRK 309
            |...:....:..|...|.....:.|.:...:..|..:|.:||:
Mouse   257 LAARDLAVVYALGPVSFLASLAICLALGSVLTACGARRRRRRR 299

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
LapsynNP_611561.1 leucine-rich repeat 39..59 CDD:275380 6/19 (32%)
LRR_8 58..118 CDD:290566 21/59 (36%)
leucine-rich repeat 60..83 CDD:275380 8/22 (36%)
leucine-rich repeat 84..107 CDD:275380 7/22 (32%)
LRR_RI <94..>249 CDD:238064 41/156 (26%)
LRR_8 106..167 CDD:290566 17/60 (28%)
LRR_4 106..145 CDD:289563 10/38 (26%)
leucine-rich repeat 108..130 CDD:275380 10/21 (48%)
leucine-rich repeat 131..154 CDD:275380 1/22 (5%)
leucine-rich repeat 157..178 CDD:275380 9/22 (41%)
leucine-rich repeat 179..202 CDD:275380 6/22 (27%)
Lrrc26NP_666229.1 LRR_8 72..131 CDD:290566 21/58 (36%)
LRR 1 72..93 8/20 (40%)
leucine-rich repeat 73..96 CDD:275380 8/22 (36%)
LRR 2 96..117 6/20 (30%)
leucine-rich repeat 97..120 CDD:275380 7/22 (32%)
LRR 118..141 CDD:197688 11/46 (24%)
LRR 3 120..141 10/44 (23%)
LRR_8 121..179 CDD:290566 26/82 (32%)
leucine-rich repeat 121..144 CDD:275380 11/46 (24%)
LRR 4 144..165 8/21 (38%)
leucine-rich repeat 145..168 CDD:275380 9/22 (41%)
LRR 5 168..191 6/22 (27%)
LRR_4 169..204 CDD:289563 9/34 (26%)
leucine-rich repeat 169..192 CDD:275380 6/22 (27%)
TPKR_C2 201..244 CDD:301599 10/60 (17%)
leucine-rich repeat 236..255 CDD:275380 2/18 (11%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 310..331
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
00.000

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